DNA polymerase 3D structures

From Proteopedia

Revision as of 09:37, 6 February 2023

3D Structures of DNA polymerase

Updated on 06-February-2023 {{#tree:id=OrganizedByTopic|openlevels=0|

• DNA polymerase I

• • 1taq – TaDpo I - Thermus aquaticus
    
  • 1jxe – TaDpo I Stoffel fragment 290-832
    
  • 5ktq – TaDpo I Stoffel fragment + nucleotide
    
  • 5szt, 5e41, 6q4v, 6q4u, 6fbi, 6fbh, 6fbg, 6fbf, 6fbe, 6fbd, 6fbc, 5z3n, 5yth, 5ytg, 5ytf, 5yte, 5ytd, 5ytc, 5w6k, 5w6q – TaDpo I Stoffel fragment + DNA + nucleotide derivative
    
  • 5nkl – TaDpo I + DNA + pyridine derivative + pyrrol derivative
    
  • 5o7t – TaDpo I (mutant) + DNA + CTP derivative
    
  • 5oxj – TaDpo I + DNA + GMP derivative + imidazole derivative
    
  • 3ojs, 3oju, 1tau, 4dle, 4dlg, 4elt, 4elu, 4elv - TaDpo I + DNA
    
  • 4flt, 4flu, 4flv, 4flw, 4flx, 4fly, 4flz, 4fm0, 4fm1, 4fm2 – PaDpo I + DNA – Pyrococcus abyssi
    
  • 1s5j – SsDpo I - Sulfolobus solfataricus
    
  • 6dsy, 6dsx, 6dsw, 6dsv, 6dsu, 7k5o, 7k5p, 7k5r, 7k5q, 7k5s, 7k5t, 7k5u - GsDpo I + DNA - Geobacillus stearothermophilus
    
  • 3eyz, 6p5c - GsDpo I (mutant) + DNA
    
  • 6mu5, 6mu4, 6ur2, 6ur4 - GsDpo I + DNA + nucleotide derivative
    
  • 3ez5, 6ueu, 6ur9, 6us5 - GsDpo I (mutant) + DNA + nucleotide 
    
  • 3pv8, 3px0, 3px4, 3px6, 4dqi, 4dqp, 4dqq, 4dqr, 4dqs, 4ds4, 4ds5, 4dse, 4dsf, 4e0d, 4ez6, 4ez9, 4f2r, 4f2s, 4f3o, 4f4k, 4f8r - GkDpo I (mutant) + DNA – Geobacillus kaustophilus
    
  • 6vdc, 6vde – MsPol I – Mycobacterium smegmatis
    
  • 6vdd - MsDpo I + DNA + nucleotide derivative
    
  • 7pbk – Dpo I – Vibrio phage
    
  • 7r0k – Dpo I – Thermus phage
    

• DNA polymerase I klenow fragment or Taq polymerase

• • 2kzz, 1d8y, 2kzm – EcDpo I - Escherichia coli
    
  • 1qsl - EcDpo I + DNA
    
  • 1kfs, 1krp, 1ksp, 1kln - EcDpo I (mutant) + DNA
    
  • 1kfd, 1dpi - EcDpo I + nucleotide
    
  • 1d9d, 1d9f, 2kfn - EcDpo I + DNA + nucleotide
    
  • 2kfz - EcDpo I (mutant) + DNA + nucleotide
    
  • 1ktq - TaDpo I
    
  • 3po4, 3po5, 3rtv, 3sv3, 3sv4, 3syz, 3sz2, 4c8k, 4c8l, 4c8m, 4c8n, 4c8o, 4cch - TaDpo I + DNA
    
  • 4bwm, 4bwj - TaDpo I + DNA + RNA
    
  • 3py8 - TaDpo I (mutant) + DNA
    
  • 3m8r, 3m8s, 3lwl, 3lwm, 1qss, 1qsy, 1qtm, 2ktq, 3ktq, 4ktq, 3rr7, 3rr8, 3rrg, 3rrh, 3t3f, 4df4, 4df8, 4dfj, 4dfk, 4dfm, 4dfp, 7owf - TaDpo I + DNA + nucleotide
    
  • 3rrg, 4n56, 4n5s, 4xiu - TaDpo I (mutant) + DNA + nucleotide
    
  • 1xwl - GsDpo I
    
  • 2xo7, 3hp6, 3hpo, 2hhq, 2hhs, 2hht, 2hhu, 2hhv, 2hhw, 2hhx, 2hvh, 2hvi, 2hw3, 1xc9, 1ua0, 1ua1, 1njw, 1njx, 1njy, 1njz, 1nk0, 1nk4, 1nk5, 1nk6, 1nk7, 1nk8, 1nk9, 1nkb, 1nkc, 1nke, 1l3s, 2bdp, 4bdp, 2xy5, 2xy6, 2xy7, 2y1i, 2y1j, 3tan, 3tap, 3taq, 3tar, 3thv, 4b9l, 4b9m, 4b9n, 4b9s, 4b9t, 4b9u, 4b9v - GsDpo I + DNA
    
  • 4dsi, 4dsj, 4dsk, 4dsl, 4dwi - GsDpo I (mutant) + DNA
    
  • 3ht3, 1u45, 1u47, 1u48, 1u49, 1u4b, 1l3t, 1l3u, 1l3v, 1l5u, 1lv5, 3bdp, 3ti0, 4o0i, 4uqg - GsDpo I + DNA + nucleotide
    

• DNA polymerase II

• • 3maq, 3k57, 3k58, 3k59, 3k5l, 3k5m - EcDpo II (mutant) + DNA + nucleotide
    
  • 3k5n - EcDpo II (mutant) + DNA
    
  • 3k5o, 1q8i - EcDpo II (mutant)
    
  • 3o59, 5bkh - PhDpo II large subunit - Pyrococcus horikoshii
    
  • 2kxe - PhDpo II small subunit
    
  • 1qqc – DeDpo II – Desulfurococcus
    
  • 5ijl - PaDpo II large subunit
    
  • 5ihe - PaDpo II small subunit
    
  • 6hmf - PaDpo II small subunit (mutant)
    
  • 6hms - PaDpo II small+large subunits + DNA – Cryo EM
    
  • 6knb, 6knc - TkPol II small+large subunits + PCNA + DNA - Thermococcus kodakarensis – Cryo EM
    
