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Ribosomal protein S2

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Line 12: Line 12:
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2zm6, 1n36, 1j5e - TtRPS2 in 30S ribosomal subunit+THX+16S RRNA – Thermus thermophilus
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[[2zm6]], [[1n36]], [[1j5e]] - TtRPS2 in 30S ribosomal subunit+THX+16S RRNA – Thermus thermophilus
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2vqe, 2vqf, 2uuc, 2e5l, 2uu9, 2uua, 2uub - TtRPS2 in 30S ribosomal subunit+16S RRNA+RNA fragment
+
[[2vqe]], [[2vqf]], [[2uuc]], [[2e5l]], [[2uu9]], [[2uua]], [[2uub]] - TtRPS2 in 30S ribosomal subunit+16S RRNA+RNA fragment
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3kc4 - EcRPS2 in 30S ribosomal subunit - Escherichia coli
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[[3kc4]] - EcRPS2 in 30S ribosomal subunit - Escherichia coli
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3i1m, 3i1o, 3df1, 3df3, 2vho, 2vhp, 2avy, 2aw7, 1pnx - EcRPS2 in 30S ribosomal subunit+16S RRNA
+
[[3i1m]], [[3i1o]], [[3df1]], [[3df3]], [[2vho]], [[2vhp]], [[2avy]], [[2aw7]], [[1pnx]] - EcRPS2 in 30S ribosomal subunit+16S RRNA
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1i94, 1fka - TtRPS2 in 30S ribosomal subunit+16S RRNA
+
[[1i94]], [[1fka]] - TtRPS2 in 30S ribosomal subunit+16S RRNA
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1p87 - EcRPS2 in 30S ribosomal subunit+16S RRNA – Cryo-EM
+
[[1p87]] - EcRPS2 in 30S ribosomal subunit+16S RRNA – Cryo-EM
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3bbn - RPS2 in 30S ribosomal subunit+16S RRNA – Cryo-EM – spinach
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[[3bbn]] - RPS2 in 30S ribosomal subunit+16S RRNA – Cryo-EM – spinach
Line 24: Line 24:
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1ml5 - EcRPS2 in 30S ribosomal subunit+50S ribosomal subunit+THX+chain release factor 2+P-site tRNA+tRNA Phe+mRNA fragment+23S RRNA+5S RRNA+16S RRNA - EM
+
[[1ml5]] - EcRPS2 in 30S ribosomal subunit+50S ribosomal subunit+THX+chain release factor 2+P-site tRNA+tRNA Phe+mRNA fragment+23S RRNA+5S RRNA+16S RRNA - EM
Line 30: Line 30:
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3mr8, 3ms0 – TtRPS2 in 30S ribosomal subunit+THX+chain release factor 1+P-site tRNA+mRNA+16S RRNA
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[[3mr8]], [[3ms0]] – TtRPS2 in 30S ribosomal subunit+THX+chain release factor 1+P-site tRNA+mRNA+16S RRNA
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3d5a, 3d5c - TtRPS2 in 30S ribosomal subunit+THX+chain release factor 1+P-site tRNA+E-site tRNA+mRNA +16S RRNA
+
[[3d5a]], [[3d5c]] - TtRPS2 in 30S ribosomal subunit+THX+chain release factor 1+P-site tRNA+E-site tRNA+mRNA +16S RRNA
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2b64 - TtRPS2 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA+chain release factor 1
+
[[2b64]] - TtRPS2 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA+chain release factor 1
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2b9m - TtRPS2 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA+chain release factor 2
+
[[2b9m]] - TtRPS2 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA+chain release factor 2
-
2x9r, 2x9t, 2wh1, 2wh3 - TtRPS2 in 30S ribosomal subunit+THX+chain release factor 2+P-site tRNA+mRNA +16S RRNA
+
[[2x9r]], [[2x9t]], [[2wh1]], [[2wh3]] - TtRPS2 in 30S ribosomal subunit+THX+chain release factor 2+P-site tRNA+mRNA +16S RRNA
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3f1e, 3f1g - TtRPS2 in 30S ribosomal subunit+THX+chain release factor 2+P-site tRNA+E-site tRNA +16S RRNA
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[[3f1e]], [[3f1g]] - TtRPS2 in 30S ribosomal subunit+THX+chain release factor 2+P-site tRNA+E-site tRNA +16S RRNA
Line 41: Line 41:
