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Nucleoside diphosphate kinase

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<StructureSection load='1ucn' size='450' side='right' caption='Human nucleoside diphosphate kinase complex with ADP, phosphate, TRIS and Ca+2 ion (green) (PDB entry [[1ucn]])' scene='48/487511/Cv/1'>
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<StructureSection load='1ucn' size='350' side='right' caption='Human nucleoside diphosphate kinase complex with ADP, phosphate, TRIS and Ca+2 ion (green) (PDB entry [[1ucn]])' scene='48/487511/Cv/1'>
== Function ==
== Function ==
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**[[4f36]] – TbNDK – ''Trypanosoma brucei''<br />
**[[4f36]] – TbNDK – ''Trypanosoma brucei''<br />
**[[1vya]] – NDK – maize<br />
**[[1vya]] – NDK – maize<br />
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**[[4s0m]], [[4w98]], [[4wbf]] – NDK – ''Acinetobacter baumannii''<br />
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**[[4s0m]], [[4w98]], [[4wbf]], [[5yih]], [[5yol]] – NDK – ''Acinetobacter baumannii''<br />
**[[5iol]], [[5iom]] - SmNDK – ''Schisostoma mansoni''<br />
**[[5iol]], [[5iom]] - SmNDK – ''Schisostoma mansoni''<br />
**[[5u2i]] – NDK – ''Naegleria fowleri''<br />
**[[5u2i]] – NDK – ''Naegleria fowleri''<br />
**[[5v6d]] – NDK – ''Neisseria gonnorrhoeae''<br />
**[[5v6d]] – NDK – ''Neisseria gonnorrhoeae''<br />
 +
**[[5x00]] – NDK – ''Vibrio cholerae''<br />
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**[[6ay1]] – NDK – ''Helicobacter pylori''<br />
*NDK complex with adenine derivative
*NDK complex with adenine derivative
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**[[4f4a]] - TbNDK + UDP<br />
**[[4f4a]] - TbNDK + UDP<br />
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*NDK complex with antiviral drug
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*NDK other complexes
**[[1mn9]], [[3fkb]] - DdNDK (mutant) + antiviral drug<br />
**[[1mn9]], [[3fkb]] - DdNDK (mutant) + antiviral drug<br />
**[[4cp5]] - DdNDK (mutant) + PMPAPP<br />
**[[4cp5]] - DdNDK (mutant) + PMPAPP<br />
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**[[5ui4]] - hNDK + imidazole derivative<br />
}}
}}
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 09:28, 15 August 2018

Human nucleoside diphosphate kinase complex with ADP, phosphate, TRIS and Ca+2 ion (green) (PDB entry 1ucn)

Drag the structure with the mouse to rotate

3D structures of nucleoside diphosphate kinase

Updated on 15-August-2018

4fky - TbNDK + GTP

References

  1. ↑ Janin J, Dumas C, Morera S, Xu Y, Meyer P, Chiadmi M, Cherfils J. Three-dimensional structure of nucleoside diphosphate kinase. J Bioenerg Biomembr. 2000 Jun;32(3):215-25. PMID:11768305
  2. ↑ Qiu Y, Zhao D, Butenschon VM, Bauer AT, Schneider SW, Skolnik EY, Hammes HP, Wieland T, Feng Y. Nucleoside diphosphate kinase B deficiency causes a diabetes-like vascular pathology via up-regulation of endothelial angiopoietin-2 in the retina. Acta Diabetol. 2016 Feb;53(1):81-9. doi: 10.1007/s00592-015-0752-x. Epub 2015 Apr, 23. PMID:25900369 doi:http://dx.doi.org/10.1007/s00592-015-0752-x
  3. ↑ Chen Y, Gallois-Montbrun S, Schneider B, Veron M, Morera S, Deville-Bonne D, Janin J. Nucleotide binding to nucleoside diphosphate kinases: X-ray structure of human NDPK-A in complex with ADP and comparison to protein kinases. J Mol Biol. 2003 Sep 26;332(4):915-26. PMID:12972261

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