  • 7rsr, 7rss, 7rsu, 7tqw - TkPol + purine derivative + DNA
    
  • 7om3, 7omb, 7omg - TkPol + DNA + nucleotide
    
  • 7e15 - TkPol II small subunit + GINS51 + ssDNA-specific exonuclease
    

• DNA polymerase III subunit alpha

• • 2hnh, 2hqa - EcDpo III subunit  catalytic fragment
    
  • 4jom - EcDpo III  subunit catalytic fragment (mutant)
    
  • 5m1s, 5fkw, 5fkv, 5fku - EcDpo III (mutant) subunits + DNA – Cryo EM
    
  • 1ok7 - EcDpo III residues 1-366 + EcDpo IV C-terminal
    
  • 2hpi, 2hpm - TaDpo III  subunit
    
  • 3e0d - TaDpo III  subunit + DNA
    
  • 3f2b, 3f2c, 3f2d, 4iqj – GkDpo III  subunit + DNA + nucleotide
    
  • 1zd7, 1zde, 3nzm, 5ol5, 5ol1 - SyDpo III  subunit – Synechocystis
    
  • 4gig - SyDpo III  subunit (mutant)
    
  • 2keq, 4kl5, 4kl6 - NpDpo III  subunit – Nostoc punctiforme
    
  • 4lx3, 4qfq - NpDpo III  subunit + nucleic acid binding tRNA/helicase
    
  • 5lew - MtPol III  subunit – Mycobacterrium tuberculosis
    
  • 7pu7 - MtDpo III  subunit + DNA
    

• DNA polymerase III subunit beta or sliding clamp

• • 1mmi, 2pol, 4k3s, 4pnv, 4pnw - EcDpo III subunit 
    
  • 2xur, 3f1v, 3pwe - EcDpo III subunit  (mutant)
    
  • 3d1e - EcDpo III subunit  + EcDpo II C-terminal
    
  • 1unn - EcDpo III subunit  + EcDpo IV little finger
    
  • 2avt - Dpo III  subunit – Streptococcus pyogenes
    
  • 2awa - Dpo III  subunit – Streptococcus pneumoniae
    
  • 4trt – DrDpo III  subunit – Deinococcus radiodurans
    
  • 2p1j – TmDpo III exonuclease domain – Thermotoga maritima
    
  • 1vpk - TmDpo III  subunit
    
  • 3t0p - Dpo III  subunit – Eubacterium rectale
    
  • 6ap4 - Dpo III  subunit – Acinetobacter baumannii
    
  • 6amq - Dpo III  subunit – Enterobacter cloacae
    
  • 5wyp, 5wce, 6izo, 6jir - Dpo III  subunit – Caulobacter crescentus
    
  • 5w7z - RcDpo III  subunit – Rickettsia conorii
    
  • 6man - Dpo III  subunit – Rickettsia bellii
    
  • 6d46 - RtDpo III  subunit – Rickettsia typhi
    
  • 6dlk - RrDpo III  subunit – Rickettsia rickettsii
    
  • 6d47 - MmDpo III  subunit – Mycobacterium marinum
    
  • 1jqj, 1jql - EcDpo III subunit (mutant)
    
  • 4tr6 - Pol III  subunit – Bacillus subtilis
    
  • 3p16, 3rb9, 4tr7 - MtPol III  subunit
    
  • 4tr8, 6ams - PsaPol III  subunit – Pseudomonas aeruginosa
    
  • 6pth - PsaPol III  subunit + griselimycin
    
  • 4s3i, 4rki - HpPol III  subunit – Helicobacter pylori
    
  • 6aig - Dpo III  subunit – Aeropyrum pernix
    
  • 6deg - BbDpo III  subunit – Bartonella birtlesii
    
  • 7rzm - Dpo III  subunit – Stenotrophomonas maltophilia
    
  • 8dt6 - Dpo III  subunit – Elizabethkingia anophelis
    

• DNA polymerase III subunit beta or sliding clamp complex

• • 3d1g, 3qsb, 4k3k, 4k3l, 4mjp, 4mjq, 4mjr, 4n94, 4n95, 4n96, 4n97, 4n98, 4n99, 4n9a, 4ovf, 4ovg, 4ovh, 4pnu - EcDpo III subunit  + inhibitor
    
  • 3bep - EcDpo III subunit  + DNA
    
  • 5x06 - EcDpo III subunit  + DnaA regulatory inactivator
    
  • 3d1f, 3q4j, 3q4k, 3q4l, 4k3l, 4k3m, 4k3o, 4k3p, 4k3q, 4k3r, 4k74, 6fvl, 7az5, 7az6, 7az7, 7az8, 7azc, 7azd, 7aze, 7azf, 7azg, 7azk, 7azl - EcDpo III  subunit + polypeptide
    
  • 6fvm - EcDpo III  subunit (mutant) + P7 peptide
    
  • 5g4q, 5g48, 5fxt, 5fve - HpPol III  subunit + NSAID drug
    
  • 5frq - HpPol III  subunit + DNA ligase peptide
    
  • 5dai - TkPol III  subunit + FEN-1 peptide
    
  • 5ah4, 5ah2, 5agv, 5agu – MsPol III  subunit + gricelimycin
    
  • 6drt – T4Dpo III  subunit + polypeptide - Enterobacteria phage T4
    
  • 6dj8 – Dpo III  subunit + polypeptide – Borrelia burgdorferi
    
  • 6fvo, 6fvn - MtPol III  subunit + P7 peptide
    
  • 6t7x - PaPol III  subunit
    
  • 4tsz, 6t7y - PaPol III  subunit + peptide
    
  • 6t8h - PaPol III  subunit + Dol II small subunit + DP2 – Cryo EM
    
  • 6djk - RtDpo III  subunit + polypeptide
    
  • 6dm6 - RcPol III  subunit + peptide
    
  • 6dly - MmPol III  subunit + peptide
    
  • 6ptv - RrPol III  subunit + griselimycin
    
  • 6ptr - BbPol III  subunit + griselimycin
    

• DNA polymerase III subunit gamma

• • 5c51, 5c52, 5c53 - hDpo III  subunit + DNA + nucleotide
    
  • 1njf, 1njg - EcDpo III subunit  N-terminal domains 1-2
    
  • 2gno - TmDpo III  subunit
    
  • 1xxh, 1jr3 - EcDpo III subunit ’
    