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2hgi - TtRPS2 in 30S ribosomal subunit+16S RRNA+tRNA Phe+tRNA fMet
+
[[2hgi]] - TtRPS2 in 30S ribosomal subunit+16S RRNA+tRNA Phe+tRNA fMet
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2hgp, 2i2p, 2i2u - TtRPS2 in 30S ribosomal subunit+16S RRNA+tRNA Phe+mRNA
+
[[2hgp]], [[2i2p]], [[2i2u]] - TtRPS2 in 30S ribosomal subunit+16S RRNA+tRNA Phe+mRNA
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2hgr - TtRPS2 in 30S ribosomal subunit+16S RRNA+tRNA Phe+tRNA fMet+mRNA
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[[2hgr]] - TtRPS2 in 30S ribosomal subunit+16S RRNA+tRNA Phe+tRNA fMet+mRNA
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1yl4 – TtRPS2 in 30S ribosomal subunit+ tRNA Phe+16S RRNA+THRS mRNA operator
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[[1yl4]] – TtRPS2 in 30S ribosomal subunit+ tRNA Phe+16S RRNA+THRS mRNA operator
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1pns - EcRPS2 in 30S ribosomal subunit+ tRNA Phe+16S RRNA+mRNA
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[[1pns]] - EcRPS2 in 30S ribosomal subunit+ tRNA Phe+16S RRNA+mRNA
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1xnq, 1xnr- TtRPS2 in 30S ribosomal subunit+THX+mRNA+tRNA anticodon+16S RRNA
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[[1xnq]], [[1xnr]]- TtRPS2 in 30S ribosomal subunit+THX+mRNA+tRNA anticodon+16S RRNA
Line 52: Line 52:
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2uxd , 2uxc- TtRPS2 in 30S ribosomal subunit+THX+A-site mRNA CGGG+tRNA anticodon+16S RRNA
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[[2uxd]], [[2uxc]] - TtRPS2 in 30S ribosomal subunit+THX+A-site mRNA CGGG+tRNA anticodon+16S RRNA
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1n32, 1n33 - TtRPS2 in 30S ribosomal subunit+THX+A-site mRNA fragment+tRNA anticodon+16S RRNA
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[[1n32]], [[1n33]] - TtRPS2 in 30S ribosomal subunit+THX+A-site mRNA fragment+tRNA anticodon+16S RRNA
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1n34 - TtRPS2 in 30S ribosomal subunit+THX+A-site mRNA fragment +16S RRNA
+
[[1n34]] - TtRPS2 in 30S ribosomal subunit+THX+A-site mRNA fragment +16S RRNA
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1xmo, 1xmq - TtRPS2 in 30S ribosomal subunit+THX+A-site mRNA+tRNA anticodon+16S RRNA
+
[[1xmo]], [[1xmq]] - TtRPS2 in 30S ribosomal subunit+THX+A-site mRNA+tRNA anticodon+16S RRNA
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2uxb - TtRPS2 in 30S ribosomal subunit+THX+A-site mRNA GGGU+tRNA anticodon+16S RRNA
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[[2uxb]] - TtRPS2 in 30S ribosomal subunit+THX+A-site mRNA GGGU+tRNA anticodon+16S RRNA
Line 62: Line 62:
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3i8g - TtRPS2 in 30S ribosomal subunit+P-site tRNA+mRNA +16S RRNA
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[[3i8g]] - TtRPS2 in 30S ribosomal subunit+P-site tRNA+mRNA +16S RRNA
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3i8h, 3i9b, 3i9d - TtRPS2 in 30S ribosomal subunit+THX+P-site tRNA+mRNA +16S RRNA
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[[3i8h]], [[3i9b]], [[3i9d]] - TtRPS2 in 30S ribosomal subunit+THX+P-site tRNA+mRNA +16S RRNA
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1ibk - TtRPS2 in 30S ribosomal subunit+THX+P-site mRNA fragment +16S RRNA
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[[1ibk]] - TtRPS2 in 30S ribosomal subunit+THX+P-site mRNA fragment +16S RRNA
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2wwl - EcRPS2 in 30S ribosomal subunit+Poly-Ala chain+P-site tRNA+mRNA +16S RRNA
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[[2wwl]] - EcRPS2 in 30S ribosomal subunit+Poly-Ala chain+P-site tRNA+mRNA +16S RRNA
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3i1q - EcRPS2 in 30S ribosomal subunit+P-site tRNA hairpin+mRNA
