Acyl carrier protein synthase

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Line 29: Line 29:
**[[4hc6]] – MtACPS<br />
**[[4hc6]] – MtACPS<br />
**[[3gwm]] - ACPS – ''Mycobacterium smegmatis''<br />
**[[3gwm]] - ACPS – ''Mycobacterium smegmatis''<br />
-
**[[3qmn]] - VcACPS – ''Vibrio cholera''
+
**[[3qmn]] - VcACPS – ''Vibrio cholera''<br />
 +
**[[5cxd]] – ACPS – ''Staphylococcus aureus''<br />
*ACPS complex
*ACPS complex
Line 56: Line 57:
**[[2wgf]] - MtACPS I (mutant)<br />
**[[2wgf]] - MtACPS I (mutant)<br />
**[[2was]] - yACPS I PPT domain – yeast<br />
**[[2was]] - yACPS I PPT domain – yeast<br />
-
**[[3oyt]] - ACPS I – ''Yersinia psetis''<br />
+
**[[3oyt]] - YpACPS I – ''Yersinia psetis''<br />
 +
**[[4xox]] – VcACPS I<br />
*ACPS I complex
*ACPS I complex
Line 65: Line 67:
**[[2bui]] - EcACPS I + octanoic acid<br />
**[[2bui]] - EcACPS I + octanoic acid<br />
**[[1f91]], [[2byx]], [[2byz]], [[2bz3]] - EcACPS I (mutant) + fatty acid substrate<br />
**[[1f91]], [[2byx]], [[2byz]], [[2bz3]] - EcACPS I (mutant) + fatty acid substrate<br />
-
**[[2wge]] - MtACPS I + antibiotic<br />
+
**[[2wge]], [[5ld8]] - MtACPS I + antibiotic<br />
**[[2wgg]] - MtACPS I (mutant) + antibiotic<br />
**[[2wgg]] - MtACPS I (mutant) + antibiotic<br />
**[[4c6u]], [[4c6v]], [[4c6w]], [[4c6x]], [[4c6z]], [[4c70]], [[4c71]], [[4c72]], [[4c73]] - MtACPS I + inhibitor<br />
**[[4c6u]], [[4c6v]], [[4c6w]], [[4c6x]], [[4c6z]], [[4c70]], [[4c71]], [[4c72]], [[4c73]] - MtACPS I + inhibitor<br />
Line 80: Line 82:
**[[3e60]] – ACPS II – ''Bartonella henselae''<br />
**[[3e60]] – ACPS II – ''Bartonella henselae''<br />
**[[3kzu]] - ACPS II – ''Brucella melitensis''<br />
**[[3kzu]] - ACPS II – ''Brucella melitensis''<br />
-
**[[3o04]] - ACPS II – ''Listeria monocytogenes''<br />
+
**[[3o04]], [[5sxo]] - ACPS II – ''Listeria monocytogenes''<br />
**[[4ddo]] - BvACPS II – ''Burkholderia vietnamiensis''<br />
**[[4ddo]] - BvACPS II – ''Burkholderia vietnamiensis''<br />
**[[1kas]], [[2gfw]] – EcACPS II<br />
**[[1kas]], [[2gfw]] – EcACPS II<br />
Line 90: Line 92:
**[[4ls5]] - BsACPS II <br />
**[[4ls5]] - BsACPS II <br />
**[[4ls6]] - BsACPS II (mutant)<br />
**[[4ls6]] - BsACPS II (mutant)<br />
-
**[[4qav]] - NmACPS II – ''Nisseria meningitidis''<br />
+
**[[4qav]], [[5cmo]] - NmACPS II – ''Nisseria meningitidis''<br />
-
**[[4r8e]] - ACPS II – ''Yersinia pestis''<br />
+
**[[4r8e]] - YpACPS II <br />
*ACPS II complex
*ACPS II complex
Line 111: Line 113:
**[[3gwa]], [[3gwe]] - ACPS III – ''Burkholderia pseudomallei''<br />
**[[3gwa]], [[3gwe]] - ACPS III – ''Burkholderia pseudomallei''<br />
**[[4dfe]], [[4efi]] - ACPS III – ''Burkholderia xenovorans''<br />
**[[4dfe]], [[4efi]] - ACPS III – ''Burkholderia xenovorans''<br />
-
**[[3il3]] - ACPS III – ''Haemophilus influenza''<br />
+