  • 1xxi - EcDpo III subunit ’ + nucleotide
    

• DNA polymerase III subunit delta

• • 1jqj, 1jql - EcDpo III subunit (mutant)
    
  • 1a5t - EcDpo III subunit ’
    
  • 1xxh, 1jr3 - EcDpo III subunit ’
    
  • 1xxi - EcDpo III subunit ’ + nucleotide
    
  • 3glh - EcDpo III subunit ’
    
  • 3glf - EcDpo III subunit ’ DNA
    
  • 3gli - EcDpo III subunit ’ DNA
    
  • 3glg - EcDpo III subunit ’mutant DNA
    

• DNA polymerase III subunit epsilon

• • 2gui – EcDpo III subunit  N-terminal
    
  • 1j53, 1j54 - EcDpo III subunit  N-terminal exonuclease domain
    
  • 2ido - EcDpo III subunit + HOT protein
    
  • 4gx8 - EcDpo III ε subunit/ EcDpo III α subunit
    
  • 4gx9 - EcDpo III ε subunit/ EcDpo III α subunit (mutant)
    
  • 2xy8 - EcDpo III subunit ,
    

• DNA polymerase III subunit tau

• • 2aya - EcDpo III subunit 
    
  • 3glh - EcDpo III subunit ’
    
  • 3glf - EcDpo III subunit ’ DNA
    
  • 3glg - EcDpo III subunit ’mutant DNA
    

• DNA polymerase III subunit xi

• • 3gli - EcDpo III subunit ’ DNA
    

• DNA polymerase III subunit theta

• • 2xy8 - EcDpo III subunit ,
    
  • 2axd, 2ae9, 1du2 - EcDpo III subunit - NMR
    

• DNA polymerase III subunit chi+phi

• • 1em8 - EcDpo III subunit ,
    
  • 3sxu - EcDpo III subunit , + peptide
    

• DNA polymerase IV

• • 4ir1, 4ir9, 4irc, 4ird, 4irk, 5zlv, 5yye, 5yyd, 5yv3, 5yv2, 5yv1, 5yv0, 5yuz, 5yuy, 5yux, 5yuw, 5yuv, 5yuu, 5yut, 5yus, 5yur - EcPol IV + DNA
    
  • 4r8u, 5c5j, 4q45, 4q44, 4q43, 6ig1 - EcPol IV + DNA + nucleotide
    
  • 6jup, 6juq - EcPol IV (mutant) + DNA + nucleotide
    
  • 2rdi - SsPol IV
    
  • 1s9f, 1s97, 1s0m, 1s0n, 1s0o, 1s10, 1n48, 1n56, 1jx4, 1jxl, 2xca, 2xcp, 2w8k, 2w8l, 2rdj, 2v9w, 2va2, 2va3, 2ia6, 2ibk, 2jef, 2jeg, 2jei, 2jej, 2imw, 2j6s, 2j6t, 2j6u, 2asd, 2asj, 2asl, 2atl, 2au0, 2c22, 2c28, 2c2d, 2c2e, 2c2r, 2agp, 2agq, 2bqr, 2bqu, 2br0, 2bq3, 3khg, 3khh, 3khl, 3khr, 3t5h, 3t5j, 3t5k, 3t5l, 3v6h, 3v6j, 3v6k, 4gc6, 4gc7, 4juz, 4jv0, 4jv1, 4jv2, 4qw8, 4qw9, 4qwa, 4qwb, 4qwc, 4qwd, 4qwe, 4ruc, 4rua, 4tqr, 4tqs, 5edw, 6vg6, 6vgm, [[[6vkp]], [6vnp]], 7kle, 7klf - SsPol IV + DNA + nucleotide
    
  • 3pr4, 3pr5, 2r8g, 2r8h, 2r8i, 2uvr, 2uvu, 2uvv, 2uvw - SsPol IV (mutant) + DNA + nucleotide
    
  • 2xc9, 3m9m, 3m9n, 3m9o, 2v4q, 2v4r, 2ago, 1ryr, 1rys, 2w9a, 2w9b, 2w9c, 3gii, 3gij, 3gik, 3gil, 3gim, 3qz7, 3qz8, 3pvx, 3pw0, 3pw2, 3pw4, 3pw5, 3pw7, 3raq, 3rax, 3rb0, 3rb3, 3rb4, 3rb6, 3rbd, 3rbe, 4hyk, 4fbt, 4fbu, 4g3i, 4rzr, 6l84, 6l97 - SsPol IV + DNA
    
  • 3fds – SsPol IV + PCNA B + PCNA C
    
  • 3bq2, 3bq0 – SaPol IV + DNA – Sulfolobus acidocaldarius
    
  • 3bq1, 4f4w, 4f4x, 4f4y, 4f4z, 4f50 - SaPol IV + DNA + nucleotide
    
  • 4nlg - SaPol IV (mutant) + DNA
    
  • 4dez – MsPol IV
    
  • 6jul – MsPol IV + DNA
    
  • 6jum, 6jun, 6juo – MsPol IV (mutant) + DNA
    
  • 6jus - MsPol IV + DNA + nucleotide
    
  • 6jur - MsPol IV (mutant) + DNA + nucleotide
    

• DNA polymerase V

• • 8gmt - EcPol V subumit umud + RecA + DNA + nucleotide – Cryo EM
    

• DNA polymerase from enterobacteria phage T7

• • 2ajq – T7Dpo (mutant) + thioredoxin (mutant) + DNA
    
  • 1zyq, 1x9m, 1x9s, 1x9w, 1tk0, 1skr, 1sks, 1skw, 1sl0, 1sl1, 1sl2, 1t7p, 6n7w - T7Dpo (mutant) + thioredoxin + DNA + nucleotide
    
  • 1t8e, 1tk5, 1tk8, 1tkd - T7Dpo + thioredoxin + DNA + nucleotide
    
  • 6p7e - T7Dpo + thioredoxin + DNA + nucleotide + peptide
    
  • 6n9x, 6n9w, 6n9v - T7Dpo + Gp4 + DNA + nucleotide derivative
    
  • 6n9u - T7Dpo + Gp4 + DNA + RNA + nucleotide derivative
    
  • 5ikn - T7Dpo + thioredoxin + DNA primase/helicase
    

• DNA polymerase

• • 2gv9 – HsvDpo – Herpes simplex virus
    
  • 7luf – HsvDpo + DNA
    
  • 5n2g, 5n2e – VvDpo – Vaccinia virus
    
  • 5n2h – VvDpo (mutant)
    
