Monoclonal Antibodies 3D structures

From Proteopedia

Revision as of 07:34, 9 October 2022

3D structures of Monoclonal Antibody

Updated on 09-October-2022

Humanized mouse antibody (hmFab) is a modified mFab which resembles more hFab. {{#tree:id=OrganizedByTopic|openlevels=0|

• Human Fab

• • 3n9g, 3giz, 3eo9, 1ad9, 2fb4, 2ig2, 1qlr, 2zkh, 1qbl, 1igi, 3kyk, 3kym, 3nfs, 3w9d, 5i76, 5nst, 5od8, 5odb, 5xrq, 6amj, 6cr1, 6h9x, 6rco, 6rcq, 6rcs, 6tcm, 6tcn, 6umh, 6umi, 6umj, 7dun, 7km6, 7n6p, 7pkl, 7ven – hFab mAb - human
    
  • 6amm, 6anp, 6ao0, 6tcp, 6tcq – hFab (mutant)
    
  • 3qct – hFab anti-lysophosphatidic acid
    
  • 5jrp – hFab anti-Marburg virus
    
  • 3u6r, 1nlb, 6meg, 6med, 6mee, 6mef, 6wo5, 6x9x - hFab anti-hepatitis C virus
    
  • 1b4j - hFab anti-γ- interferon
    
  • 6w73 - hFab anti-CD4
    
  • 6al4 - hFab anti-CD19
    
  • 1bey, 1bfo - hFab anti-CD52
    
  • 1t3f - hFab anti-IFN-γ
    
  • 1x9q - hFab anti-fluorescin
    
  • 2d7t - hFab anti-hydroxybutyrate
    
  • 2fjf, 7lsb, 7lsi - hFab anti-VEGF
    
  • 2gjj - hFab anti-ERBB-2
    
  • 4g6k - hFab anti-interleukin-1
    
  • 4hie, 4hih – hFab anti-Streptococcus pneumonia
    
  • 4lkc – hFab anti-PCSK9
    
  • 5dk3 – hFab anti-cell death-1 receptor
    
  • 3ls5 – hFab anti-tetrahydrocannabinol
    
  • 4g5z – hFab canakinumab
    
  • 1fh5 – hFab Mak33
    
  • 3hmw - hFab ustekinumab
    
  • 4k7p – hFab rhumab6 + mFab 10C4
    
  • 6hud – hFab anti-amyloidosis – Cryo EM
    
  • 6srv, 6srx, 6ss0, 6tul - hFab anti-arginase
    
  • 6e65 – hFab anti-malaria
    
  • 7bm5 – hFab anti-BamA
    
  • 7km6 – hFab anti-APOBEC3B
    
  • 6u1t - mFab anti-Nipa virus
    
  • 2yk1, 2ykl – hFab anti-nicotine
    

• Mouse Fab

• • 1i9i – mFab anti-testosterone
    
  • 1iqw - mFab anti-hFAS
    
  • 1dqm, 1dqq - mFab anti-lysozyme
    
  • 1g7h, 1g7i, 1g7j, 1g7l, 1g7m - mFab anti-lysozyme (mutant)
    
  • 1ck0 - mFab anti-angiotensin
    
  • 2fbj – mFab anti-galactan
    
  • 1mcp– mFab anti-phosphocholine
    
  • 1c12 – mFab anti-traseolide
    
  • 3d69 – mFab anti-factor IX
    
  • 3esu – mFab anthrax-neutralizing
    
  • 1emt – mFab anti-fulerene
    
  • 1i3g – mFab anti-ampicillin
    
  • 1j05, 1clo – mFab anti-carcinoembryonic antigen
    
  • 1jfq - mFab anti-phenylarsonate
    
  • 4a6y - mFab anti-hydroxy nitrophenyl acetyl
    
  • 1mqk - mFab anti-cytochrome C oxidase
    
  • 1p4i – mFab anti-GCN4 peptide
    
  • 1psk – mFab anti-GD2 ganglioside
    
  • 1rih – mFab anti-glycolyl GM3
    
  • 2aab – mFab anti-idiotypic
    
  • 2gsg – mFab anti-poly glutamine
    
  • 2uyl – mFab anti-Vibrio cholera protein
    
  • 1bln – mFab anti-glycoprotein
    
  • 5cp7 – mFab anti-sulfonamide 4C7
    
  • 4tuo, 4trp – mFab anti-neuroblastoma
    
  • 4qt5 – mFab anti-TSH receptor
    
  • 4oz4 – mFab anti-tau protein
    
  • 2v7h – mFab anti-mannopyranoside
    
  • 2xkn - mFab anti-EGFR
    
  • 2ymx - mFab anti-AChE
    
  • 32c2 - mFab anti-cytochrome P450 aromatase
    
  • 4aeh - mFab anti-AAHI
    
  • 4amk, 4at6 - mFab anti-porphrin
    
  • 4dvb – mFab Pro-Upa
    
  • 1fai, 2f19 – mFab anti-arsonate
    
  • 1a5f - mFab anti-E-selectin
    
  • 4ebq – mFab anti-vaccinia
    
  • 4h20 – mFab anti-ricin
    
  • 2orb - mFab anti-C-myc
    
  • 1sbs - mFab anti-HCG
    
  • 1seq - mFab anti-TRKA
    
  • 3ojd – mFab anti-indolicidin
    
  • 6bpb, 6bpd – mFab anti-Vivax invasion
    
  • 3gk8, 1m71, 12e8, 1yuh, 1fgn, 1a6t, 4isv, 4jj5, 3gnm, 1ae6, 3c5s, 1mam, 3vg0, 4kph, 1mlb, 2vl5, 1rmf, 2adg, 1s5i, 1f8t, 3sgd, 4dvb, 4otx, 4poz, 4s1d, 5dq9, 5h2b, 6c5h, 6c5i, 6c5j, 6c5k, 6dc7, 6fab, 6kx0, 6p4y, 6wt3, 6y54, 7c95, 7jvd – mFab
    