**[[3il3]] - HiACPS III – ''Haemophilus influenza''<br />
**[[3fk5]] - ACPS III – ''Xanthomonas oryzae''<br />
**[[3fk5]] - ACPS III – ''Xanthomonas oryzae''<br />
**[[3led]] - ACPS III – ''Pseudonomas palustris''<br />
**[[3led]] - ACPS III – ''Pseudonomas palustris''<br />
-
**[[2x3e]] - ACPS III <br />
+
**[[2x3e]] - PaACPS III <br />
 +
**[[5dwz]] - PaACPS III (mutant)<br />
**[[1ebl]], [[1hn9]], [[1hnk]], [[3il9]] - EcACPS III<br />
**[[1ebl]], [[1hn9]], [[1hnk]], [[3il9]] - EcACPS III<br />
**[[4ewp]] – ACPS III – ''Micrococcus luteus''<br />
**[[4ewp]] – ACPS III – ''Micrococcus luteus''<br />
**[[4ryb]] - NmACPS III <br />
**[[4ryb]] - NmACPS III <br />
**[[4wzu]] - VcACPS III-2 <br />
**[[4wzu]] - VcACPS III-2 <br />
-
**[[4x9k]] - VcACPS III-2 (mutant)<br />
+
**[[4x9k]], [[4x9o]] - VcACPS III-2 (mutant)<br />
 +
**[[5by7]] - ACPS III – ''Verrucosispora maris''<br />
 +
**[[1ub7]] - TtACPS III (mutant)<br />
 +
**[[4z19]], [[4ylt]] - YpACPS III <br />
*ACPS III complex
*ACPS III complex
Line 126: Line 132:
**[[1hnj]] - EcACPS III + malonyl-CoA<br />
**[[1hnj]] - EcACPS III + malonyl-CoA<br />
**[[2qx1]] - EcACPS III + decyl-CoA<br />
**[[2qx1]] - EcACPS III + decyl-CoA<br />
-
**[[1mzs]] - EcACPS III + inhibitor<br />
+
**[[1mzs]], [[5bnm]], [[5bnr]], [[5bns]] - EcACPS III + inhibitor<br />
 +
**[[5bqs]] - SpACPS III + inhibitor<br />
 +
**[[4z8d]] - HiACPS III + inhibitor<br />
**[[1u6s]] - MtACPS III (mutant) + lauroyl-CoA<br />
**[[1u6s]] - MtACPS III (mutant) + lauroyl-CoA<br />
**[[2qnx]], [[2qo1]] - MtACPS III + undecanoic acid<br />
**[[2qnx]], [[2qo1]] - MtACPS III + undecanoic acid<br />
Line 138: Line 146:
**[[4nhd]] - VcACPS III + CoA<br />
**[[4nhd]] - VcACPS III + CoA<br />
**[[4x0o]] - VcACPS III-2 + acetyl-CoA<br />
**[[4x0o]] - VcACPS III-2 + acetyl-CoA<br />
-
 
+
**[[5kp2]] - VcACPS III-2 + octanoyl-CoA<br />
}}
}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 11:14, 20 February 2017

Acyl carrier protein synthase complex with CoA and Mg+2 ion (cyan) 3hqj

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3D structures of acyl carrier protein synthase

Updated on 20-February-2017









References

  • Parris KD, Lin L, Tam A, Mathew R, Hixon J, Stahl M, Fritz CC, Seehra J, Somers WS. Crystal structures of substrate binding to Bacillus subtilis holo-(acyl carrier protein) synthase reveal a novel trimeric arrangement of molecules resulting in three active sites. Structure. 2000 Aug 15;8(8):883-95. PMID:10997907
  • Dym O, Albeck S, Peleg Y, Schwarz A, Shakked Z, Burstein Y, Zimhony O. Structure-function analysis of the acyl carrier protein synthase (AcpS) from Mycobacterium tuberculosis. J Mol Biol. 2009 Nov 6;393(4):937-50. Epub 2009 Sep 3. PMID:19733180 doi:10.1016/j.jmb.2009.08.065

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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