Sandbox Reserved 1658
From Proteopedia
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The Neuropilin is a transmembrane protein which has been highly conserved through evolution. Two different types of Neuropilin exist:Neuropilin1 (NRP1) and Neuropilin2 (NRP2). They have 44% of similarity by comparing their amino acid sequences. In the human genome, it is located on the chromosome 10 and their molar weights flucatuate between 120 and 130 kDa. | The Neuropilin is a transmembrane protein which has been highly conserved through evolution. Two different types of Neuropilin exist:Neuropilin1 (NRP1) and Neuropilin2 (NRP2). They have 44% of similarity by comparing their amino acid sequences. In the human genome, it is located on the chromosome 10 and their molar weights flucatuate between 120 and 130 kDa. | ||
- | These proteins are particularly found in the membrane of the endothelial cells. | + | These proteins are particularly found in the membrane of the endothelial cells but the Neuropilin 1 is involved in several process such as axon guidance during the embryonic development, recognition of the Vascular Endothelial cell Growth Factor([[VEGF]]) and recognition of covid-19. |
== Function == | == Function == | ||
Revision as of 22:05, 5 January 2021
This Sandbox is Reserved from 26/11/2020, through 26/11/2021 for use in the course "Structural Biology" taught by Bruno Kieffer at the University of Strasbourg, ESBS. This reservation includes Sandbox Reserved 1643 through Sandbox Reserved 1664. |
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The Neuropilin is a transmembrane protein which has been highly conserved through evolution. Two different types of Neuropilin exist:Neuropilin1 (NRP1) and Neuropilin2 (NRP2). They have 44% of similarity by comparing their amino acid sequences. In the human genome, it is located on the chromosome 10 and their molar weights flucatuate between 120 and 130 kDa.
These proteins are particularly found in the membrane of the endothelial cells but the Neuropilin 1 is involved in several process such as axon guidance during the embryonic development, recognition of the Vascular Endothelial cell Growth Factor(VEGF) and recognition of covid-19.
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Function
Disease
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Structural highlights
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