  • 3c08, 1yy8 - mFab commercial
    
  • 6a76 - mFab anti-ROBO1
    
  • 6vrt - mFab anti-metal
    
  • 6fbj - mFab anti-matrix melalloproteinase
    
  • 6gxx, 6i1o, 6qu9 - mFab anti-antitrypsin
    
  • 6lkt, 6ltg – mFab anti-herpesvirus
    
  • 5i30 – mFab anti-astrovirus
    
  • 6d9g – mFab anti-serotonin transporter
    
  • 7bg1 – mFab anti-FLAG
    
  • 6wx1 – mFab anti-hemorrhagic fever virus
    
  • 3we6, 3wfh, 3whx, 3wif – mFab anti-prostaglandin
    

• Anti-HIV Fab

• • 2pr4, 1dfb, 3piq, 3q6f, 3q6g, 4d9l, 4xml, 5uby, 5ubz, 7mf7, 7mf8, 7mf9, 7mfa, 7mfb - hFab anti-HIV
    
  • 3p30, 2xra – hFab 1281 anti-HIV + gp41 ectodomain
    
  • 3ngb – hFab anti-HIV + glycoprotein gp120
    
  • 6nc3, 6nc2 – hFab anti-HIV + glycoprotein gp120 + glycoprotein gp41 – Cryo EM
    
  • 3w9e – hFab anti-HIV 2 + glycoprotein D
    
  • 7kde, 7l86, 7l87, 7l88, 7l89, 7l8a, 7l8b, 7l8c, 7l8d, 7l8s, 7l8t, 7l8w, 7l8x, 7l8y, 7l8z, 7l90 – hFab + HIV protein – Cryo EM
    
  • 3idg, 3idi, 3idj, 3idm, 3idn, 3d0v, 2pw1, 2pw2, 3lex, 3ley, 4ydv, 6x58 – hFab anti-HIV + gp41 peptide
    
  • 3mnz - hmFab anti-HIV + gp41 peptide
    
  • 2qsc - hFab anti-HIV + envelope glycoprotein peptide
    
  • 3uji - hFab anti-HIV + envelope glycoprotein gp160 peptide
    
  • 3mlr, 3mls, 3mlt, 3mlu, 3mlv, 3mlw, 3mlx, 3mly, 3mlz – hFab 2557 anti-HIV + V3 peptide
    
  • 1q1j, 3ujj, 4xmk, 6db5, 6db6, 6db7 - hFab anti-HIV + glycoprotein gp120 peptide
    
  • 2hrp - hFab anti-HIV + HIV-1 protease peptide
    
  • 4zto - rFab anti-HIV R53 + glycoprotein gp120 peptide
    
  • 7mep - mrFab anti-HIV + glycoprotein gp120 – macaque – Cryo EM
    
  • 7mdt, 7mdu - mrFab anti-HIV + glycoprotein gp120 + gp41 – Cryo EM
    
  • 3cle, 3clf, 3cmo, 1h3p, 3oz9, 1mf2, 1nld, 1bog, 3mnv, 1il1, 5tr8, 7kkz - mFab anti-HIV
    
  • 1rzk – mFab anti-HIV + glycoprotein gp120
    
  • 3mo1 - hmFab anti-gp41
    
  • 3qq9 - hmFab anti-RSV
    
  • 4ztp - rFab anti-HIV R53 - rabbit
    
  • 4jo1, 4jo2, 4jo3, 4jo4 - rFab anti-HIV R56 + gp120
    
  • 6did – rFab anti-HIV 10A + glycoprotein gp160
    
  • 6p62 – rFab anti-HIV E70 + env NFL – Cryo EM
    

• Anti-CSP (circumsporozoite from malaria parasite) Fab

• • 6b0w, 6azx, 5bk5, 5bk3, 7rqp - hFab anti-CSP
    
  • 5bk0, 6axk, 6axl, 6azm, 6b0s, 6b5l, 6b5m, 6b5n, 6b5o, 6b5p, 6b5r, 6b5s, 6b5t, 6d11, 6d0x, 6d01 6o23, 6o26, 6pbv, 6pbw, 6uc5, 6w05, 6wfx, 6wfy, 6wfz, 6wg0, 6wg1, 6wg2, 7k75, 7k76, 7lkb, 7lkg, 7raj, 7rcs, 7rd3, 7rd4, 7rd9, 7rda, 7rm0, 7rm1, 7rqq, 7rqr, 7sg5, 7sg6 – hFab + CSP peptide
    
  • 6uud, 6x87, 6x8p, 6x8q, 6x8s, 6x8u, 7rlw, 7rlx, 7rly, 7rlz, 7rm3 – mFab + CSP peptide
    
  • 6e63, 6rcu, 6rcv, 6wn1, 7rxi, 7rxj, 7rxl, 7rxp, 7s0x, 7unb – hFab + CSP protein
    