  • 5mdn – Dpo – Pyrobaculum calidifontis
    
  • 1bgx – TaDpo + TP7 antibody
    
  • 1ih7 – EpDpo - Enterobacteria phage RB69
    
  • 3cfo, 4i9l – EpDpo (mutant)
    
  • 1waf, 1waj - EpDpo + nucleotide
    
  • 3uiq, 4dtj, 4dtm, 4dtn, 4dto, 4dtp, 4dtr, 4dts, 4dtu, 4dtx, 4du1, 4du3, 4du4 - EpDpo + DNA
    
  • 3nci, 3lds, 3l8b, 3cq8, 3cfp, 3cfr, 3kd1, 3kd5, 4e3s - EpDpo (mutant) + DNA
    
  • 3ndk, 3ne6, 3ngi, 3nhg, 3nae, 3lzj, 3lzi, 2ozs, 2p5g, 2dy4, 1q9x, 1q9y, 1ig9, 3qep, 3rma, 3rmb, 3rmc, 3rmd, 3rwu, 3s9h, 3scx, 3si6, 3sjj, 3snn, 3spy, 3spz, 3sq0, 3sq1, 3sq2, 3sq4, 3sun, 3suo, 3sup, 3suq, 3tab, 3tae, 3taf, 3tag, 4i9q, 4j2a, 4j2b, 4j2d, 4j2e, 4khn, 4khq, 4khs, 4khu, 4khw, 4khy, 4ki4, 4ki6, 4m3r, 4m3t, 4m3u, 4m3w, 4m3x, 4m3y, 4m3z, 4m41, 4m42, 4m45, 5gnq - EpDpo (mutant) + DNA + nucleotide
    
  • 1clq, 3iuq, 7f4y - EpDpo + DNA + nucleotide
    
  • 2oyq, 2ozm, 2p5o, 2dtu, 3qei, 3qer, 3qes, 3qet, 3qev, 3qew, 3qex, 3qnn, 3qno, 4fj5, 4fj7, 4fj8, 4fj9, 4fjg, 4fjh, 4fji, 4fjj, 4fjk, 4fjl, 4fjm, 4fjn, 4fjx, 4fk0, 4fk2, 4fk4 - EpDpo (mutant) + DNA + nucleotide analog
    
  • 2atq – EpDpo + GP32
    
  • 1noy – T4Dpo + DNA
    
  • 1noz – T4Dpo residues 1-388
    
  • 2ex3 – BpDpo (mutant) + DNA terminal protein – Bacillus phage 29
    
  • 2py5, 2pzs, 1xhz, 1xi1 – BpDpo (mutant) + DNA
    
  • 2pyj, 2pyl - BpDpo (mutant) + DNA + nucleotide
    
  • 1xhx - BpDpo (mutant)
    
  • 3a2f - PfDpo + PCNA - Pyrococcus furiosus
    
  • 2jgu, 4ahc – PfDpo
    
  • 4ail – PfDpo + DNA
    
  • 1tgo, 7b06, 7b07, 7b08 - TgDpo – Thermococcus gorgonarius
    
  • 2vwk - TgDpo (mutant)
    
  • 7b0h – TgDpo + DNA
    
  • 2vwj, 2xhb – TgDpo (mutant) + DNA
    
  • 7b0f, 7b0g - TgDpo + DNA + nucleotide
    
  • 1wn7, 1wns, 5vu5 – TkDpo B
    
  • 5vu9, 5vu8, 5vu7, 5vu6, 5omf - TkDpo + DNA
    
  • 4k8z - TkDpo (mutant) + DNA
    
  • 6q4t - TkDpo (mutant) + DNA + nucleotide derivative
    
  • 1qht - ThDpo (mutant) – Thermococcus
    
  • 4k8x, 5omv, 5omq, 6is7, 6isf, 6isg, 6ish, 6isi - ThDpo (mutant) + DNA
    
  • 4yfu - Dpo (mutant) + DNA - Bacillus
    
  • 1d5a – DeDpo
    

• DNA polymerase alpha

• • 4e2i – hDpo α subunit β + large T antigen – human
    
  • 4y97 - hDpo α catalytic+B subunits
    
  • 5iud - hDpo α catalytic subunit + DNA
    
  • 6as7 - hDpo α catalytic subunit (mutant) + DNA
    
  • 4bpx - hDpo α catalytic subunit + DNA primase small subunit
    
  • 5exr - hDpo α catalytic+B subunits + DNA primase small+large subunits
    
  • 7opl - hDpo α catalytic+B subunits + DNA primase small+large subunits + Nsp1 – Cryo EM
    
  • 7u5c, 8d08 - hDpo α catalytic+B subunits + DNA primase small+large subunits + CST + DNA – Cryo EM
    
  • 4q5v - hDpo α catalytic subunit + DNA + RNA + aphidicolin
    
  • 4qcl, 7n2m - hDpo α catalytic subunit + DNA + RNA + nucleotide
    
  • 2keb - hDpo B - NMR
    
  • 1n5g, 1k0p, 1k18 - hDpo  zinc finger domain – NMR
    
  • 7uy7, 7uy8l - Dpo α B subunit + DNA primase small+large subunits – Tetrahymena thermophile - Cryo EM
    

