Johnson's Monday Lab Sandbox for Insulin Receptor
From Proteopedia
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| - | == | + | ==Insulin Receptor== |
<StructureSection load='6sof' size='350' side='right' caption='Insulin Receptor with Four Insulin Bound - 6sof' scene=''> | <StructureSection load='6sof' size='350' side='right' caption='Insulin Receptor with Four Insulin Bound - 6sof' scene=''> | ||
This is a default text for your page '''Johnson's Monday Lab Sandbox for Insulin Receptor'''. Click above on '''edit this page''' to modify. Be careful with the < and > signs. | This is a default text for your page '''Johnson's Monday Lab Sandbox for Insulin Receptor'''. Click above on '''edit this page''' to modify. Be careful with the < and > signs. | ||
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==Structure== | ==Structure== | ||
| - | + | The insulin receptor is a [https://en.wikipedia.org/wiki/Transmembrane_protein] | |
===Conformational Changes=== | ===Conformational Changes=== | ||
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It was found that at least three insulin molecules would have to bound to the receptor for the receptor to take on its active “T-state” conformation <ref name="Uchikawa" />. The difference between have the fully bound state with four insulins and the three insulin bound state is minimal compared to the difference between two and three insulins bound <ref name="Uchikawa" />. | It was found that at least three insulin molecules would have to bound to the receptor for the receptor to take on its active “T-state” conformation <ref name="Uchikawa" />. The difference between have the fully bound state with four insulins and the three insulin bound state is minimal compared to the difference between two and three insulins bound <ref name="Uchikawa" />. | ||
| + | ==Type II Diabetes== | ||
== References == | == References == | ||
Revision as of 02:41, 23 March 2020
Insulin Receptor
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