  • 6mb3, 6mhg – hFab + CSP protein – Cryo EM
    
  • 6ohg, 6ule, 6x87 – mFab + CSP – Cryo EM
    
  • 6w00, 6wfw – hFab + immunoglobulin G-binding protein + CSP peptide
    
  • 6o24, 6o25, 6o28, 6o29, 6o2a, 6o2b, 6o2c, 6ulf, 6vln – hFab + LgVHH + CSP
    
  • 7jum – hscFv + P230
    
  • 7kjh – viVHH + P12p
    

• Anti-influenza virus Fab

• • 3qhz, 4fql, 4gxv, 6btj - hFab anti-influenza
    
  • 3qhf – hFab anti-influenza (mutant)
    
  • 4n8c – mFab + influenza peptide
    
  • 4gxu, 4ubd, 5vag, 5w42, 5xrt, 6b3m, 6mlm, 6p3r, 6p3s, 6pdx, 6uig – hFab + influenza virus hemagglutinin
    
  • 7mem, 7t3d, 7tz5 – hFab + influenza virus hemagglutinin – Cryo EM
    
  • 6lxi, 6lxj, 6lxk – hFab + influenza virus neuraminidase
    
  • 4lvh, 1qfu – mFab anti-influenza haemagglutinin
    
  • 2aep, 2aeq, 1nma, 1nmb, 1nmc – mFab + influenza virus neuraminidase
    
  • 6j9o – hscFv anti-influenza
    

• Anti-Ebola virus Fab

• • 3inu, 6n7u – hFab anti-Ebola
    
  • 6dg2 – mFab anti-Ebola
    
  • 6n7j - hFab anti-ebola + ebola peptide
    
  • 2qhr – mFab + Ebola envelope glycoprotein peptide
    
  • 6pci, 6dzl, 6dzm, 6uye – hFab + ebola spike proteins – Cryo EM
    
  • 6ea5, 6ea7, 6oz9 – hFab + ebola glycoprotein
    

• Other Fab

• • 1it9 - hmFab anti-hFAS
    
  • 6l8t - hmFab anti-hepatitis B
    
  • 2hwz – hmFab MEDI-493
    
  • 6e64 – rFab anti-malaria
    
  • 4idl – LgFab anti-cholera toxin
    
  • 1c5d, 1fn4 – Fab anti-acetylcholine receptor - rat
    
  • 6e8v – bFab-1
    
  • 6e9g – bFab-2
    
  • 6e9h – bFab-3
    
  • 6e9i – bFab-4
    
  • 6e9k – bFab-5
    
  • 6e9q – bFab-6
    
  • 6e9u – bFab-7
    
  • 7tqa – syFab - synthetic
    
  • 7tqb – syFab + DNA + RNA
    

• Fab: small molecule complex

• • 3bpc, 2r1w, 2r1x, 2r1y, 2r23, 2r2b, 2r2e, 2r2h, 1m7d - mFab + liposaccharide
    
  • 3qcu, 3qcv - hFab LT3015 + phospholipid
    
  • 1baf - mFab + hapten
    
  • 3l1o – mFab MN423 + Zn
    
  • 3i9g - mFab LT1009 + phospholipids
    
  • 3bz4, 3c6s, 1m7i, 1uz8– mFab + polysaccharide
    
  • 1cly, 1clz, 1s3k – hFab/mFab + polysaccharide
    
  • 2z92, 2z93, 2e27 - mFab 10C9 + ciguatoxin
    
  • 5b6f - mFab + leukotriene C4
    
  • 1wc7 – mFab 15A9 + phosphopyridoxyl-alanine
    
  • 2adi, 2adj – mFab Q425 + ion
    
  • 1i9j – mFab + testosterone
    
  • 1jn6, 1jnh, 1jnl, 1jnn – mFab 10G6D6 + estradiol
    
  • 1kfa – mFab + gibberellin
    
  • 1nc2, 1nc4 – mFab + dota
    
  • 2cju, 2uud – mFab anti-Phox + Phox-GABA
    
  • 2ddq - mFab + NHE-histidine
    
  • 1keg - mFab anti-photoproduct + DNA
    
  • 5cp3 – mFab anti-sulfonamide 4C7 + sulfonamide
    
  • 6pyd - mFab anti-marinobufagenin + marinobufagenin
    
  • 6nfn - mFab anti-cocaine + benzoylecgonine
    

• Fab: peptide complex

• • 4hha – hFab anti-cytomegalovirus + glycoprotein B peptide
    
  • 6vn1 – hFab + glycoprotein B peptide – Cryo EM
    
  • 6vjt – hFab + hepatitis B peptide
    
  • 6wn4 – hFab + lipase peptide
    
  • 6lra – hFab + tau peptide
    
  • 7c94 – hFab + podoplanin peptide
    
  • 2osl – hmFab + CD20 peptide
    
  • 3o41, 3o45 – mFab + fusion protein F1 peptide
    
  • 2w65 - mFab + collagen peptide
    
  • 3ixt - mFab commercial + peptide
    
  • 3c09, 1yy9 - mFab commercial + EGFR peptide
    
  • 2v17, 5mo3, 6bb4, 6dc8, 6dc9, 6dca, 6pxr, 6xli - mFab + tau peptide
    
  • 2hkf – mFab + carbonic anhydrase peptide
    
  • 2zpk – mFab + proteinase-activated receptor peptide
    
  • 3bae, 3bkj, 2r0w, 2r0z, 2ipu - mFab + amyloid peptide
    
  • 1ejo - mFab + foot-and-mouth virus peptide
    
  • 2a6d, 2a6i, 2a6j, 2a6k – mFab 36-65 + peptide
    
  • 3rkd - mFab + HEV-1 capsid peptide
    
  • 1n64, 4hzl, 7lki - mFab + hepatitis C capsid peptide
    
  • 1f90 – mFab + IL-2 peptide
    
  • 6p50, 6p67 – mFab + IL-7
    
  • 7q4q – mFab + LRG1 peptide
    
  • 2y06, 2y07, 2xzq – mFab + anti-Np murine germline peptide
    
  • 2y36, 3eyu, 3uo1, 3uyr, 3v52, 4qxt, 4qy8, 4qyo, 4r3s, 5mu2 – mFab + peptide
    
  • 3v4u - mFab + MHC-I antigen peptide
    
  • 1ktr – mFab + oligohistidine peptide
    
  • 1p4b – mFab + GCN4 peptide
    
  • 1zea – mFab anti-cholera toxin + peptide
    
  • 1sm3 – mFab anti-breast tumor + peptide
    
  • 2or9 - mFab anti-C-myc + peptide
    
  • 4tul, 4tuk, 4tuj – mFab anti-neuroblastoma + peptide
    
  • 4bh7, 4bh8 – mFab anti-ARS murine germline + peptide
    
  • 6sf6 – mFab + COMP peptide
    
  • 7doh – mFab + rhodopsin peptide
    
  • 6lz4 – rFab + MAP peptide
    

• Anti-SARS-CoV Fab

• • 4oaw, 7k3q - hFab anti-SARS
    
  • 7rnj - hFab anti-SARS + SARS spike peptide
    
  • 2ghw, 5y11, 6xe1, 6yla, 6ym0, 7d6i, 7bz5, 7dpm, 7e3o, 7eam, 7ean, 7jx3, 7k8v, 7k8w, 7l7d, 7l7e, 7m7w, 7n4i, 7n4j, 7n4l, 7n4m, 7nab, 7nx6, 7nx7, 7nx8, 7nx9, 7nxa, 7nxb, 7r6w, 7r6x, 7sbu, 7z0x, 7z0y - hFab anti-SARS + SARS spike protein
    
  • 6yor, 7akd, 7akj, 7cab, 7cac, 7cah, 7cai, 7cak, 7cwl, 7cwm, 7cwn, 7cwo, 7cyp, 7k8s, 7k8t, 7k8u, 7k8v, 7k8w, 7k8y, 7k8z, 7k90, 7ls9, 7lss, 7m42, 7n5h, 7p40, ]]7phg]], 7q6e, 7qti, 7qtj, [7qtk]], 7ra8, 7ral, 7s6k, 7s6l, 7u0p, 7upl, 7wcd - hFab anti-SARS + SARS spike protein – Cryo EM
    
  • 7l0n - hFab anti-SARS + SARS spike protein + ACE
    
  • 7cr5 - hFab anti-SARS + SARS nucleoprotein
    
  • 3bgf, 4f2m – mFab + SARS spike protein
    
  • 7dcc, 7dcx, 7dd2, 7dd8, 7dk4, 7dk5, 7dk6, 7dk7, 7w9e, 7w9f - mFab anti-SARS + SARS spike protein – Cryo EM
    