• DNA polymerase beta

• • 4ppx - hDpo + spiroiminohydantoin + DNA
    
  • 1zjm, 1tv9, 1tva, 1bpx, 1bpz, 1zqa, 1zqb, 1zqc, 1zqd, 1zqf, 1zqg, 1zqh, 1zqi, 1zaj, 1zqk, 1zql, 1zqm, 1zqn, 1zqo, 1zqp, 1zqq, 1zqr, 1zqs, 1zqt, 1zqu, 1zqv, 1zqw, 1zqx, 1zqy, 1zqz, 1zqe, 3q8p, 3q8q, 3lk9, 3mby, 3isb, 3isc, 3gdx, 3rh4, 3rh5, 3rh6, 4gxi, 4gxj, 4gxk, 4kld, 4kle, 4klf, 4klg, 4klh, 4kli, 4klj, 4kll, 4klm, 4klo, 4klp, 4klq, 4kls, 4klt, 4klu, 1zqj, 4lvs, 4m2y, 4m47, 4nlk, 4nln, 4nlz, 4nm1, 4nm2, 4pgy, 4tup, 4tuq, 4tur, 4tus, 5wo0, 5wnz, 5wny, 5wnx, 5vs4, 5vs3, 5vs2, 5vs1, 5vs0, 5vrz, 5vry, 5vrx, 5vrw, 5vez, 5v1r, 5v1p, 5v1o, 5v1n, 5v1j, 5v1i, 5v1h, 5v1g, 5v1f, 5ugp, 5ugo, 5ugn, 5u9h, 5u8i, 5u8h, 5u8g, 5u2t, 5u2s, 5u2r, 5tzv, 5tbc, 5tbb, 5tba, 5tb9, 5tb8, 5j2k, 5j2j, 5j2i, 5j2h, 5j2g, 5j2f, 5j2e, 5j2d, 5j2c, 5j2b, 5j2a, 5j29, 5j0y, 5j0x, 5j0w, 5j0u, 5j0t, 5j0s, 5j0r, 5j0q, 5j0p, 5j0o, 5dbc, 5dbb, 5dba, 5db9, 5db8, 5db7, 5db6, 6g2q, 6ph5, 7ice, 7icf, 7ici, 7icj, 7icl, 7icm, 7icp, 7icr, 7ict, 7icg, 7ich, 7icj, 7ick, 7icm, 7icn, 7ico, 7icp, 7icq, 7icr, 7ics, 7ict, 7icu, 7icv, 7k97, 8icb, 8icc, 9icj, 9ick, 9icl, 9icm, 9icp, 9icw, 9icx, 9icy - hDpo  + DNA
    
  • 1bpy, 1mq2, 1mq3, 1zjn1, 2pxi, 2iso, 2isp, 2i9g, 2fmp, 2fmq, 2fms, 3jpn, 3jpo, 3jpp, 3jpq, 3jpr, 3jpt, 3jps, 3isd, 3c2k, 3c2l, 3c2m, 3rje, 3rjf, 3rjg, 3rjh, 3rji, 3rjj, 3rjk, 3tfr, 3tfs, 4do9, 4doa, 4dob, 4doc, 4mf2, 4mf8, 4mfa, 4mfc, 4mff, 4nxz, 4ny8, 4o5c, 4o5e, 4o5k, 4o9m, 4p2h, 4pgq, 4pgx, 4pha, 4phd, 4uaw, 4uay, 4uaz, 4ub1, 4ub2, 4ub3, 4ub4, 4ub5, 4ubb, 4ubc, 4z6f, 4z6e, 4z6d, 4z6c, 4yn4, 4ymo, 4ymn, 4ymm, 4rt3, 4rt2, 4rq8, 4rq7, 4rq6, 4rq5, 4rq4, 4rq3, 4rq2, 4rq1, 4rq0, 4rpz, 4rpy, 4rpx, 4php, 4phe, 4ph5, 5eoz, 5bpc, 5bom, 5bol, 7mz0, 7mz1, 7mz2, 7mz3, 7mz4, 7mzb, 7rbe, 7rbf, 7rbg, 7rbh, 7rbi, 7rbj, 7rbk, 7rbl, 7rbm, 7rbn, 7rbo, 7s9j, 7s9k, 7s9l, 7s9m, 7s9n, 7s9o, 7a9p, 7s9q, 8ica, 8ice, 8icf, 8icg, 8ich, 8ici, 8icj, 8ick, 8icl, 8icm, 8icn, 8ico, 8icp, 8icq, 8icr, 8ics, 8ict, 8icu, 8icv, 8icw, 8icx, 8icy, 8icz, 9ica, 9icb, 9icc, 9ice, 9icf, 9icg, 9ich, 9ici, 9icn, 9ico 9icq, 9icr, 9ics, 9ict, 9icu, 9icv - hDpo  + DNA + nucleotide
    
  • 2p66, 4f5n, 6n2t, 6n2s, 6n2r, 6mr8, 6mr7, 6e3x, 6e3w, 6e3v, 6e3r, 6dia, 6cub, 6cua, 6cu9, 6ctx, 6ctw, 6ctv, 6ctu, 6ctt, 6ctr,

6ctq, 6ctp, 6cto, 6ctn, 6ctm, 6ctl, 6ctk, 6ctj, 6cti, 6crh, 6crc, 6crb, 6cr9, 6cr8, 6cr7, 6cr6, 6cr5, 6cr4, 6cr3, 6cpq, 6cly, 6bem, 6bel, 6ph6, 6u2o, 6u6b, 6uok, 6uol, 6uom, 6w2m, 7k96 - hDpo  + DNA + nucleotide analog

• • 4f5o, 4f5p, 4f5q, 4f5r, 6dic, 6btf, 6bte, 6nkr, 6nks, 6nkt, 6nku, 6nkv, 6nkw, 6nkx, 6nky, 6nkz, 6nl0, 6pkz - hDpo  (mutant) + DNA + nucleotide analog
    
  • 3ogu, 4jwm, 4jwn, 4m9g, 4m9h, 4m9j, 4m9l, 4m9n, 4r63, 4r64, 4r65, 4r66 - hDpo  (mutant) + DNA
    
  • 5hhi, 5hhh - hDpo  + DNA + azanide derivative
    
  • 2v6z - hDpo  N-terminal (mutant)]] - NMR
    
  • 3k75, 3lqc - hDpo  + DNA repair protein XRCC1
    
  • 1rpl, 2bpc, 1bpe, 1bpb, 1bpd, 3uxn - rDpo  – rat
    
  • 2van, 1jn3, 3uxo, 3v7l- rDpo  (mutant)
    
  • 1dk2, 1dk3, 1bno, 1bnp - rDpo  N-terminal – NMR
    
  • 1nom - rDpo  C-terminal
    
  • 1huo, 1huz, 3v7j - rDpo  + DNA
    
  • 3uxp, 3v72, 3v7k - rDpo  (mutant) + DNA
    
  • 1bpe - rDpo  + nucleotide
    
  • 2bpf, 2bpg - rDpo  + DNA + nucleotide
    
  • 8e10 - mDpo 
    
  • 8e11 - mDpo  (mutant)
    
