Rho GTPase activating protein

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</StructureSection>
</StructureSection>
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==3D structures of Rho GTPase activating protein==
 
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
 
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{{#tree:id=OrganizedByTopic|openlevels=0|
 
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*RhoGAP 1
 
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**[[1ow3]], [[5m6x]], [[5m70]] - hRhoGAP 1 residues 198-439 + RhoA + GDP - human<br />
 
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**[[6r3v]] - hRhoGAP 1 GTPase-activating domain residues 1-439 + RhoA + GDP + Pi<br />
 
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**[[4wpc]] - yRhoGAP 1 F-BARR domain + inositol phosphate<br />
 
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**[[5my3]] - yRhoGAP 1 RhoGAP domain - yeast<br />
 
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*RhoGAP 2
 
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**[[4rtt]], [[4rug]], [[2gnc]] - hRhoGAP 2 SLIT-ROBO SH3 domain <br />
 
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**[[2dl8]] - hRhoGAP 2 SLIT-ROBO SH3 domain - NMR<br />
 
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*RhoGAP 4
 
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**[[2epd]] - hRhoGAP 4 SH3 domain - NMR<br />
 
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*RhoGAP 5
 
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**[[2ee4]] , [[2ee5]] - hRhoGAP 5 (mutant) RhoGAP domain - NMR<br />
 
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**[[5u4v]] - hRhoGAP 5 pseudoGTPase domain<br />
 
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*RhoGAP 7
 
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**[[3kuq]] - hRhoGAP 7 RhoGAP domain<br />
 
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**[[2kap]], [[2dky]] - hRhoGAP 7 SAM domain - NMR<br />
 
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*RhoGAP 9
 
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**[[2p0d]], [[2p0f]], [[2p0h]] - hRhoGAP 9 pleckstrin homology domain + phosphoinositide<br />
 
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*RhoGAP 10
 
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**[[2mio]] - hRhoGAP 10 SH3 domain - NMR<br />
 
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**[[2j59]] - hRhoGAP 10 ARF-binding domain + ADP-ribosylation factor<br />
 
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* RhoGAP 11
 
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**[[3eap]] - hRhoGAP 11A RhoGAP domain<br />
 
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* RhoGAP 12
 
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**[[6gvc]] - hRhoGAP 12 residues 683-837 + actin + ATP<br />
 
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*RhoGAP 15
 
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**[[3byi]] - RhoGAP 15 residues 262-473<br />
 
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*RhoGAP 20
 
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**[[3msx]] - hRhoGAP 20 RhoGAP domain + RhoA<br />
 
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*RhoGAP 21
 
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**[[2yuy]] - hRhoGAP 21 PDZ domain - NMR<br />
 
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**[[2dhj]] - hRhoGAP 21 pleckstrin homology domain - NMR<br />
 
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*RhoGAP 27
 
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**[[3pp2]] - hRhoGAP 27 pleckstrin homology domain<br />
 
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*RhoGAP 34 or slit-robo RhoGAP 2
 
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**[[5i6j]], [[5i7d]] - hRhoGAP 34<br />
 
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**[[5i6r]] - hRhoGAP 34 (mutant)<br />
 
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*RhoGAP 35
 
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**[[5irc]] - RhoGAP 35 + RhoA - rat<br />
 
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**[[6d4g]] - rRhoGAP 35 + GTP<br />
 
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*RhoGAP
 
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**[[1grn]] - hRhoGAP C-terminal + GTP-binding protein<br />
 
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}}
 
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 07:24, 16 December 2019

Human RhoGAP 1 (magenta) complex with RhoA (blue), GDP, MgF3 and Mg+2 ions (PDB code 1ow3)

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References

  1. Moon SY, Zheng Y. Rho GTPase-activating proteins in cell regulation. Trends Cell Biol. 2003 Jan;13(1):13-22. PMID:12480336
  2. Kandpal RP. Rho GTPase activating proteins in cancer phenotypes. Curr Protein Pept Sci. 2006 Aug;7(4):355-65. PMID:16918449
  3. Graham DL, Lowe PN, Grime GW, Marsh M, Rittinger K, Smerdon SJ, Gamblin SJ, Eccleston JF. MgF(3)(-) as a transition state analog of phosphoryl transfer. Chem Biol. 2002 Mar;9(3):375-81. PMID:11927263

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