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[[3i1q]] - EcRPS2 in 30S ribosomal subunit+P-site tRNA hairpin+mRNA
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3i1s, 3i1z, 3i21 - EcRPS2 in 30S ribosomal subunit+P-site tRNA hairpin+mRNA +16S RNA
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[[3i1s]], [[3i1z]], [[3i21]] - EcRPS2 in 30S ribosomal subunit+P-site tRNA hairpin+mRNA +16S RNA
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2om7 – TtRPS2+TtRPS12+TtRPL1+ P-site tRNA+16S RRNA fragment+23S RRNA fragment
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[[2om7]] – TtRPS2+TtRPS12+TtRPL1+ P-site tRNA+16S RRNA fragment+23S RRNA fragment
Line 74: Line 74:
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1ibl, 1ibm - TtRPS2 in 30S ribosomal subunit+THX+A-site mRNA fragment+P-site mRNA fragment+tRNA anticodon+16S RRNA
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[[1ibl]], [[1ibm]] - TtRPS2 in 30S ribosomal subunit+THX+A-site mRNA fragment+P-site mRNA fragment+tRNA anticodon+16S RRNA
Line 80: Line 80:
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2ow8 - TtRPS2 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA+mRNA +16S RRNA
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[[2ow8]] - TtRPS2 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA+mRNA +16S RRNA
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2b9o - TtRPS2 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA
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[[2b9o]] - TtRPS2 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA
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2qnh - TtRPS2 in 30S ribosomal subunit+THX+P-site tRNA+E-site tRNA+mRNA +16S RRNA
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[[2qnh]] - TtRPS2 in 30S ribosomal subunit+THX+P-site tRNA+E-site tRNA+mRNA +16S RRNA
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2wdg, 2wdh, 2wdk, 2wdm - TtRPS2 in 30S ribosomal subunit+THX+P-site tRNA+E-site tRNA+mRNA +16S RRNA+tRNA Phe
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[[2wdg]], [[2wdh]], [[2wdk]], [[2wdm]] - TtRPS2 in 30S ribosomal subunit+THX+P-site tRNA+E-site tRNA+mRNA +16S RRNA+tRNA Phe
Line 89: Line 89:
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2gy9, 2gyb - EcRPS2 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA – Cryo-EM
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[[2gy9]], [[2gyb]] - EcRPS2 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA – Cryo-EM
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1jgo, 1jgp, 1jgq, 1gix - TtRPS2 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+tRNA Phe+mRNA +16S RRNA
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[[1jgo]], [[1jgp]], [[1jgq]], [[1gix]] - TtRPS2 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+tRNA Phe+mRNA +16S RRNA
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3e1a, 3e1c - EcRPS2 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA
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[[3e1a]], [[3e1c]] - EcRPS2 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA
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1i95 - TtRPS2 in 30S ribosomal subunit+16S RRNA+edeine
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[[1i95]] - TtRPS2 in 30S ribosomal subunit+16S RRNA+edeine
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1i97 - TtRPS2 in 30S ribosomal subunit+16S RRNA+tetracycline
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[[1i97]] - TtRPS2 in 30S ribosomal subunit+16S RRNA+tetracycline
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1hnw - TtRPS2 in 30S ribosomal subunit+16S RRNA+mRNA fragment+tetracycline
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[[1hnw]] - TtRPS2 in 30S ribosomal subunit+16S RRNA+mRNA fragment+tetracycline