  • 3au2 – TtDpo β + GTP – Thermus thermophilus
    
  • 3b0x, 3b0y – TtDpo β (mutant) + GTP
    
  • 3au6, 3auo – TtDpo β + GTP + DNA
    
  • 4p4m, 4p4o, 4p4p - Dpo + DNA + nucleotide – Leishmania infantum
    

• DNA polymerase beta-like protein

• • 5hrb, 5hrd, 5hre, 7cpw - AsfvDpo + DNA – African swine fever virus
    
  • 5hr9, 5hrg - AsfvDpo (mutant) + DNA
    
  • 1jaj - AsfvDpo - NMR
    
  • 5hrf, 5hri, 5hrl - AsfvDpo + DNA + nucleotide
    
  • 5hrh, 5hrk - AsfvDpo (mutant) + DNA + nucleotide
    

• DNA polymerase gamma

• • 3ikm - hDpo 1+2
    
  • 3ikl, 2g4c - hDpo 2
    
  • 2jw5 - hDpo  BRCT domain
    
  • 1xsl - hDpo  catalytic domain
    
  • 1nzp - hDpo  lyase domain - NMR
    
  • 3pmn, 3pnc, 3mda, 2gws, 2bcq, 2bcr, 2bcs, 2bcu, 2bcv, 1xsp, 1rzt - hDpo  + DNA
    
  • 3mgh, 3c5f, 3c5g, 2pfn - hDpo  (mutant) + DNA
    
  • 3pml, 3mdc, 1xsn - hDpo  + DNA + nucleotide
    
  • 5c53, 5c52, 5c51 - hDpo  + DNA + nucleotide + pyrimidine derivative
    
  • 4ztz, 4ztu - hDpo  + DNA + nucleotide
    
  • 4k4g, 4k4h, 4k4i - hDpo  + DNA + nucleotide analog
    
  • 3mgi, 3hw8, 3hwt, 3hx0, 2pfo, 2pfp, 2pfq - hDpo  (mutant) + DNA + nucleotide
    

• DNA polymerase delta

• • 3e0j - hDpo 2+3
    
  • 3upq, 3uq0, 3uq2 - hDpo δ (mutant) + DNA
    
  • 4fo6 - hDpo δ (mutant) + DNA + nucleotide analog
    
  • 6s1m, 6s1n, 6s1o, 6tny - hDpo δ subunits catalytic+2+3+4 + PCNA + DNA + nucleotide analog – Cryo EM
    
  • 6tnz - hDpo δ subunits catalytic+2+3+4 + PCNA + FLAP endonuclease +DNA + nucleotide analog – Cryo EM
    
  • 7kc0 - hDpo δ + PCNA + POL31 + POL32 +DNA + nucleotide analog – Cryo EM
    

• DNA polymerase epsilon

• • 5vbn - hDpo subunits A+2
    

• DNA polymerase zeta

• • 3abd, 3abe - hDpo  catalytic subunit Rev3 + mitotic spindle assembly checkpoint protein Rev7
    
  • 6ekm, 6bi7, 6bcd, 6bc8 - hDpo  catalytic subunit + MAD2B
    
  • 3vu7, 4gk0, 6ws0 - hDpo  catalytic subunit + DNA repair protein Rev1 + MAD2B
    
  • 6ws5 - hDpo  catalytic subunit + DNA repair protein Rev1 + MAD2B + inhibitor
    
  • 4fjo, 4gk5 - hDpo  + hDpo  catalytic subunit + DNA repair protein Rev1 + MAD2B
    
  • 6v8p - hDpo  catalytic subunit + hDpo d subunits 3+small – Cryo EM
    
  • 6v93 - hDpo  catalytic+processivity subunits + hDpo d subunits 3+small + DNA + dCTP – Cryo EM
    

• DNA polymerase eta

• • 2i5o - hDpo  ubiquitin-binding zinc finger – NMR
    
  • 3wup - hDpo  ubiquitin-binding zinc finger
    
  • 3tq1, 4j9k, 4j9l, 4j9m, 4j9n, 4j9o, 4j9p, 4j9q, 4j9r, 4j9s, 6mp3 - hDpo  + DNA
    
  • 3jaa, 4dl2, 4dl3, 4dl4, 4dl5, 4dl6, 4dl7, 4eey, 4ecq, 4ecr, 4ecs, 4ect, 4ecu, 4ecv, 4ecw, 4ecx, 4ecy, 4ecz, 4ed0, 4ed1, 4ed2, 4ed3, 4ed6, 4ed7, 4ed8, 4o3n, 4o3o, 4o3p, 4o3q, 4o3r, 4o3s, 4q8e, 4q8f, 4rnm, 4rnn, 4rno, 3si8, 3mr2, 3mr3, 3mr5, 3mr6, 5l9x, 5l1l, 5l1k, 5l1j, 5l1i, 5kg7, 5kg6, 5kg5, 5kg4, 5kg3, 5kg2, 5kg1, 5kg0, 5kfz, 5kfy, 5kfx, 5kfw, 5kfv, 5kfu, 5kft, 5kfs, 5kfr, 5kfq, 5kfp, 5kfo, 5kfn, 5kfm, 5kfl, 5kfk, 5kfj, 5kfi, 5kfh, 5kfg, 5kff, 5kfe, 5kfd, 5kfc, 5kfb, 5kfa, 5jum, 5f9n, 5f9l, 5ewg, 5ewf, 5ewe, 5dqi, 5dqh, 5dqg, 5dlg, 5dlf, 5dgb, 5dga, 5dg9, 5dg8, 5dg7, 4yr3, 4yr2, 4yr0, 4yqw, 4yp3, 4ru9, 6mxo, 6m7v, 6m7u, 6m7t, 6m7p, 6m7o, 6d0z, 6d0m, 6mq8, 6pl7, 6pl8, 6plc, 6ui2, 6uqi, 6v5k, 6w5x, 6wk6, 7l69, 7lcd, 7m7l, 7m7m, 7m7n, 7m7o, 7m7p, 7m7q, 7m7r, 7m7s, 7m7t, 7m7u, 7m7y, 7m7z, 7m80, 7m81, 7m82, 7m83, 7m84, 7m85, 7m86, 7m87, 7m88, 7m89, 7m8a, 7m8b, 7m8c, 7m8d, 7u72, 7u73, 7u74, 7u75, 7u76, 7u77, 7u78, 7u79, 7u7a, 7u7b, 7u7c, 7u7d, 7u7e, 7u7g, 7u7f, 7u7i, 7u7j, 7u7k, 7u7l, 7u7r, 7u7s, 7u7t, 7u7u, 7u7v, 7u7w, 7u7x, 7u7y, 7u7z, 7u80, 7u81, 7u82, 7u83, 7u84, 8e85, 8e86, 8e87, [[8e88], 8e89, 8e8a, 8e8c, 8e8d, 8e8e, 8e8f, [[8e8g], 8e8h, 8e8j, 8e8k - hDpo  + DNA + nucleotide
    