  • 7m53 – mFab + SARS spike peptide
    
  • 7deo, 7det, 7deu – mscFv + SARS spike protein
    

• Human Fab: protein complex

• • 3ux9, 4ypg, 4z5r– hFab anti-interferon + interferon
    
  • 2nyy, 2nz9 – hFab + botulinum neurotoxin
    
  • 3w2d – hFab + enterotoxin
    
  • 7ce2 – hFab + tetanus toxin
    
  • 7oh0, 7oh1 – hFab + tetanus toxin – Cryo EM
    
  • 4mxv – hFab anti-lymphotoxin-α + lymphotoxin-α
    
  • 2ybr, 2yc1 – hFab + scorpion toxin
    
  • 7so5, 7so7 - hFab + toxin B
    
  • 2r4r, 2r4s – hFab + adrenergic receptor
    
  • 4hj0 – hFab + GIP receptor
    
  • 6wmw – hFab + GFRAL receptor
    
  • 2vxq – hFab + pollen allergen
    
  • 3nfp, 3iu3 – hFab + interleukin-2 receptor
    
  • 2xqb, 4g6j, 4g6m - hFab + interleukin
    
  • 1s78 - hFab commercial + ERBB-2
    
  • 3hmx - hFab commercial + 12
    
  • 6wzm – hFab + IL-8
    
  • 6u6u - hFab + IL-36R
    
  • 3eoa, 3eob - hFab commercial + integrin
    
  • 6v4p - hFab + integrin – Cryo EM
    
  • 1h0d – hFab 26-2F + angiogenin
    
  • 1iqd – hFab BO2C11 + human factor VIII
    
  • 1nlo - hFab anti-factor IX + factor IX
    
  • 3skj – hFab + ephrin type-A receptor
    
  • 4dtg – hFab 2021 + tissue factor pathway inhibitor
    
  • 4k7p – hFab RHUMAB6 + mFab 10C4
    
  • 5xf1, 5xez – hFab + glucagon receptor
    
  • 4hj0, 6jbt, 6jjp, 6k0y, 7bxa, 7cgw, 7wvm – hFab + PD-1
    
  • 6wzj, 6wzk, 6wzl - hFab + chemokine
    
  • 6a3w - hFab + TNFR 9
    
  • 6rps - hFab + carbonic anhydrase
    
  • 6r2s – hFab + duffy receptor
    
  • 6al5 - hFab anti-CD19 + CD19
    
  • 7uic - hFab + CD19 + CD81
    
  • 6vja, 6y92, 6y97, 6y9a – hFab + CD20 – Cryo EM
    
  • 7o52 - hFab anti-CD22 + CD22
    
  • 7dha, 7duo - hFab anti-CD38 + CD38
    
  • 5tz2, 5tzt, 5tzu - hFab anti-CD47 + CD47
    
  • 6aod - hFab + coagulation factor XI
    
  • 6ss2, 6ss4, 6ss6 - hFab + arginase
    
  • 7lex, 7ley, 7lez, 7lf0, 7lf1, 7lf2 - hFab + arginase – Cryo EM
    
  • 7mpg - hFab + fusion glycoprotein – Cryo EM
    
  • 7nbx, 7ncs, 7nd0 - hFab + BAM complex – Cryo EM
    
  • 6s5a – hFab + LALA
    
  • 6w7s, 6wh9 – hFab + KR1
    
  • 6umx - hFab + growth factor 8
    
  • 6umg - hFab + CGRP receptor
    
  • 5ngv, 5nh3 - hFab + activin receptor
    
  • 6bfq, 6bfs – hFab + GM-CSF
    
  • 6bit – hFab + SIRP-alpha
    
  • 6t9e - hFab + platelet factor B
    
  • 6t9d - hFab + VEGF
    
  • 7o4y - hFab + anti-kappa VHH
    
  • 6fgb – hFab + FcRn
    
  • 7sht, 7shu, 7shy, 7shz – hFab + IgE-Fc
    
  • 7mn8 – hFab + HER2 + HER3 + NRG1b – Cryo EM
    
  • 7v5n – hFab + DNA
    
  • 7eow – hVHH + von Willenbrand factor
    
  • 5l0q – hFab + ADAM10
    
  • 7jwg – hFab + OspA
    
  • 4hjg, 4ioi – hFab + immunoglobulin G-binding protein + protein L peptide
    
  • 5i5k – hFab + complement C6
    
  • 5t6p, 5t78, 6kx1 – hFab + MUC1 peptide
    

• Human Fab: viral protein complex

• • 6nn3 – hFab + VP2 of parvovirus
    
  • 6iw0, 6iw2, 6ivz – hFab + yellow fever E protein
    
  • 3iyw – hFab mAb + West Nile virus surface protein
    
  • 7dwt, 7dwu – hFab + Dengue envelope glycoprotein – Cryo EM
    
  • 6weq, 6wer – hFab + dengue virus NS1c
    
  • 6cmg, 6cmi – hFab + Hendra virus glycoprotein
    
  • 6bp2 – hFab + Marburg virus glycoprotein
    
  • 7rfb, 7rfc – hFab + Hepatitis C virus glycoprotein
    
  • 5wna, 5wnb – hFab + Human respiratory syncytial virus glycoprotein
    
  • 5wn9 – hscFv + Human respiratory syncytial virus glycoprotein
    
  • 6txz – hFab + Hepatitis A virus protein
    
  • 6iea, 6ieb, 6iec, 6iek – hFab + Rift Valley fever virus protein
    
  • 6w09, 7cvz, 7cvy, 7cw0, 7cw2, 7cw3 – hFab + Chikungunya glycoproteins – Cryo EM
    
  • 6w1c – hFab + Mayaro virus glycoproteins – Cryo EM
    
  • 6vyv – hFab + Ross River virus glycoproteins – Cryo EM
    
  • 6dfi, 6dfj, 6jep, 6jfh, 6jfi, 7a3n, 7a3u, 7bpk, 7bq5 – hFab + zika protein
    
  • 6uoe – hFab + herpesvirus protein
    
  • 7cn2 – hFab + papilloma virus capsid – Cryo EM
    
  • 6wm9, 6wn1, 6wno, 6woz, 6wqo, 6wtu, 6wtv, 6wty - hFab + reticulocyte binding protein
    
  • 6ous, 7mmn – hFab + HRSV protein
    
  • 6wds, 6wdt – hFab + enterovirus glycoproteins – Cryo EM
    
  • 6h2y – hFab + Neisseria lipoprotein
    
  • 7ur4 – hFab + metapneumovirus glycoprotein F0 – Cryo EM
    
  • 3jcb, 3jcc - hFab + SIV gp120 + CD4 – CryoEM
    

• Mouse Fab: protein complex

• • 3kj4 – mFab 1D9 + reticulon-4 receptor
    
  • 3ncy – mFab + arginine agmatine antiporter
    
  • 2zch, 2zcl – mFab 8G8F5 + PSA
    
  • 2vc2, 2vdk, 2vdl, 2vdm, 2vdn, 5hdb - mFab + integrin
    
  • 7la4 - mFab + integrin – Cryo EM
    
  • 3kj6 – mFab + β-2 adrenoreceptor
    
  • 3d9a, 1bql, 1fbi, 2iff, 1fdl, 3hfm, 1c08, 1dqj, 1nby, 1nbz, 1ndg, 1ndm, 1p2c, 1ua6, 1uac, 1xgp, 1xgq, 1yqv, 1mlc, 1kip, 1kiq, 1kir – mFab HYHEL + lysozyme
    
