Erythrocyte binding antigen
From Proteopedia
(Difference between revisions)
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- | '''Erythrocyte binding antigen''' or '''Duffy receptor''' (EBA) is a ''Plasmodium | + | '''Erythrocyte binding antigen''' or '''Duffy receptor''' (EBA) is a ''Plasmodium'' ligand which binds to erythrocytes. Some strains are dependent on sialic acid for binding<ref>PMID:22989878</ref>. For more details see [[Malaria Parasite Plasmodium falciparum Erythrocyte Binding Antigen 140]]. |
</StructureSection> | </StructureSection> | ||
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*EBA-175 | *EBA-175 | ||
- | **[[1zrl]], [[1zro]] – | + | **[[1zrl]], [[1zro]] – PfEBA region II (mutant) - ''Plasmodium falciparum''<br /> |
- | **[[2rji]] – | + | **[[2rji]] – PfEBA region VI <br /> |
- | **[[4k2u]] – | + | **[[4k2u]] – PfEBA + antibody<br /> |
- | **[[4qex]] – | + | **[[4qex]] – PfEBA (mutant) + antibody<br /> |
*EBA-140 | *EBA-140 | ||
- | **[[4gf2]], [[4jno]] – | + | **[[4gf2]], [[4jno]] – PfEBA (mutant) <br /> |
+ | |||
+ | *Duffy receptor region II 198-525 | ||
+ | |||
+ | **[[5x6n]] – EBA region II – ''Plasmodium knowlesi'' <br /> | ||
+ | **[[3rrc]], [[4yfs]] – PvEBA region II – ''Plasmodium vivax'' <br /> | ||
+ | **[[5f3j]], [[6oan]], [[6oao]], [[6r2s]] – PvEBA region II + antibody<br /> | ||
+ | **[[4nuu]], [[4nuv]] – PvEBA region II + Duffy antigen/chemokine receptor<br /> | ||
}} | }} | ||
== References == | == References == |
Revision as of 07:35, 19 July 2021
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3D Structures of erythrocyte binding antigen
Updated on 19-July-2021
References
- ↑ Lin DH, Malpede BM, Batchelor JD, Tolia NH. Crystal and Solution Structures of Plasmodium falciparum Erythrocyte-binding Antigen 140 Reveal Determinants of Receptor Specificity during Erythrocyte Invasion. J Biol Chem. 2012 Oct 26;287(44):36830-6. doi: 10.1074/jbc.M112.409276. Epub 2012, Sep 18. PMID:22989878 doi:10.1074/jbc.M112.409276