This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4pko
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | + | ||
==Crystal structure of the Football-shaped GroEL-GroES2-(ADPBeFx)14 complex== | ==Crystal structure of the Football-shaped GroEL-GroES2-(ADPBeFx)14 complex== | ||
| - | <StructureSection load='4pko' size='340' side='right' caption='[[4pko]], [[Resolution|resolution]] 3.84Å' scene=''> | + | <StructureSection load='4pko' size='340' side='right'caption='[[4pko]], [[Resolution|resolution]] 3.84Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4pko]] is a 28 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PKO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PKO FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[4pko]] is a 28 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PKO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PKO FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=BEF:BERYLLIUM+TRIFLUORIDE+ION'>BEF</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=BEF:BERYLLIUM+TRIFLUORIDE+ION'>BEF</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4pkn|4pkn]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4pkn|4pkn]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">groEL, groL, mopA, BN17_41231, BU34_16740, ECs5124, LF82_0923 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895]), groS, groES, mopB, BN17_41221, BU34_16745, ECs5123, LF82_0924 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pko FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pko OCA], [http://pdbe.org/4pko PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4pko RCSB], [http://www.ebi.ac.uk/pdbsum/4pko PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4pko ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pko FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pko OCA], [http://pdbe.org/4pko PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4pko RCSB], [http://www.ebi.ac.uk/pdbsum/4pko PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4pko ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| - | {{Large structure}} | ||
== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/Q548M1_ECOLX Q548M1_ECOLX]] Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity).[RuleBase:RU000419][HAMAP-Rule:MF_00600] [[http://www.uniprot.org/uniprot/Q7BGE6_ECOLX Q7BGE6_ECOLX]] Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity).[SAAS:SAAS018369_004_006304][RuleBase:RU000535][HAMAP-Rule:MF_00580] | [[http://www.uniprot.org/uniprot/Q548M1_ECOLX Q548M1_ECOLX]] Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity).[RuleBase:RU000419][HAMAP-Rule:MF_00600] [[http://www.uniprot.org/uniprot/Q7BGE6_ECOLX Q7BGE6_ECOLX]] Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity).[SAAS:SAAS018369_004_006304][RuleBase:RU000535][HAMAP-Rule:MF_00580] | ||
| Line 27: | Line 27: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Bacillus coli migula 1895]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Fei, X]] | [[Category: Fei, X]] | ||
[[Category: Laronde-Leblanc, N]] | [[Category: Laronde-Leblanc, N]] | ||
Revision as of 08:13, 17 April 2019
Crystal structure of the Football-shaped GroEL-GroES2-(ADPBeFx)14 complex
| |||||||||||
