1sej
From Proteopedia
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===Crystal Structure of Dihydrofolate Reductase-Thymidylate Synthase from Cryptosporidium hominis Bound to 1843U89/NADPH/dUMP=== | ===Crystal Structure of Dihydrofolate Reductase-Thymidylate Synthase from Cryptosporidium hominis Bound to 1843U89/NADPH/dUMP=== | ||
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{{ABSTRACT_PUBMED_16511011}} | {{ABSTRACT_PUBMED_16511011}} | ||
==About this Structure== | ==About this Structure== | ||
- | + | [[1sej]] is a 5 chain structure of [[Dihydrofolate reductase]] and [[Thymidylate synthase]] with sequence from [http://en.wikipedia.org/wiki/Cryptosporidium_hominis Cryptosporidium hominis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SEJ OCA]. | |
+ | |||
+ | ==See Also== | ||
+ | *[[Dihydrofolate reductase|Dihydrofolate reductase]] | ||
+ | *[[Thymidylate synthase|Thymidylate synthase]] | ||
==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:016511011</ref><references group="xtra"/> |
[[Category: Cryptosporidium hominis]] | [[Category: Cryptosporidium hominis]] | ||
[[Category: Anderson, A C.]] | [[Category: Anderson, A C.]] | ||
[[Category: Bifunctional enzyme]] | [[Category: Bifunctional enzyme]] | ||
- | + | [[Category: Oxidoreductase]] | |
- | + | [[Category: Transferase]] |
Revision as of 15:31, 27 July 2012
Contents |
Crystal Structure of Dihydrofolate Reductase-Thymidylate Synthase from Cryptosporidium hominis Bound to 1843U89/NADPH/dUMP
Template:ABSTRACT PUBMED 16511011
About this Structure
1sej is a 5 chain structure of Dihydrofolate reductase and Thymidylate synthase with sequence from Cryptosporidium hominis. Full crystallographic information is available from OCA.
See Also
Reference
- Anderson AC. Two crystal structures of dihydrofolate reductase-thymidylate synthase from Cryptosporidium hominis reveal protein-ligand interactions including a structural basis for observed antifolate resistance. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 Mar 1;61(Pt, 3):258-62. Epub 2005 Feb 8. PMID:16511011 doi:10.1107/S1744309105002435