1ia3
From Proteopedia
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===Candida albicans dihydrofolate reductase complex in which the dihydronicotinamide moiety of dihydro-nicotinamide-adenine-dinucleotide phosphate (NADPH) is displaced by 5-[(4-TERT-BUTYLPHENYL)SULFANYL]-2,4-QUINAZOLINEDIAMINE (GW995)=== | ===Candida albicans dihydrofolate reductase complex in which the dihydronicotinamide moiety of dihydro-nicotinamide-adenine-dinucleotide phosphate (NADPH) is displaced by 5-[(4-TERT-BUTYLPHENYL)SULFANYL]-2,4-QUINAZOLINEDIAMINE (GW995)=== | ||
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==About this Structure== | ==About this Structure== | ||
- | + | [[1ia3]] is a 2 chain structure of [[Dihydrofolate reductase]] with sequence from [http://en.wikipedia.org/wiki/Candida_albicans Candida albicans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IA3 OCA]. | |
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+ | ==See Also== | ||
+ | *[[Dihydrofolate reductase|Dihydrofolate reductase]] | ||
==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:011520201</ref><references group="xtra"/> |
[[Category: Candida albicans]] | [[Category: Candida albicans]] | ||
[[Category: Dihydrofolate reductase]] | [[Category: Dihydrofolate reductase]] | ||
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[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
[[Category: Reductase]] | [[Category: Reductase]] | ||
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Revision as of 04:59, 26 July 2012
Contents |
Candida albicans dihydrofolate reductase complex in which the dihydronicotinamide moiety of dihydro-nicotinamide-adenine-dinucleotide phosphate (NADPH) is displaced by 5-[(4-TERT-BUTYLPHENYL)SULFANYL]-2,4-QUINAZOLINEDIAMINE (GW995)
Template:ABSTRACT PUBMED 11520201
About this Structure
1ia3 is a 2 chain structure of Dihydrofolate reductase with sequence from Candida albicans. Full crystallographic information is available from OCA.
See Also
Reference
- Whitlow M, Howard AJ, Stewart D, Hardman KD, Chan JH, Baccanari DP, Tansik RL, Hong JS, Kuyper LF. X-Ray crystal structures of Candida albicans dihydrofolate reductase: high resolution ternary complexes in which the dihydronicotinamide moiety of NADPH is displaced by an inhibitor. J Med Chem. 2001 Aug 30;44(18):2928-32. PMID:11520201