  • 6pz3, 6q02 - hDpo  (mutant) + DNA + nucleotide
    
  • 5aga - hDpo  + nucleotide
    

• DNA polymerase iota

• • 3q8r, 3q8s, 3h4b, 3h4d, 3gv5, 3gv7, 3gv8, 3epg, 3epi, 2fll, 2fln, 2flp, 2dpi, 2dpj, 2alz, 1zet, 1t3n, 4ebc, 4ebd, 4ebe, 4fs1, 4fs2, 4eyh, 4eyi, 3g6v, 3g6x, 3g6y, 5ulx, 5ulw, 5kt7, 5kt6, 5kt5, 5kt4, 5kt3, 5kt2 - hDpo  + DNA + nucleotide
    
  • 3ngd, 3osn, 3h40 - hDpo  catalytic fragment + DNA 
    
  • 2ktf - hDpo  + ubiquitin
    
  • 2l0f, 2l0g - hDpo + ubiquitin – NMR
    
  • 2khu - hDpo ubiquitin binding motif – NMR
    
  • 2khw - hDpo ubiquitin binding motif + ubiquitin – NMR
    
  • 2kwu, 2kwv - mDpo  C-terminal + ubiquitin - NMR
    
  • 3ai4 - mDpo /yEGFP
    

• DNA polymerase kappa

• • 1t94 - hDpo 
    
  • 3in5, 5w2c, 5w2a, 5t14 - hDpo  + DNA
    
  • 2w7o, 2w7p, 2oh2, 3pzp, 4u6p, 6cst, 6bs1, 6brx, 5w2a, 5w2c - hDpo  + DNA + nucleotide
    
  • 7nv0, 7nv1 - hDpo  + PCNA + DNA + nucleotide
    
  • 4u7c, 4y6p - hDpo  + DNA + benzopyrene derivative
    
  • 2lsi - hDpo  peptide + hRev1
    
  • 2lsk - mDpo  + DNA repair protein Rev1
    

• DNA polymerase lambda

• • 5cb1 – hDpo
    
  • 5iio, 5iin, 5iim, 5iil, 5iik, 5iij, 5iii, 5ddm – hDpo + DNA
    
  • 5cp2 – hDpo (mutant) + DNA
    
  • 5dkw, 5ca7, 4xus, 4xrh, 4xq8, 4xa5, 4x5v, 7m07, 7m08, 7m09, 7m0a, 7m0b, 7m0c, 7m0d, 7m0e – hDpo + DNA + nucleotide
    
  • 5cwr, 5cr0, 5cj7, 5chg, 7m43, 7m44, 7m45, 7m46, 7m47, 7m48, 7m49, 7m4a, 7m4b, 7m4c, 7m4d, 7m4e, 7m4f, 7m4h, 7m4i, 7m4j, 7m4k, 7m4l – hDpo (mutant) + DNA + nucleotide
    
  • 5ddy – hDpo + nucleotide
    

• DNA polymerase mu or DNA-directed DNA/RNA polymerase

• • 2htf, 2dun - hDpo  BRCT domain residues 24-143 – NMR
    
  • 4lzd - hDpo  residues 132-494
    
  • 4lzg, 5tyz, 5tyy, 5tyx, 5tyw, 5tyv, 5tyu, 5tyg, 5tyf, 5tye, 5tyd, 5tyc, 5tyb, 5txz, 5txx, 5tws, 5twr, 5twq, 5twp, 5zlc - hDpo  residues 132-494 + DNA
    
  • 4yd2, 4ycx - hDpo  residues 132-494 (mutant) + DNA
    
  • 6ak5 - hDpo  residues 132-397+411-494 + nucleotide derivative
    
  • 6ipn, 6ipm, 6ipl, 6ipk, 6ipj, 6ipi, 6iph, 6aec, 6aeh, 6ak6 - hDpo  residues 132-397+411-494 (mutant) + nucleotide derivative
    
  • 6vez, 6vf0, 6vf1, 6vf2, 6vf3, 6vf4, 6vf5, 6vf6, 6vf7, 6vf8, 6vf9, 6vfa, 6vfb, 6vfc, 7co6, 7co8, 7co9, 7coa, 7cob, 7cod, 7kss, 7kst, 7ksu, 7ksv, 7ksw, 7ksx, 7ksy, 7ksz, 7kt0, 7kt1, 7kt2, 7kt3, 7kt4, 7kt5, 7kt6, 7kt7, 7kt9, 7kta, 7ktb, 7ktc, 7ktd, 7kte, 7ktf, 7ktg, 7kth, 7kti, 7ktj, 7ktk, 7ktl, 7ktm, 7ktn - hDpo  + DNA + nucleotide derivative
    
  • 4m04, 4m0a, 4yd1, 6ipg, 6ipf, 6ipe, 6ipd, 5vz7, 5vz8, 5vz9, 5vza, 5vzb, 5vzc, 5vzd, 5vze, 5vzf, 5vzg, 5vzh, 5vzi, 6ak8, 6ak9, 6akh, 6p1m, 6p1n, 6p1o, 6p1p, 6p1q, 6p1r, 6p1s, 6p1t, 6p1u, 6p1v, 6p1w, 7coc - hDpo  residues 132-494+411-494 (mutant) + DNA + nucleotide derivative
    
