Death-associated protein
From Proteopedia
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'''Death-associated protein''' (DAP) or '''death domain-associated protein''' is associated with multiple cellular functions. | '''Death-associated protein''' (DAP) or '''death domain-associated protein''' is associated with multiple cellular functions. | ||
| + | *'''DAP3''' is known as mitochondrial small subunit ribosomal protein S29. Over-expression of DAP3 induces apoptosis in several cell lines.<ref>PMID:20079882</ref> | ||
*'''DAP6''' or Daxx interacts with apoptosis antigen. It has both pro- and anti-apoptosis functions.<ref>PMID:9215629</ref> | *'''DAP6''' or Daxx interacts with apoptosis antigen. It has both pro- and anti-apoptosis functions.<ref>PMID:9215629</ref> | ||
*'''DAP5''' is an inhibitor of translational initiation in differentiation and apoptosis. For more details on DAP5 see [[Death Associated Protein 5]]. | *'''DAP5''' is an inhibitor of translational initiation in differentiation and apoptosis. For more details on DAP5 see [[Death Associated Protein 5]]. | ||
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References
- ↑ Han MJ, Chiu DT, Koc EC. Regulation of mitochondrial ribosomal protein S29 (MRPS29) expression by a 5'-upstream open reading frame. Mitochondrion. 2010 Apr;10(3):274-83. PMID:20079882 doi:10.1016/j.mito.2009.12.150
- ↑ Yang X, Khosravi-Far R, Chang HY, Baltimore D. Daxx, a novel Fas-binding protein that activates JNK and apoptosis. Cell. 1997 Jun 27;89(7):1067-76. PMID:9215629
