Sandbox k11v

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 2: Line 2:
<StructureSection load='2wj7' size='340' side='right' caption='Structure of alpha-beta crystallin.' scene=''>
<StructureSection load='2wj7' size='340' side='right' caption='Structure of alpha-beta crystallin.' scene=''>
-
Amyloid fibrils were suspected for long to be the agents of Amyloid diseases,including Alzheimer’s,Parkinson’s and the prion conditions.But evidence suggests that smaller, often transient and polymorphic oligomers are the toxic entities.Segment of amyloid forming protein alpha-beta crystallin makes oligomeric complex which exhibits properties of other amyloid oligomers.The structure of oligomer shows a cylindrical barrel,made up of <scene name='77/771966/Six_anti-parallel_protein_abc/1'>six anti-parallel protein strands</scene> known as cylindrin.This segment(coloured in black) termed as <scene name='77/771966/Cylindrin_of_one_subunit/1'>K11V</scene> forms the cylindrin structure.
+
The interactive Molecular Tour below assumes that you are familiar with the journal article
 +
 
PDB'S are
PDB'S are
K11V (<scene name='77/771966/3sgo/1'>3SGO</scene>), K11V-Br2 (<scene name='77/771966/3sgm/1'>3SGM</scene>), K11V-Br8 (<scene name='77/771966/3sgn/1'>3SGN</scene>), K11VV2L (<scene name='77/771966/3sgp/1'>3SGP</scene>), K11V-TR (<scene name='77/771966/3sgr/1'>3SGR</scene>), and GDVIEV (<scene name='77/771966/3sgs/1'>3SGS</scene>).
K11V (<scene name='77/771966/3sgo/1'>3SGO</scene>), K11V-Br2 (<scene name='77/771966/3sgm/1'>3SGM</scene>), K11V-Br8 (<scene name='77/771966/3sgn/1'>3SGN</scene>), K11VV2L (<scene name='77/771966/3sgp/1'>3SGP</scene>), K11V-TR (<scene name='77/771966/3sgr/1'>3SGR</scene>), and GDVIEV (<scene name='77/771966/3sgs/1'>3SGS</scene>).
-
== Function ==
+
== Introduction ==
 +
 
 +
Amyloid fibrils were suspected for long to be the agents of Amyloid diseases,including Alzheimer’s,Parkinson’s and the prion conditions.But evidence suggests that smaller, often transient and polymorphic oligomers are the toxic entities.Segment of amyloid forming protein <scene name='77/771966/2wj7_full_structure/1'>alpha-beta crystallin</scene> makes oligomeric complex which exhibits properties of other amyloid oligomers.The structure of oligomer shows a cylindrical barrel,made up of <scene name='77/771966/Six_anti-parallel_protein_abc/1'>six anti-parallel protein strands</scene> known as cylindrin.This segment(coloured in black) termed as <scene name='77/771966/Cylindrin_of_one_subunit/1'>K11V</scene> forms the cylindrin structure.
-
== Disease ==
+
== Molecular Tour ==
== Relevance ==
== Relevance ==
-
== Structural highlights ==
+
== Notes & Reference ==
-
[[hello]]
+
-
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
+
</StructureSection>
</StructureSection>
== References ==
== References ==
<references/>
<references/>

Revision as of 07:21, 4 November 2017

Toxic Amyloid Small Oligomer’s atomic view

Structure of alpha-beta crystallin.

Drag the structure with the mouse to rotate

References

Retrieved from "http://52.214.119.220/wiki/index.php/Sandbox_k11v"
Personal tools