  • 1ic4, 1ic5, 1ic7, 1j1p, 1j1o, 1j1x, 2dqc, 2dqd, 2dqe, 2dqf, 2dqg, 2dqh, 2dqi, 2dqj, 3a67, 3a6b, 3a6c - mFab HYHEL10 (mutant) + lysozyme
    
  • 4aei - mFab anti-AAHI + scorpion toxin
    
  • 4rgm, 4rgn, 4rgo – mFab + enterotoxin
    
  • 4ag4 - mFab + DDR1
    
  • 4f37 – mFab anti-amyloid-β + colicin E7
    
  • 3gi8, 3gi9 – mFab 7F11 + APCT transporter
    
  • 6cse, 6csf – mFab + AGCS symporter + Ala
    
  • 3ffd – mFab + parathyroid hormone-related protein
    
  • 2zuq – mFab + disulfide bond formation protein
    
  • 2zjs – mFab 56 + preprotein translocase SecYE
    
  • 2j88 – mFab + hyaluronidase
    
  • 4f9l, 4f9p – mFab anti-BTN3A1 + butyrophilin A1
    
  • 1wej – mFab E8 + cytochrome C
    
  • 2j4w, 2j5l – mFab + apical membrane antigen
    
  • 2nr6, 5vcn, 5vco, 5vyf – mFab + allergen
    
  • 2hlf, 2ht2, 2ht3, 2ht4, 2htk, 2htl, 2h2p, 2h2s, 2exw, 2exy, 2fee, 1ots – mFab + exchange transporter ClCA
    
  • 7kgv – mFab + neutral amino acid transporter
    
  • 2ez0, 2fec, 2fed, 1ott, 1otu - mFab + exchange transporter ClCA (mutant)
    
  • 1z3g – mFab 2A8 + ookinete surface protein
    
  • 1fj1, 1osp – mFab + outer surface protein
    
  • 1ymh – mFab + protein L (mutant)
    
