G3p
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Overview== | ==Overview== | ||
| - | Gene 3 protein (g3p pr pIII) is a minor coat protein found on the surface of filamentous bacteriophage <ref name="lubkowski"> PMID:9461080 </ref>. The protein consists of 406 amino acids divided into three domains interspaced with glycine linkers <ref name="lubkowski"/> <ref name="cabilly"> PMID:10596371 </ref>. Peptides or proteins can be fused to g3p and evaluated for binding or other properties | + | [[Image:wt_and_pIII.jpg |frame|right|Figure Adapted from Hill and Stockley et al, 1996 <ref name="hill"> PMID:8793867 </ref>]] |
| + | Gene 3 protein (g3p pr pIII) is a minor coat protein found on the surface of filamentous bacteriophage <ref name="lubkowski"> PMID:9461080 </ref>. The protein consists of 406 amino acids divided into three domains interspaced with glycine linkers <ref name="lubkowski"/> <ref name="cabilly"> PMID:10596371 </ref>. Peptides or proteins can be fused to g3p and evaluated for binding or other properties. | ||
| + | |||
| - | {{STRUCTURE_2g3p | PDB=2g3p | SCENE= }} | ||
===Structural Analysis=== | ===Structural Analysis=== | ||
Information regarding structure of g3p goes here. | Information regarding structure of g3p goes here. | ||
| - | + | {{STRUCTURE_2g3p | PDB=2g3p | SCENE= }} | |
===Functional Implications=== | ===Functional Implications=== | ||
The relationship between domains and infectivity goes here. | The relationship between domains and infectivity goes here. | ||
Revision as of 01:53, 28 April 2009
Contents |
Overview
Image:Wt and pIII.jpg
Figure Adapted from Hill and Stockley et al, 1996 [1]
Gene 3 protein (g3p pr pIII) is a minor coat protein found on the surface of filamentous bacteriophage [2]. The protein consists of 406 amino acids divided into three domains interspaced with glycine linkers [2] [3]. Peptides or proteins can be fused to g3p and evaluated for binding or other properties.
Structural Analysis
Information regarding structure of g3p goes here. Template:STRUCTURE 2g3p
Functional Implications
The relationship between domains and infectivity goes here.
Evolutionarily Related Proteins
This is a placeholder text to help you get started in placing a Jmol applet on your page. At any time, click "Show Preview" at the bottom of this page to see how it goes.
References
- ↑ Hill HR, Stockley PG. Phage presentation. Mol Microbiol. 1996 May;20(4):685-92. PMID:8793867 doi:10.1111/j.1365-2958.1996.tb02508.x
- ↑ 2.0 2.1 Lubkowski J, Hennecke F, Pluckthun A, Wlodawer A. The structural basis of phage display elucidated by the crystal structure of the N-terminal domains of g3p. Nat Struct Biol. 1998 Feb;5(2):140-7. PMID:9461080
- ↑ Cabilly S. The basic structure of filamentous phage and its use in the display of combinatorial peptide libraries. Mol Biotechnol. 1999 Sep;12(2):143-8. PMID:10596371 doi:10.1385/MB:12:2:143
