Synthetic nanomaterials from standardized protein blocks
From Proteopedia
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* <scene name='10/1068508/Tetrahedron_8tl7_cao/1'>Tetrahedron with ring faces: each face is a three-block ring with three arms; 12 blocks, one sequence</scene> ([[8tl7|8TL7]], 4.1 Å [[cryo-EM]]). | * <scene name='10/1068508/Tetrahedron_8tl7_cao/1'>Tetrahedron with ring faces: each face is a three-block ring with three arms; 12 blocks, one sequence</scene> ([[8tl7|8TL7]], 4.1 Å [[cryo-EM]]). | ||
* <scene name='10/1068508/Cube_no_vertices/1'>Cube with no vertices, 24 blocks, one sequence</scene> (cage_O4_32_design). | * <scene name='10/1068508/Cube_no_vertices/1'>Cube with no vertices, 24 blocks, one sequence</scene> (cage_O4_32_design). | ||
| - | * Cube with ring faces, 48 blocks, two sequences ([[8v2d]], 6.8 Å [[cryo-EM]], ''the initial scene''). | + | * <scene name='10/1068508/8v2d/2'>Cube with ring faces, 48 blocks, two sequences</scene> ([[8v2d]], 6.8 Å [[cryo-EM]], ''the initial scene''). |
==Related Work== | ==Related Work== | ||
Revision as of 23:35, 4 January 2025
This page is under construction. This notice will be removed when it is ready. Eric Martz 21:20, 23 December 2024 (UTC) |
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References
- ↑ 1.0 1.1 1.2 1.3 Huddy TF, Hsia Y, Kibler RD, Xu J, Bethel N, Nagarajan D, Redler R, Leung PJY, Weidle C, Courbet A, Yang EC, Bera AK, Coudray N, Calise SJ, Davila-Hernandez FA, Han HL, Carr KD, Li Z, McHugh R, Reggiano G, Kang A, Sankaran B, Dickinson MS, Coventry B, Brunette TJ, Liu Y, Dauparas J, Borst AJ, Ekiert D, Kollman JM, Bhabha G, Baker D. Blueprinting extendable nanomaterials with standardized protein blocks. Nature. 2024 Mar;627(8005):898-904. PMID:38480887 doi:10.1038/s41586-024-07188-4
- ↑ An amino-terminal histidine tag was not resolved in the electron density map of 8g9j, and thus is missing in the structure depicted.
- ↑ The five modules shown are from the following assemblies that can be downloaded as PDB files from supplementary materials of Huddy et al,, 2024: 90° from strut_C6_16. Branch from TT_rail+_tie+. Curve from R20A. Handshake 90° from cage_O4_32. Handshake obtuse angle from cage_I3_8.
- ↑ The assemblies shown can be downloaded as PDB files from supplementary materials of Huddy et al,, 2024.
- ↑ Wang S, Favor A, Kibler R, Lubner J, Borst AJ, Coudray N, Redler RL, Chiang HT, Sheffler W, Hsia Y, Li Z, Ekiert DC, Bhabha G, Pozzo LD, Baker D. Bond-centric modular design of protein assemblies. bioRxiv [Preprint]. 2024 Oct 12:2024.10.11.617872. PMID:39416012 doi:10.1101/2024.10.11.617872
