8rqt

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Current revision (06:16, 29 January 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8rqt is ON HOLD until 2026-01-19
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==Crystal structure of Pichia pastoris Pex8==
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<StructureSection load='8rqt' size='340' side='right'caption='[[8rqt]], [[Resolution|resolution]] 2.41&Aring;' scene=''>
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Authors: Ekal, L., Burgi, J., Chojnowski, G., WIlmanns, M.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8rqt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Komagataella_pastoris Komagataella pastoris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8RQT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8RQT FirstGlance]. <br>
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Description: Crystal structure of Pichia pastoris Pex8
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.41&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8rqt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8rqt OCA], [https://pdbe.org/8rqt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8rqt RCSB], [https://www.ebi.ac.uk/pdbsum/8rqt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8rqt ProSAT]</span></td></tr>
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[[Category: Chojnowski, G]]
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</table>
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[[Category: Burgi, J]]
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== Function ==
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[[Category: Wilmanns, M]]
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[https://www.uniprot.org/uniprot/PEX8_PICPA PEX8_PICPA] Essential component of the machinery required for the import of both PTS1 and PTS2 (and perhaps all) peroxisomal matrix proteins (PubMed:7738036). Binding of PEX8 to the N-terminus of PEX5 cargo receptor induces a conformational change of the TPR domains and decrease their binding affinity to cargo, facilitating the release of the PTS1 proteins within the peroxisome (PubMed:23902771).<ref>PMID:23902771</ref> <ref>PMID:7738036</ref>
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[[Category: Ekal, L]]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Komagataella pastoris]]
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[[Category: Large Structures]]
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[[Category: Burgi J]]
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[[Category: Chojnowski G]]
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[[Category: Ekal L]]
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[[Category: WIlmanns M]]

Current revision

Crystal structure of Pichia pastoris Pex8

PDB ID 8rqt

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