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User:Tommie Hata/Introduction to Protein Engineering-Subtilisin
From Proteopedia
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This Protein Engineering module has been developed using material from [http://www.cheme.columbia.edu/fac-bios/banta/faculty.html Dr. Scott Banta's] course, Protein Engineering ([http://www.cheme.columbia.edu/index.html chemical engineering department at Columbia University]). | This Protein Engineering module has been developed using material from [http://www.cheme.columbia.edu/fac-bios/banta/faculty.html Dr. Scott Banta's] course, Protein Engineering ([http://www.cheme.columbia.edu/index.html chemical engineering department at Columbia University]). | ||
| - | <applet load='2sic' size='400' frame='true' align='right' caption='PDB ID 2sic, Subtilisin BPN' scene='User:Tommie_Hata/Introduction_to_Protein_Engineering-Subtilisin/Default/1'/> | + | <applet load='2sic' size='400' frame='true' align='right' caption='PDB ID 2sic, Subtilisin BPN' scene='User:Tommie_Hata/Introduction_to_Protein_Engineering-Subtilisin/Default-whole/1'/> |
The enzyme to the right is subtilisin BPN' from PDB file 2sic. The structure includes the ''Streptomyces'' subtilisin inhibitor, which has been minimized in the view to highlight the chain bound in the active site of subtilisin. | The enzyme to the right is subtilisin BPN' from PDB file 2sic. The structure includes the ''Streptomyces'' subtilisin inhibitor, which has been minimized in the view to highlight the chain bound in the active site of subtilisin. | ||
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| + | <scene name='User:Tommie_Hata/Introduction_to_Protein_Engineering-Subtilisin/Default/1'>TextToBeDisplayed</scene> | ||
<scene name='User:Tommie_Hata/Introduction_to_Protein_Engineering-Subtilisin/Remove_inhibitor/1'>TextToBeDisplayed</scene> | <scene name='User:Tommie_Hata/Introduction_to_Protein_Engineering-Subtilisin/Remove_inhibitor/1'>TextToBeDisplayed</scene> | ||
Revision as of 14:30, 6 August 2009
This Protein Engineering module has been developed using material from Dr. Scott Banta's course, Protein Engineering (chemical engineering department at Columbia University).
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The enzyme to the right is subtilisin BPN' from PDB file 2sic. The structure includes the Streptomyces subtilisin inhibitor, which has been minimized in the view to highlight the chain bound in the active site of subtilisin.
Reference
- Takeuchi Y, Satow Y, Nakamura KT, Mitsui Y. Refined crystal structure of the complex of subtilisin BPN' and Streptomyces subtilisin inhibitor at 1.8 A resolution. J Mol Biol. 1991 Sep 5;221(1):309-25. PMID:1920411
