1u71
From Proteopedia
(Difference between revisions)
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| - | {{Seed}} | ||
[[Image:1u71.png|left|200px]] | [[Image:1u71.png|left|200px]] | ||
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{{ABSTRACT_PUBMED_15681865}} | {{ABSTRACT_PUBMED_15681865}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Anemia, megaloblastic, due to DHFR deficiency (1) OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=126060 126060]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[1u71]] is a 1 chain structure of [[Dihydrofolate reductase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U71 OCA]. | |
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| + | ==See Also== | ||
| + | *[[Dihydrofolate reductase]] | ||
==Reference== | ==Reference== | ||
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[[Category: Pangborn, W.]] | [[Category: Pangborn, W.]] | ||
[[Category: Human dhfr l22r variant]] | [[Category: Human dhfr l22r variant]] | ||
| - | + | [[Category: Oxidoreductase]] | |
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Revision as of 19:47, 26 December 2010
Contents |
Understanding the Role of Leu22 Variants in Methotrexate Resistance: Comparison of Wild-type and Leu22Arg Variant Mouse and Human Dihydrofolate Reductase Ternary Crystal Complexes with Methotrexate and NADPH
Template:ABSTRACT PUBMED 15681865
About this Structure
1u71 is a 1 chain structure of Dihydrofolate reductase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Cody V, Luft JR, Pangborn W. Understanding the role of Leu22 variants in methotrexate resistance: comparison of wild-type and Leu22Arg variant mouse and human dihydrofolate reductase ternary crystal complexes with methotrexate and NADPH. Acta Crystallogr D Biol Crystallogr. 2005 Feb;61(Pt 2):147-55. Epub 2005, Jan 19. PMID:15681865 doi:http://dx.doi.org/10.1107/S0907444904030422
