Erythrocyte binding antigen

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'''Erythrocyte binding antigen''' or '''Duffy receptor''' (EBA) is a ''Plasmodium falciparum'' ligand which binds to erythrocytes. Some strains are dependent on sialic acid for binding<ref>PMID:22989878</ref>. For more details see [[Malaria Parasite Plasmodium falciparum Erythrocyte Binding Antigen 140]].
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'''Erythrocyte binding antigen''' or '''Duffy receptor''' (EBA) is a ''Plasmodium'' ligand which binds to erythrocytes. Some strains are dependent on sialic acid for binding<ref>PMID:22989878</ref>. For more details see [[Malaria Parasite Plasmodium falciparum Erythrocyte Binding Antigen 140]].
</StructureSection>
</StructureSection>
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*EBA-175
*EBA-175
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**[[1zrl]], [[1zro]] – EBA region II (mutant) <br />
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**[[1zrl]], [[1zro]] – PfEBA region II (mutant) - ''Plasmodium falciparum''<br />
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**[[2rji]] – EBA region VI <br />
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**[[2rji]] – PfEBA region VI <br />
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**[[4k2u]] – EBA + antibody<br />
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**[[4k2u]] – PfEBA + antibody<br />
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**[[4qex]] – EBA (mutant) + antibody<br />
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**[[4qex]] – PfEBA (mutant) + antibody<br />
*EBA-140
*EBA-140
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**[[4gf2]], [[4jno]] – EBA (mutant) <br />
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**[[4gf2]], [[4jno]] – PfEBA (mutant) <br />
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*Duffy receptor region II 198-525
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**[[5x6n]] – EBA region II – ''Plasmodium knowlesi'' <br />
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**[[3rrc]], [[4yfs]] – PvEBA region II – ''Plasmodium vivax'' <br />
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**[[5f3j]], [[6oan]], [[6oao]], [[6r2s]] – PvEBA region II + antibody<br />
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**[[4nuu]], [[4nuv]] – PvEBA region II + Duffy antigen/chemokine receptor<br />
}}
}}
== References ==
== References ==

Revision as of 07:35, 19 July 2021

EBA region II (mutant) complex with sulfate and Cl- ion (PDB code 1zro)

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3D Structures of erythrocyte binding antigen

Updated on 19-July-2021

References

  1. Lin DH, Malpede BM, Batchelor JD, Tolia NH. Crystal and Solution Structures of Plasmodium falciparum Erythrocyte-binding Antigen 140 Reveal Determinants of Receptor Specificity during Erythrocyte Invasion. J Biol Chem. 2012 Oct 26;287(44):36830-6. doi: 10.1074/jbc.M112.409276. Epub 2012, Sep 18. PMID:22989878 doi:10.1074/jbc.M112.409276

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Michal Harel

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