2mxz

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==Bacteriophage T5 l-alanoyl-d-glutamate peptidase comlpex with Zn2+ (Endo T5-ZN2+)==
==Bacteriophage T5 l-alanoyl-d-glutamate peptidase comlpex with Zn2+ (Endo T5-ZN2+)==
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<StructureSection load='2mxz' size='340' side='right'caption='[[2mxz]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2mxz' size='340' side='right'caption='[[2mxz]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2mxz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bpt5 Bpt5]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MXZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MXZ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2mxz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T5 Escherichia virus T5]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MXZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MXZ FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">lys, T5.040, T5p039 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10726 BPT5])</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mxz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mxz OCA], [https://pdbe.org/2mxz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mxz RCSB], [https://www.ebi.ac.uk/pdbsum/2mxz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mxz ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mxz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mxz OCA], [https://pdbe.org/2mxz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mxz RCSB], [https://www.ebi.ac.uk/pdbsum/2mxz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mxz ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/LYS_BPT5 LYS_BPT5]] Calcium-dependent l-alanyl-D-glutamate peptidase. May induce lysis of bacterial cell wall.
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[https://www.uniprot.org/uniprot/ENLYS_BPT5 ENLYS_BPT5] Endolysin with L-alanyl-D-glutamate peptidase activity that degrades host peptidoglycans and participates with the holin in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer by hydrolyzing the link between L-alanine and D-glutamate residues.<ref>PMID:19919545</ref>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bpt5]]
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[[Category: Escherichia virus T5]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Kutyshenko, V P]]
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[[Category: Kutyshenko VP]]
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[[Category: Mikoulinskaia, G V]]
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[[Category: Mikoulinskaia GV]]
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[[Category: Prokhorov, D A]]
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[[Category: Prokhorov DA]]
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[[Category: Bacteriophage t5]]
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[[Category: Endolysin]]
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[[Category: Hydrolase]]
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[[Category: L-alanoyl-d-glutamate peptidase]]
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[[Category: Zn-containing]]
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Revision as of 08:10, 8 March 2023

Bacteriophage T5 l-alanoyl-d-glutamate peptidase comlpex with Zn2+ (Endo T5-ZN2+)

PDB ID 2mxz

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