We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.
OBrochtasSandbox
From Proteopedia
(Difference between revisions)
| Line 15: | Line 15: | ||
And as a <scene name='75/750300/Geneticmutationsspacefilled/1'>spacefilled model</scene> | And as a <scene name='75/750300/Geneticmutationsspacefilled/1'>spacefilled model</scene> | ||
| - | < | + | |
| + | This <scene name='75/750300/T1221_spacefilled/1'>threonine</scene> when mutated to isoleucine resulted in ts lethal mutations in the sevenless and EGFR-like genes in D. melanogster | ||
Revision as of 18:06, 16 January 2017
==O'Brochta's Sandbox == 0
|
The Anopheles arabiensis Insulin Receptor's kinase domain was modeled by Brian Pierce for the 'An arab ts lethal project'
This shows the basic structure of the kinase domain with an . The ATP will sit between them just below Beta 1
shows the ATP binding site (purple) and the catalytic loop (green). Here it is as a .
These are found in other RTKs.
G1000S (magenta), A1133G (orange), T1221I (teal)
And as a
This when mutated to isoleucine resulted in ts lethal mutations in the sevenless and EGFR-like genes in D. melanogster
