Synthetic nanomaterials from standardized protein blocks
From Proteopedia
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==Building Blocks== | ==Building Blocks== | ||
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In this project, the simplest building blocks consist of anti-parallel alpha helices engineered to be straight and flat, that is ''twistless helix repeat'' (THR) protein blocks. A simple example, THR1, is [[8g9j]], consisting of <scene name='10/1068508/8g9j_flat_square/1'>eight anti-parallel alpha helices with seven turns per helix</scene>. | In this project, the simplest building blocks consist of anti-parallel alpha helices engineered to be straight and flat, that is ''twistless helix repeat'' (THR) protein blocks. A simple example, THR1, is [[8g9j]], consisting of <scene name='10/1068508/8g9j_flat_square/1'>eight anti-parallel alpha helices with seven turns per helix</scene>. | ||
Revision as of 02:23, 4 January 2025
This page is under construction. This notice will be removed when it is ready. Eric Martz 21:20, 23 December 2024 (UTC) |
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References
- ↑ 1.0 1.1 1.2 Huddy TF, Hsia Y, Kibler RD, Xu J, Bethel N, Nagarajan D, Redler R, Leung PJY, Weidle C, Courbet A, Yang EC, Bera AK, Coudray N, Calise SJ, Davila-Hernandez FA, Han HL, Carr KD, Li Z, McHugh R, Reggiano G, Kang A, Sankaran B, Dickinson MS, Coventry B, Brunette TJ, Liu Y, Dauparas J, Borst AJ, Ekiert D, Kollman JM, Bhabha G, Baker D. Blueprinting extendable nanomaterials with standardized protein blocks. Nature. 2024 Mar;627(8005):898-904. PMID:38480887 doi:10.1038/s41586-024-07188-4
- ↑ Wang S, Favor A, Kibler R, Lubner J, Borst AJ, Coudray N, Redler RL, Chiang HT, Sheffler W, Hsia Y, Li Z, Ekiert DC, Bhabha G, Pozzo LD, Baker D. Bond-centric modular design of protein assemblies. bioRxiv [Preprint]. 2024 Oct 12:2024.10.11.617872. PMID:39416012 doi:10.1101/2024.10.11.617872
