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Group:SMART:2010 Pingry SMART Team Models
From Proteopedia
(Difference between revisions)
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== AdhD K249G/H255R double mutant and Self-assembly into hydrogels == | == AdhD K249G/H255R double mutant and Self-assembly into hydrogels == | ||
<applet load='AdhD_with_three_cofactors_no_H.pdb' size='400' frame='true' align='left' caption='AdhD K249G/H255R double mutant' scene='2010_Pingry_SMART_Team/Adhd_0/2'/> | <applet load='AdhD_with_three_cofactors_no_H.pdb' size='400' frame='true' align='left' caption='AdhD K249G/H255R double mutant' scene='2010_Pingry_SMART_Team/Adhd_0/2'/> | ||
| - | <scene name='2010_Pingry_SMART_Team/Adhd_0/3'>Show NAD</scene> | ||
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| - | <scene name='2010_Pingry_SMART_Team/Adhd_0/4'>Show NADP</scene> | ||
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| - | <scene name='2010_Pingry_SMART_Team/Adhd_0/5'>Show nicotimanide</scene> | ||
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| - | <scene name='2010_Pingry_SMART_Team/Adhd_0/2'>Remove cofactor</scene> | ||
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==PDB ID: 1a80, 2,5-diketo-d-gluconic acid reductase with NADPH (wild-type)== | ==PDB ID: 1a80, 2,5-diketo-d-gluconic acid reductase with NADPH (wild-type)== | ||
<applet load='1a80' size='400' frame='true' align='left' caption='1a80, 2,5-diketo-d-gluconic acid reductase with NADPH (wild-type)' scene='2010_Pingry_SMART_Team/1a80-original/22'/> | <applet load='1a80' size='400' frame='true' align='left' caption='1a80, 2,5-diketo-d-gluconic acid reductase with NADPH (wild-type)' scene='2010_Pingry_SMART_Team/1a80-original/22'/> | ||
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| - | '''Design description''' | ||
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| - | 2,5-DKGR A possesses a parallel alpha-beta structural motif of the <scene name='2010_Pingry_SMART_Team/1a80-default/2'>eight alpha helices (highlighted red) and eight beta strands (highlighted blue)</scene> found in all enzymes in the aldo-keto reductase(AKR) family. | ||
{{Clear}} | {{Clear}} | ||
| + | ==PDB ID: 1m9h, Mutant 2,5-diketo-d-gluconic acid reductase with NADH (mutant)== | ||
<applet load='1m9h' size='400' frame='true' align='left' caption='1m9h, Mutant 2,5-diketo-d-gluconic acid reductase with NADH' scene='2010_Pingry_SMART_Team/1m9h_default/1'/> | <applet load='1m9h' size='400' frame='true' align='left' caption='1m9h, Mutant 2,5-diketo-d-gluconic acid reductase with NADH' scene='2010_Pingry_SMART_Team/1m9h_default/1'/> | ||
| - | |||
| - | ==PDB ID: 1m9h, Mutant 2,5-diketo-d-gluconic acid reductase with NADH (mutant)== | ||
{{Clear}} | {{Clear}} | ||
| - | == | + | ==PDB ID: 1k8c, Xylose reductase with NADP+== |
<applet load='1K8C_chainD.pdb' size='400' frame='true' align='left' caption='1k8c, Xylose reductase with NADP+' scene='2010_Pingry_SMART_Team/1k8c_nospindefault/1'/> | <applet load='1K8C_chainD.pdb' size='400' frame='true' align='left' caption='1k8c, Xylose reductase with NADP+' scene='2010_Pingry_SMART_Team/1k8c_nospindefault/1'/> | ||
| - | + | ||
| + | {{Clear}} | ||
| + | |||
| + | ==PDB ID: 1mi3, Xylose reductase with NAD+== | ||
<applet load='1MI3_chainA.pdb' size='400' frame='true' align='left' caption='1mi3, Xylose reductase with NAD+' scene='2010_Pingry_SMART_Team/1mi3_nospindefault/1'/> | <applet load='1MI3_chainA.pdb' size='400' frame='true' align='left' caption='1mi3, Xylose reductase with NAD+' scene='2010_Pingry_SMART_Team/1mi3_nospindefault/1'/> | ||
| - | + | {{Clear}} | |
| - | + | ==PDB ID: 1lwi, Rat liver 3-alpha-hydroxysteroid dihydrodiol dehydrogenase with NADP+ cofactor== | |
| - | == | + | |
| - | + | ||
<applet load='1LWI_chainA.pdb' size='400' frame='true' align='left' caption='1lwi, Rat liver 3-alpha-hydroxysteroid dihydrodiol dehydrogenase with NADP+ cofactor' scene='2010_Pingry_SMART_Team/1lwi_default/7'/> | <applet load='1LWI_chainA.pdb' size='400' frame='true' align='left' caption='1lwi, Rat liver 3-alpha-hydroxysteroid dihydrodiol dehydrogenase with NADP+ cofactor' scene='2010_Pingry_SMART_Team/1lwi_default/7'/> | ||
| - | ====PDB ID: 1lwi, Rat liver 3-alpha-hydroxysteroid dihydrodiol dehydrogenase with NADP+ cofactor==== | ||
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| + | {{Clear}} | ||
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| + | ====PDB ID: 1afs, Rat liver 3-alpha-hydroxysteroid dihydrodiol dehydrogenase with cofactor and testosterone==== | ||
<applet load='1AFS_chainA.pdb' size='400' frame='true' align='left' caption='1afs, Rat liver 3-alpha-hydroxysteroid dihydrodiol dehydrogenase with cofactor and testosterone' scene='2010_Pingry_SMART_Team/1afs_default/7'/> | <applet load='1AFS_chainA.pdb' size='400' frame='true' align='left' caption='1afs, Rat liver 3-alpha-hydroxysteroid dihydrodiol dehydrogenase with cofactor and testosterone' scene='2010_Pingry_SMART_Team/1afs_default/7'/> | ||
| - | + | {{Clear}} | |
Revision as of 02:28, 8 March 2010
Return to 2010 SMART Team Page: 2010 Pingry SMART Team
AdhD K249G/H255R double mutant and Self-assembly into hydrogels
|
PDB ID: 1a80, 2,5-diketo-d-gluconic acid reductase with NADPH (wild-type)
|
PDB ID: 1m9h, Mutant 2,5-diketo-d-gluconic acid reductase with NADH (mutant)
|
PDB ID: 1k8c, Xylose reductase with NADP+
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PDB ID: 1mi3, Xylose reductase with NAD+
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PDB ID: 1lwi, Rat liver 3-alpha-hydroxysteroid dihydrodiol dehydrogenase with NADP+ cofactor
|
PDB ID: 1afs, Rat liver 3-alpha-hydroxysteroid dihydrodiol dehydrogenase with cofactor and testosterone
|
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Tommie Hata, Mai-Lee Picard, Ed Xiao, Florence Ma, Alexander Berchansky, Connie Wang, Jaime Prilusky, Dylan Sun