  • 1v7m, 1v7n – mFab TN1 + thrombopoietin
    
  • 1fsk - mFab + pollen allergen
    
  • 1keg, 1ehl – mFab + DNA
    
  • 3liz – mFab 4C3 + aspartic protease
    
  • 3nid, 3nif, 3nig, 3t3m, 3t3p, 3v4p, 3v4v – mFab 10E5 + integrin
    
  • 7l8p – mFab 10E5 + integrin + drug
    
  • 3v6o – mFab + leptin receptor
    
  • 5tr1, 5tqq - mFab + Cl channel
    
  • 5t5f - mFab JAR5 + factor H binding protein
    
  • 5mi0, 4u1g, 4u0r, 6bpa, 6bpc, 6bpe - mFab + reticulocyte binding protein
    
  • 5dlm - mFab + matrix protein 2
    
  • 4zyp – mFab + fusion protein F0
    
  • 6a77, 6a78 - mFab anti-ROBO1 + roundabout homolog
    
  • 6a79 - mFab anti-ROBO1 (mutant) + roundabout homolog
    
  • 7jti – mFab + retinol-binding protein
    
  • 6mlk – mFab + DEBS
    
  • 6cxy, 6vel, 7stz – mFab + cadherin
    
  • 6i3z, 6hx4 – mFab + antitrypsin
    
  • 6nex – mFab anti-cocaine + ighg
    
  • 7a65, 7a69, 7a6c, 7a6e, 7a6f, 7neq, 7nez, 7nfd – mFab + ABCB + drug – Cryo EM
    
  • 6rnn, 6s3t – mFab + mycoplasma surface protein
    
  • 7jgj - mFab + immunoglobulin protease – Cryo EM
    
  • 6z2l – mFab + P113
    
  • 1sy6 – mFab + CD3
    
  • 3ubx – mFab + CD1d + beta-2-microglobulin
    
  • 6lyn – mFab + CD146
    
  • [[7zwi], 7zwm, 7zxf, 7zxg – mFab + P45/48
    
  • 4okv – mFab + anti-platelet aggregation protein
    
  • 3sge – mFab + R13 peptide
    
  • 3eys – mFab + peptide
    
  • 3opz – mFab + sialidase
    
  • 5hdq – mFab + MntC
    
  • 4kuc – mFab + ricin
    
  • 3u9u – mFab + Erbb4
    
  • 5c0n, 5d8j – mFab + fatty-acid binding protein
    
  • 3e8u – mFab + BNP peptide
    
  • 5vlp – mFab + convertase + LDLR peptide
    
  • 7q6c – mFab + lgVHH + complement C6
    
  • 6y90 – mFab + CD20 – Cryo EM
    
  • 5xbm – mFab + Scarb2
    
  • 4edx - mFab + nerve growth factor
    

• Mouse Fab: viral protein complex

• • 3i50, 1ztx – mFab E53 + West Nile virus envelope glycoprotein
    
  • 2r29, 3uyp, 3uze, 3uzq, 3uzv, 4l5f – mFab + Dengue envelope glycoprotein
    
  • 3fmg - mFab 4F8 + Simian rotavirus glycoprotein VP7
    
  • 3j1s, 6ewb – mFab + Vp1
    
  • 2xqy - mFab anti-pseudorabies virus + glycoprotein H
    
  • 3v7a, 7l5j - mFab + norovirus capsid protein
    
  • 6l62 - mFab + circovirus capsid protein – Cryo EM
    
  • 5mhr - mFab + reoovirus sigma 1
    
  • 4q0x, 5vxr - mFab + hepatitis C ivirus peptide
    
  • 6q0b - mFab + polioovirus capsid proteins – Cryo EM
    
  • 2i9l – mFab + vaccinia virus protein
    
  • 5eor, 5eoq – mFab + vaccinia virus protein A27 peptide
    
  • 4etq – mFab anti-vaccinia + IMV membrane protein
    
  • 6j5d - mFab + louping ILL virus protein – cryo EM
    
  • 6j5g, 6j5f - mFab + tick-borne encephalitis virus protein
    
  • 6uvo – mFab + HRSV protein
    
  • 6cxc – mFab + HRSV protein – Cryo EM
    
  • 6tys – mFab + Nipah virus glycoprotein – Cryo EM
    
  • 6vy5, 6vy6 – mFab + Nipah virus RBP
    
  • 7ebr, 7ebz, 7ec5, 7ecy – mFab + enterovirus glycoproteins – Cryo EM
    
  • 7syy, 7syz – mFab + Hendra virus glycoprotein
    