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1hnx - TtRPS2 in 30S ribosomal subunit+16S RRNA+mRNA fragment+pactamycin
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[[1hnx]] - TtRPS2 in 30S ribosomal subunit+16S RRNA+mRNA fragment+pactamycin
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1hnz - TtRPS2 in 30S ribosomal subunit+16S RRNA+mRNA fragment+hygromycin B
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[[1hnz]] - TtRPS2 in 30S ribosomal subunit+16S RRNA+mRNA fragment+hygromycin B
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1fjg - TtRPS2 in 30S ribosomal subunit+16S RRNA+mRNA fragment+streptomycin
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[[1fjg]] - TtRPS2 in 30S ribosomal subunit+16S RRNA+mRNA fragment+streptomycin
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2qbb, 2qb9 - EcRPS2 in 30S ribosomal subunit+16S RRNA+kasugamyin
+
[[2qbb]], [[2qb9]] - EcRPS2 in 30S ribosomal subunit+16S RRNA+kasugamyin
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2hhh - TtRPS2 in 30S ribosomal subunit+16S RRNA+kasugamyin
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[[2hhh]] - TtRPS2 in 30S ribosomal subunit+16S RRNA+kasugamyin
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2f4v - TtRPS2 in 30S ribosomal subunit+16S RRNA+designed antibiotic
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[[2f4v]] - TtRPS2 in 30S ribosomal subunit+16S RRNA+designed antibiotic
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1vs5, 1vs7 - EcRPS2 in 30S ribosomal subunit+16S RRNA+gentamicin
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[[1vs5]], [[1vs7]] - EcRPS2 in 30S ribosomal subunit+16S RRNA+gentamicin
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2qan, 2qal - EcRPS2 in 30S ribosomal subunit+16S RRNA+neomycin
+
[[2qan]], [[2qal]] - EcRPS2 in 30S ribosomal subunit+16S RRNA+neomycin
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2qou, 2qow - EcRPS2 in 30S ribosomal subunit+16S RRNA+spectinomycin
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[[2qou]], [[2qow]] - EcRPS2 in 30S ribosomal subunit+16S RRNA+spectinomycin
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2qoy, 2qp0 - EcRPS2 in 30S ribosomal subunit+16S RRNA+spectinomycin+neomycin
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[[2qoy]], [[2qp0]] - EcRPS2 in 30S ribosomal subunit+16S RRNA+spectinomycin+neomycin
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2z4k, 2z4m - EcRPS2 in 30S ribosomal subunit+16S RRNA+paromomycin
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[[2z4k]], [[2z4m]] - EcRPS2 in 30S ribosomal subunit+16S RRNA+paromomycin
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2j00, 2j02 - TtRPS2 in 30S ribosomal subunit+16S RRNA+paromomycin+P-site tRNA fMet+E-site tRNA Phe+mRNA
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[[2j00]], [[2j02]] - TtRPS2 in 30S ribosomal subunit+16S RRNA+paromomycin+P-site tRNA fMet+E-site tRNA Phe+mRNA
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3knj, 3knh - TtRPS2 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA+viomycin
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[[3knj]], [[3knh]] - TtRPS2 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA+viomycin
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3knl, 3knm, 3knn, 3kno - TtRPS2 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA+capreomycin
+
[[3knl]], [[3knm]], [[3knn]], [[3kno]] - TtRPS2 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA+capreomycin
Line 119: Line 119:
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2qbd, 2qbf - EcRPS2 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor
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[[2qbd]], [[2qbf]] - EcRPS2 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor
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2qbh, 2qbj - EcRPS2 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor+gentamicin
