Fatty acid synthase
From Proteopedia
(Difference between revisions)
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**[[4v8w]] – MtFAS I – Cryo-EM<br /> | **[[4v8w]] – MtFAS I – Cryo-EM<br /> | ||
**[[4v8l]] – FAS – ''Mycobacterium smegmatis'' – Cryo-EM<br /> | **[[4v8l]] – FAS – ''Mycobacterium smegmatis'' – Cryo-EM<br /> | ||
| - | **[[1xkt]] – hFAS thioesterase domain – human<br /> | + | **[[1xkt]], [[4z49]] – hFAS thioesterase domain – human<br /> |
**[[2jfd]] – hFAS MAT domain<br /> | **[[2jfd]] – hFAS MAT domain<br /> | ||
**[[3hhd]] - hFAS KS-MAT domain<br /> | **[[3hhd]] - hFAS KS-MAT domain<br /> | ||
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**[[2vkz]] - yFAS α+β subunits + cerulenin<br /> | **[[2vkz]] - yFAS α+β subunits + cerulenin<br /> | ||
**[[2px6]] – hFAS thioesterase domain + orlistat<br /> | **[[2px6]] – hFAS thioesterase domain + orlistat<br /> | ||
| - | **[[4piv]] – hFAS (mutant) + NADP + inhibitor<br /> | + | **[[4piv]], [[5c37]] – hFAS (mutant) + NADP + inhibitor<br /> |
}} | }} | ||
== References == | == References == | ||
Revision as of 09:16, 14 May 2017
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3D structures of fatty acid synthase
Updated on 14-May-2017
References
- ↑ Smith S, Witkowski A, Joshi AK. Structural and functional organization of the animal fatty acid synthase. Prog Lipid Res. 2003 Jul;42(4):289-317. PMID:12689621
- ↑ Zhang W, Chakravarty B, Zheng F, Gu Z, Wu H, Mao J, Wakil SJ, Quiocho FA. Crystal structure of FAS thioesterase domain with polyunsaturated fatty acyl adduct and inhibition by dihomo-{gamma}-linolenic acid. Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):15757-62. Epub 2011 Sep 9. PMID:21908709 doi:10.1073/pnas.1112334108