  • 7ki4, 7ki6 – mFab + Hendra virus glycoprotein – Cryo EM
    
  • 7m51, 7m52, 7m55 – mFab + MERS spike peptide
    

• Other Fab: protein complex

• • 2eks, 2yss - hmFab HYHEL10 + lysozyme
    
  • 2dqj - hmFab HYHEL10 (mutant) + lysozyme
    
  • 1l7i - hmFab + ERBB-2
    
  • 1bj1, 2vwe - hmFab + VEGF
    
  • 4gw1, 4gw5 - hmFab + CQFD meditop
    
  • 5jq6 - hmFab + ClfA
    
  • 4edw - hmFab + nerve growth factor
    
  • 3uaj, 3uc0 – Fab + envelope protein - chimpanzee
    
  • 3b9k – rFab + CD8
    
  • 6i9i – rFab + Rift Valley fever virus glycoprotein
    
  • 6t3f – rFab + Nipah virus glycoprotein
    
  • 6osh, 6osn, 6osv – rFab + ROR2
    
  • 6e62 – rFab + Pf48/45
    
  • 6h5n – raFab + malaria protein
    
  • 6zvf – raFab + galectin
    
  • 6icc, 6icf – raFab + S2P
    
  • 7o9s - raFab + hantavirus envelope polyprotein
    
  • 7nks, 7nrh - raFab + hantavirus envelope polyprotein
    
  • 6z06 - vFab + hantavirus envelope polyprotein – vole
    
  • 7b09 - vFab + hantavirus envelope polyprotein - Cryo EM
    
  • 6tyb - rmFab + SIV gp160 + CD4 – rhesus monkey
    
  • 7phv, 7pi2, 7pi3, 7pi7 - Fab + Cys-rich protective antigen – chicken
    

• Fab: protein ternary complex

• • 4cc8 – hFab + gp41 + gp120
    
  • 3j70 – hFab + gp41 + gp120 + CD4
    
  • 4mxw – hFab anti-lymphotoxin-α + lymphotoxin-α + lymphotoxin-β + TNFR 3
    
  • 6mid – hFab + zika E protein + zika M protein
    
  • 7cbp, 7kcr – hFab + zika E protein + zika M protein – Cryo EM
    
  • 6nha – hFab + beta microglobulin + IgG receptor
    
  • 7kpb – hFab + TNF + TNFR
    
  • 4hkz, 6b9z – hFab + protein L + immunoblobulin binding protein
    
  • 6b9y, 6bae, 6bah – hFab + protein L + meditope + immunoblobulin binding protein
    
  • 3bsz – mFab + transthyretin + retinol-binding protein
    
  • 2zck - mFab 8G8F5 + PSA + reaction intermediate
    
  • 3rhw, 3ri5, 3ria, 3rif – mFab + glutamate-gated Cl- channel + drug
    
  • 2jk5, 2w0f, 2dwd, 2dwe, 2hvj, 2hvk, 2hg5, 1ors, 1zwi, 7m2i, 7m2j - mFab + KcsA K+ channel + ion
    
  • 3hpl, 2ih1, 2ih3, 1orq - mFab + KcsA K+ channel (mutant) + ion
    
  • 1ynt – mFab 4F11E12 + protein L + major surface antigen p30
    
  • 2hmi, 1n5y, 1n6q, 1r0a, 1hys – mFab 28 + reverse transcriptase + DNA
    
  • 3klh – mFab + P66 RT + P51 RT + DNA
    
  • 3w11, 3w12 , 3w13 , 3w14, 4oga, 5kqv – mFab + insulin + insulin receptor
    
  • 5j3h – mFab + peptide + insulin receptor
    
  • 1t03 - mFab + Pol polyprotein + DNA
    
  • 1xcq, 1xct, 1xf5 - mFab + capsid C + protein L
    
  • 1yyl, 1yym - mFab + gp120 + CD4 mimic
    
  • 2vdo, 2vdp, 2vdq, 2vdr, 4z7q, 4z7o, 4z7n - mFab + integrin + peptide
    
  • 3ldb - CmFab + bifunctional arginine demethylase + α-ketogluterate
    

• Full Immunoglobulin

• • 1igy - hFab IgG1
    
  • 1igt, 6rnn, 6rux – mFab
    

• Fc Fragments

• • 1fcc - hFc IgG + streptococcal protein G C2 fragment
    

• Fv Fragments

• • 1ap2 – mFv C219
    
  • 1cfv – mFv FV4155
    

• Catalytic antibody

• • 1hkl, 3zl4, 2agj, 1rhh – hFab
    
  • 3o2v – hFab 1e9 (mutant)
    