  • 2ihm - mDpo  catalytic domain + DNA – mouse
    

• DNA polymerase nu

• • 4xvi, 4xvk, 4xvl, 4xvm – hDpo nu catalytic domain + DNA
    

• DNA polymerase chi or repair DNA polymerase chi

• • 2m2t – AsfvDpo X – African swine fever virus – NMR
    
  • 2m2u, 2m2v – AsfvDpo X + nucleotide – NMR
    
  • 2m2w – AsfvDpo X + nucleotide + DNA – NMR
    
  • 5xma, 5xm9, 5xm8 – AsfvDpo X + DNA
    
  • 2w9m – DrDpo X

• DNA polymerase theta

• • 5a9j – hDpo helicase domain 1-894
    
  • 5a9f, 5aga – hDpo helicase domain + nucleotide
    
  • 4x0p, 4x0q – hDpo helicase domain + nucleotide + DNA
    
  • 6xbu, 7zus – hDpo polymerase domain 1819-2590 + nucleotide + DNA
    
  • 7zx0, 7zx1, 8e23, 8e24 – hDpo polymerase domain + inhibitor + DNA
    
  • 8ef9, 8efc, 8efk – Dpo polymerase domain + nucleotide + DNA – Lates calcarifer
    

• DNA polymerase from yeast

• • 3oiq - yDpo  + cell division control protein 13
    
  • 3flo, 3lgb - yDpo  subunits A,B
    
  • 4b08, 4fvm - yDpo  subunit A
    
  • 4fxd, 4fyd - yDpo  subunit A + RNA + DNA
    
  • 5oki - yDpo  subunit A + DCC1 + chromosome fidelity protein
    
  • 3iay - yDpo  catalytic subunit + DNA
    
  • 6p1h - yDpo  catalytic+small+3 subunits + DNA + nucleotide – Cryo EM
    
  • 6wjv - yDpo II  – Cryo EM
    
  • 6hv8 - yDpo II  subunit A+B – Cryo EM
    
  • 3oha, 3ohb, 3mfh - yDpo  (mutant) + DNA
    
  • 6i8a, 6qib, 7r3x, 7r3y - yDpo II  subunit A + DNA + nucleotide 
    
  • 6g0a, 6fwk, 3mfi, 4m8o - yDpo II  subunit A (mutant) + DNA + nucleotide derivative
    
  • 6s1c, 6s2e, 6s2f - yDpo II  subunit A (mutant) + DCC1 + chromosome transmission fidelity proteins
    
  • 6hv9 - yDpo II  subunit A+B + CMG + DNA + nucleotide – Cryo EM
    
  • 2r8j, 2r8k, 4ptf - yDpo  catalytic domain + DNA + nucleotide 
    
  • 6h1v - yDpo  catalytic domain (mutant) + DNA + nucleotide 
    
  • 2xgp, 2xgq, 2wtf - yDpo  + DNA
    
  • 7lxd - yDpo  catalytic+processivity subunits + hDpo d subunits 3+small – Cryo EM
    
  • 7s0t - yDpo  catalytic+processivity subunits + hDpo d subunits 3+small + DNA – Cryo EM
    
  • 5y27, 5y26 - Dpo subunit D + transcription factor – fission yeast
    
  • 1jih, 5vtp – yDpo catalytic domain
    

• DNA polymerase Rev1; Domains – BRCT 44-133; catalytic 330-833; UBM2 998-1040; C-terminal 1158-1251

• • 3gqc – hRev1 catalytic domain + DNA + nucleotide
    
  • 2ebw – hRev1 BRCT domain – NMR
    
  • 6axd – hRev1 UBM2 domain – NMR
    
  • 6asr – hRev1 UBM2 domain + ubiquitin
    
  • 5vzm – hRev1 UBM2 domain + ubiquitin - NMR
    
  • 2lsg, 2lsy – hRev1 C-terminal domain – NMR
    
  • 2n1g – hRev1 C-terminal domain + Dpo d subunit 3 – NMR
    
  • 2lsi – hRev1 C-terminal domain + hDpo  peptide
    
  • 2lsk – hRev1 C-terminal domain + hDpo  peptide
    
  • 4ext – hRev1 C-terminal domain + hDpo  catalytic subunit peptide + MAD2B
    
  • 4gk5 – hRev1 C-terminal domain + hDpo  peptide + hDpo  catalytic subunit peptide + MAD2B
    
  • 2lsj – mRev1 C-terminal domain + mDpo  peptide
    
  • 4fjo – mRev1 C-terminal domain + mDpo  peptide + MAD2B
    
  • 4id3, 5umv – yRev1 BRCT domain
    
  • 2m2i, 5vx7 – yRev1 BRCT domain – NMR
    
  • 6x70, 6x72, 6x73, 6x74, 6x76 – yRev1 catalytic domain + DNA
    
  • 3bjy, 2aq4, 3osp, 5wm1, 5wm8, 5wmb, 6x6z, 6x71, 6x75, 6x77 – yRev1 catalytic domain + DNA + nucleotide
    

 Terminal deoxynucleotidyl transferase

• • 2coe – TdT BRCT domain – NMR
    
  • 1jms – mTdT catalytic domain + Mg
    

Terminal deoxynucleotidyl transferase binary complex

• • 4iqt, 4iqu, 4iqv, 4iqw – mTdT catalytic domain + inhibitor
    
  • 4i2i – mTdT catalytic domain + Mg + Zn + adenosine-pentaphosphate
    
  • 4i2j – mTdT catalytic domain + CTP + Zn
    
  • 1kej – mTdT catalytic domain + ATP derivative + Co
    
  • 4i2d – mTdT catalytic domain + ATP derivative + Mg
    
  • 4i29 – mTdT catalytic domain + AMP derivative + Mn
    
  • 4i2b – mTdT catalytic domain + AMPCPP + Mg
    
  • 4i2c – mTdT catalytic domain + AMPCPP + Mn
    
  • 4i2a – mTdT catalytic domain + UMP derivative + Mg
    

Terminal deoxynucleotidyl transferase ternary complex with DNA

• • 4i2e – mTdT catalytic domain + AMPCPP + Co + DNA
    
  • 4i2h – mTdT catalytic domain + AMPCPP + Zn + Mg + DNA
    
  • 4i27 – mTdT catalytic domain + TTP derivative + TMP + Mg + DNA
    
  • 1kdh – mTdT catalytic domain + UMP derivative + Mg + DNA
    
  • 4i28, 4i2f – mTdT catalytic domain + Mg + Zn + DNA
    
  • 4i2g – mTdT catalytic domain + Mg + Co + DNA
    

}}