5itw

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'''Unreleased structure'''
 
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The entry 5itw is ON HOLD until Paper Publication
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==Crystal structure of Bacillus subtilis BacC Dihydroanticapsin 7-dehydrogenase==
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<StructureSection load='5itw' size='340' side='right' caption='[[5itw]], [[Resolution|resolution]] 1.19&Aring;' scene=''>
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Authors: Perinbam, K., Balaram, H., Row, T.N.G., Gopal, B.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5itw]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ITW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ITW FirstGlance]. <br>
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Description: Crystal structure of Bacillus subtilis BacC Dihydroanticapsin 7-dehydrogenase
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5itv|5itv]]</td></tr>
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[[Category: Perinbam, K]]
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydroanticapsin_7-dehydrogenase Dihydroanticapsin 7-dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.385 1.1.1.385] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5itw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5itw OCA], [http://pdbe.org/5itw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5itw RCSB], [http://www.ebi.ac.uk/pdbsum/5itw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5itw ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/BACC_BACSU BACC_BACSU]] Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the dehydrogenation of the C7-hydroxyl group in the 4S-tetrahydrotyrosine (4S-H4Tyr) to yield anticapsin (epoxycyclohexanonyl-Ala). It is not able to oxidize the 4R-H4Tyr diastereomer and the dihydrobacilysin dipeptide (L-Ala-4S-H4Tyr dipeptide).<ref>PMID:15609023</ref> <ref>PMID:23317005</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Dihydroanticapsin 7-dehydrogenase]]
[[Category: Balaram, H]]
[[Category: Balaram, H]]
[[Category: Gopal, B]]
[[Category: Gopal, B]]
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[[Category: Row, T.N.G]]
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[[Category: Perinbam, K]]
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[[Category: Row, T N.G]]
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[[Category: Oxidoreductase]]
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[[Category: Rossmann fold]]
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[[Category: Short-chain dehydrogenases/reductase]]

Revision as of 01:36, 11 March 2017

Crystal structure of Bacillus subtilis BacC Dihydroanticapsin 7-dehydrogenase

5itw, resolution 1.19Å

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