3cxc
From Proteopedia
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{{STRUCTURE_3cxc| PDB=3cxc | SCENE= }} | {{STRUCTURE_3cxc| PDB=3cxc | SCENE= }} | ||
===The structure of an enhanced oxazolidinone inhibitor bound to the 50S ribosomal subunit of H. marismortui=== | ===The structure of an enhanced oxazolidinone inhibitor bound to the 50S ribosomal subunit of H. marismortui=== | ||
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{{ABSTRACT_PUBMED_18947996}} | {{ABSTRACT_PUBMED_18947996}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3cxc]] is a 30 chain structure of [[Ribosomal protein L10]], [[Ribosomal protein L13]], [[Ribosomal protein L14]], [[Ribosomal protein L15]], [[Ribosomal protein L18]], [[Ribosomal protein L19]], [[Ribosomal protein L2]], [[Ribosomal protein L21]], [[Ribosomal protein L22]], [[Ribosomal protein L23]], [[Ribosomal protein L24]], [[Ribosomal protein L25]], [[Ribosomal protein L29]], [[Ribosomal protein L3]], [[Ribosomal protein L30]], [[Ribosomal protein L4]], [[Ribosomal protein L5]], [[Ribosomal protein L6]] and [[Ribosomal protein L7]] with sequence from [http://en.wikipedia.org/wiki/Haloarcula_marismortui Haloarcula marismortui]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CXC OCA]. | |
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| + | ==See Also== | ||
| + | *[[Ribosomal protein L10|Ribosomal protein L10]] | ||
| + | *[[Ribosomal protein L13|Ribosomal protein L13]] | ||
| + | *[[Ribosomal protein L14|Ribosomal protein L14]] | ||
| + | *[[Ribosomal protein L15|Ribosomal protein L15]] | ||
| + | *[[Ribosomal protein L18|Ribosomal protein L18]] | ||
| + | *[[Ribosomal protein L19|Ribosomal protein L19]] | ||
| + | *[[Ribosomal protein L2|Ribosomal protein L2]] | ||
| + | *[[Ribosomal protein L21|Ribosomal protein L21]] | ||
| + | *[[Ribosomal protein L22|Ribosomal protein L22]] | ||
| + | *[[Ribosomal protein L23|Ribosomal protein L23]] | ||
| + | *[[Ribosomal protein L24|Ribosomal protein L24]] | ||
| + | *[[Ribosomal protein L25|Ribosomal protein L25]] | ||
| + | *[[Ribosomal protein L29|Ribosomal protein L29]] | ||
| + | *[[Ribosomal protein L3|Ribosomal protein L3]] | ||
| + | *[[Ribosomal protein L30|Ribosomal protein L30]] | ||
| + | *[[Ribosomal protein L4|Ribosomal protein L4]] | ||
| + | *[[Ribosomal protein L5|Ribosomal protein L5]] | ||
| + | *[[Ribosomal protein L6|Ribosomal protein L6]] | ||
| + | *[[Ribosomal protein L7|Ribosomal protein L7]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018947996</ref><references group="xtra"/> |
[[Category: Haloarcula marismortui]] | [[Category: Haloarcula marismortui]] | ||
[[Category: Duffy, E M.]] | [[Category: Duffy, E M.]] | ||
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[[Category: Oxazolidinone]] | [[Category: Oxazolidinone]] | ||
[[Category: Ribosome]] | [[Category: Ribosome]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 6 10:51:58 2009'' | ||
Revision as of 19:13, 26 July 2012
Contents |
The structure of an enhanced oxazolidinone inhibitor bound to the 50S ribosomal subunit of H. marismortui
Template:ABSTRACT PUBMED 18947996
About this Structure
3cxc is a 30 chain structure of Ribosomal protein L10, Ribosomal protein L13, Ribosomal protein L14, Ribosomal protein L15, Ribosomal protein L18, Ribosomal protein L19, Ribosomal protein L2, Ribosomal protein L21, Ribosomal protein L22, Ribosomal protein L23, Ribosomal protein L24, Ribosomal protein L25, Ribosomal protein L29, Ribosomal protein L3, Ribosomal protein L30, Ribosomal protein L4, Ribosomal protein L5, Ribosomal protein L6 and Ribosomal protein L7 with sequence from Haloarcula marismortui. Full crystallographic information is available from OCA.
See Also
- Ribosomal protein L10
- Ribosomal protein L13
- Ribosomal protein L14
- Ribosomal protein L15
- Ribosomal protein L18
- Ribosomal protein L19
- Ribosomal protein L2
- Ribosomal protein L21
- Ribosomal protein L22
- Ribosomal protein L23
- Ribosomal protein L24
- Ribosomal protein L25
- Ribosomal protein L29
- Ribosomal protein L3
- Ribosomal protein L30
- Ribosomal protein L4
- Ribosomal protein L5
- Ribosomal protein L6
- Ribosomal protein L7
Reference
- Zhou J, Bhattacharjee A, Chen S, Chen Y, Duffy E, Farmer J, Goldberg J, Hanselmann R, Ippolito JA, Lou R, Orbin A, Oyelere A, Salvino J, Springer D, Tran J, Wang D, Wu Y, Johnson G. Design at the atomic level: design of biaryloxazolidinones as potent orally active antibiotics. Bioorg Med Chem Lett. 2008 Dec 1;18(23):6175-8. Epub 2008 Oct 7. PMID:18947996 doi:10.1016/j.bmcl.2008.10.011
