This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1sej
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | {{Seed}} | ||
[[Image:1sej.png|left|200px]] | [[Image:1sej.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_1sej", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_1sej| PDB=1sej | SCENE= }} | {{STRUCTURE_1sej| PDB=1sej | SCENE= }} | ||
===Crystal Structure of Dihydrofolate Reductase-Thymidylate Synthase from Cryptosporidium hominis Bound to 1843U89/NADPH/dUMP=== | ===Crystal Structure of Dihydrofolate Reductase-Thymidylate Synthase from Cryptosporidium hominis Bound to 1843U89/NADPH/dUMP=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_16511011}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 16511011 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_16511011}} | {{ABSTRACT_PUBMED_16511011}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[1sej]] is a 5 chain structure of [[Dihydrofolate reductase]] and [[Thymidylate synthase]] with sequence from [http://en.wikipedia.org/wiki/Cryptosporidium_hominis Cryptosporidium hominis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SEJ OCA]. | |
| + | |||
| + | ==See Also== | ||
| + | *[[Dihydrofolate reductase|Dihydrofolate reductase]] | ||
| + | *[[Thymidylate synthase|Thymidylate synthase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:016511011</ref><references group="xtra"/> |
[[Category: Cryptosporidium hominis]] | [[Category: Cryptosporidium hominis]] | ||
[[Category: Anderson, A C.]] | [[Category: Anderson, A C.]] | ||
[[Category: Bifunctional enzyme]] | [[Category: Bifunctional enzyme]] | ||
| - | + | [[Category: Oxidoreductase]] | |
| - | + | [[Category: Transferase]] | |
Revision as of 15:31, 27 July 2012
Contents |
Crystal Structure of Dihydrofolate Reductase-Thymidylate Synthase from Cryptosporidium hominis Bound to 1843U89/NADPH/dUMP
Template:ABSTRACT PUBMED 16511011
About this Structure
1sej is a 5 chain structure of Dihydrofolate reductase and Thymidylate synthase with sequence from Cryptosporidium hominis. Full crystallographic information is available from OCA.
See Also
Reference
- Anderson AC. Two crystal structures of dihydrofolate reductase-thymidylate synthase from Cryptosporidium hominis reveal protein-ligand interactions including a structural basis for observed antifolate resistance. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 Mar 1;61(Pt, 3):258-62. Epub 2005 Feb 8. PMID:16511011 doi:10.1107/S1744309105002435