  • 1axs - hFab Oxy-cope
    
  • 1d5i, 1d5b, 1d6v - hmFab Oxy-cope
    
  • 1uwe, 1uwg, 3cfj, 3cfk, 1c5b – hmFab
    
  • 1kn2, 1kn4, 1yei, 1yej, 1yek, 1ngw, 1ngx, 1ngy, 1ngz, 1ct8, 2gfb, 1lo0, 1lo2, 1lo3, 1lo4, 1um4, 1um5, 1um6, 2gjz, 2gk0, 1f3d, 1ru9, 1rua, 1ruk, 1rul, 1rum, 1rup, 1ruq, 1rur, 2aju, 15c8, 2rcs, 1hq4, 1cf8, 1kem, 1yeh, 1yec, 1yed, 1yee, 1eap, 3bd3, 3bd4, 3bd5, 1jgu, 1jgv, 3cle, 3clf, 5xqw, 5i0z – mFab
    
  • 1fl6, 1fl5 – mFab 28B4 (mutant)
    
  • 1mie, 1mj8, 1mju, 43c9 – mFab esterolytic
    
  • 1a4j - mFab Diels Alder
    

• Catalytic antibody complex

• • 1gaf, 3fo0, 3fct - hFab + hapten
    
  • 3o2w – hFab (mutant) + transition state analog
    
  • 2xtj – hFab 1D05 + proprotein convertase subtilisin/kexin
    
  • 3t2n – hFab + serine protease hepsin
    
  • 3r1g – hFab + beta-secretase 1
    
  • 2j6e – hFab IGM + igG1 Fc
    
  • 1e4k - hFc Igg1 + Fc-γ-Riii Complex
    
  • 1y0l, 3fo1, 3fo2, 1c5c - hmFab + hapten
    
  • 1n7m – mFab + methylmesoporphyrin
    
  • 1wc7 – mFab + phosphopyridoxyl alanine
    
  • 1y18, 3fct, 1a0q, 1kel, 1c1e, 1wcb, 2bmk, 1aj7, 25c8 – mFab + hapten
    
  • 1ncw – mFab 4C6 + benzoic acid
    
  • 43ca – mFab + nitrophenol
    
  • 35c8 – mFab 5C8 + inhibitor
    
  • 2dqt, 2dqu, 2dtm, 1kno, 1a4k, 1mh5, 1mj7, 1mjj, 1nd0 – mFab + transition state analog
    
  • 2ajs – mFab 7A1 + heptaethylene glycol
    
  • 1fig – mFab 1F7 + bicarboxylic acid
    
  • 2ajv, 2ajx, 2ajy, 2ajz, 2ak1 - mFab + cocaine derivative
    
  • 3ivk – mFab + RNA
    
  • 4dw2 – mFab + urokinase-type plasminogen activator
    
  • 1a3l – mFab 13G5 + inhibitor
    

• Single chain variable fragment (scFv)

• • 6ehy, 6ehx, 6ehw, 6ehv, 5j75, 5j74, 5c2b, 2a9n, 2a9m, 6tcs – hscFv
    
  • 6tco, 6tcr – hscFv (mutant)
    
  • 4kv5 – hscFv + peptide
    
  • 1n4x, 1moe, 5vf2, 5i4f, 5b3n, 4nko, 4nkm, 4nkd, 4h0i, 4h0g, 4gqp, 3umt, 3nn8 – mscFv
    
  • 4p49, 4p48, 4ouo – cscFv
    
  • 5yy4, 5yd5, 5yd4, 5yd3, 5fxc, 5a2l, 5a2j, 4h0h – mscFv + peptide
    
  • 6j11 – mscFv + MERS spike N-terminal
    

• scFv: protein complex

• • 6ck9 – hscFv + hFab + Gp41
    
  • 5uk2, 5uk1, 5uk0, 5ujz, 4yjz – hscFv + hemagglutinin
    
  • 5m2j – hscFv + TNF
    
  • 5jz7 – hscFv + NGF
    
  • 5jym, 5jyl – hscFv + cadherin
    
  • 6j71 - hscFv + ERBB-2
    
  • 7cu5 - hscFv + PD-1
    
  • 6pcu - hscFv + rotavirus VP4
    
  • 7a3o, 7a3p, 7a3q, 7a3t – hscFv + dengue protein
    
  • 6i07 - hscFv + EPCAM
    
  • 5f3j – mscFv + Duffy receptor
    
  • 6eqc, 5ogi – mscFv + hexon protein
    
  • 5lxa – mscFv + adiponectin receptor
    
  • 5kve – mscFv + Zika envelop protein
    
  • 5kov – mscFv + vp90
    
  • 3ab0 – mscFv + BCLA protein
    
  • 2znx, 1dzb – mscFv + lysozyme
    
  • 2kh2 – mscFv + interleukin
    
  • 7zwf – mscFv + P45/48
    
  • 5yy4, 5yd5, 5yd4, 5yd3, 5fxc, 5a2l, 5a2j, 4h0h – mscFv + peptide
    
  • 6j11 – mscFv + MERS spike N-terminal
    
  • 7k93 – mscFv + dengue protein
    

}}