Sandbox Reserved 1667

From Proteopedia

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== Function of your protein ==
== Function of your protein ==
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<scene name='87/873229/Protein_view_1/1'>THFA is a protein that binds to PYCR1 and works as a weak inhibitor. PYCR1 inhibits proline synthesis to P5C.</scene>
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<scene name='87/873229/Protein_view_1/1'>PYCR1 is an enzyme found in humans. It is a potential cancer therapy target. In this variation of the protein, the analog THFA binds to the enzyme PYCR1 and works as a weak inhibitor. PYCR1 is the enzyme that reverses the intermediate Pyrroline 5-carboxylate (P5C) in Proline synthesis. </scene>
== Biological relevance and broader implications ==
== Biological relevance and broader implications ==
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== Important amino acids==
== Important amino acids==
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<scene name='87/873229/Ligand_view/1'>Important amino acids in the ligand THFA are Ser233, Val231, Thr238, Ala237.</scene>
== Structural highlights ==
== Structural highlights ==

Revision as of 15:19, 14 April 2021

This Sandbox is Reserved from 01/25/2021 through 04/30/2021 for use in Biochemistry taught by Bonnie Hall at Grand View University, Des Moines, USA. This reservation includes Sandbox Reserved 1665 through Sandbox Reserved 1682.
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References

  1. ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
  2. ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644

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