Sandbox S1
From Proteopedia
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1ACJ shows the crystal structure of Torpedo californica acetylcholinesterase (TcAChE) complexed with tacrine. | 1ACJ shows the crystal structure of Torpedo californica acetylcholinesterase (TcAChE) complexed with tacrine. | ||
| - | Tacrine is a '''reversible inhibitor''' of cholinesterase. It was the first FDA approved drug for the treatment of Alzheimer's disease. | + | Tacrine is a '''reversible inhibitor''' of cholinesterase<ref>pmid 1122334</ref>. It was the first FDA approved drug for the treatment of Alzheimer's disease. |
Tacrine’s ring is stacked between the aromatic rings of tryptophan 84 and phenylalanine 330 (W84 and F330). | Tacrine’s ring is stacked between the aromatic rings of tryptophan 84 and phenylalanine 330 (W84 and F330). | ||
Revision as of 13:37, 31 January 2019
Your Heading Here (maybe something like 'Structure')
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