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[[2qbh]], [[2qbj]] - EcRPS2 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor+gentamicin
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2v46, 2v48 - TtRPS2 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor+P-site tRNA Phe+mRNA+tRNA fMet
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[[2v46]], [[2v48]] - TtRPS2 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor+P-site tRNA Phe+mRNA+tRNA fMet
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2wri, 2wrk - TtRPS2 in 30S ribosomal subunit+THX+P-site tRNA+mRNA +16S RRNA+elongation factor G
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[[2wri]], [[2wrk]] - TtRPS2 in 30S ribosomal subunit+THX+P-site tRNA+mRNA +16S RRNA+elongation factor G
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2wrn, 2wrq - TtRPS2 in 30S ribosomal subunit+THX+A-site tRNA+mRNA +16S RRNA+elongation factor TU-4
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[[2wrn]], [[2wrq]] - TtRPS2 in 30S ribosomal subunit+THX+A-site tRNA+mRNA +16S RRNA+elongation factor TU-4
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3fic - TtRPS2 in 30S ribosomal subunit+THX+A-site tRNA+P-site tRNA+E-site tRNA+mRNA codon+16S RRNA+elongation factor TU-A
+
[[3fic]] - TtRPS2 in 30S ribosomal subunit+THX+A-site tRNA+P-site tRNA+E-site tRNA+mRNA codon+16S RRNA+elongation factor TU-A
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3fih - EcRPS2 in 30S ribosomal subunit+A-site tRNA Phe+P-site tRNA+mRNA +16S RRNA+elongation factor TU
+
[[3fih]] - EcRPS2 in 30S ribosomal subunit+A-site tRNA Phe+P-site tRNA+mRNA +16S RRNA+elongation factor TU
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3huw, 3huy - TtRPS2 in 30S ribosomal subunit+THX+tRNA-Met+mRNA +16S RRNA+elongation factor P
+
[[3huw]], [[3huy]] - TtRPS2 in 30S ribosomal subunit+THX+tRNA-Met+mRNA +16S RRNA+elongation factor P
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1s1h - RPS2 in 40S ribosomal subunit+18S RRNA+elongation factor 2 – Cryo-EM – yeast
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[[1s1h]] - RPS2 in 40S ribosomal subunit+18S RRNA+elongation factor 2 – Cryo-EM – yeast
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1i96 - TtRPS2 in 30S ribosomal subunit+THX+IF3+16S RRNA
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[[1i96]] - TtRPS2 in 30S ribosomal subunit+THX+IF3+16S RRNA
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1hr0 - TtRPS2 in 30S ribosomal subunit+THX+IF+16S RRNA
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[[1hr0]] - TtRPS2 in 30S ribosomal subunit+THX+IF+16S RRNA
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3jyv - TlRPS2 in 40S ribosomal subunit+RACK1+S19E+P-site tRNA – Thermomyces lanuginosus
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[[3jyv]] - TlRPS2 in 40S ribosomal subunit+RACK1+S19E+P-site tRNA – Thermomyces lanuginosus
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3kiq, 3kis, 3kiu, 3kix - TtRPS2 in 30S ribosomal subunit+toxin RelE+16S RRNA
+
[[3kiq]], [[3kis]], [[3kiu]], [[3kix]] - TtRPS2 in 30S ribosomal subunit+toxin RelE+16S RRNA
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1voq, 1vos , 1vov, 1vox, 1voz - EcRPS2 in 30S ribosomal subunit+protein Y+16S RRNA
+
[[1voq]], [[1vos]] , [[1vov]], [[1vox]], [[1voz]] - EcRPS2 in 30S ribosomal subunit+protein Y+16S RRNA
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1x18 – TtRPS2+TtRPS7+TtRPS11+TtRPS18+GTP-binding protein ERA+RNA fragments
+
[[1x18]] – TtRPS2+TtRPS7+TtRPS11+TtRPS18+GTP-binding protein ERA+RNA fragments

Revision as of 10:16, 20 September 2010

Image:S2.PNG
Crystal Structure of Ribosomal protein S2 (RPS2), 3kc4

Template:STRUCTURE 3kc4

Ribosomal protein S2 (RPS2) is one of the 22 proteins which belong to the small subunit of the ribosome. Its N-terminal is rich in Arg-Gly repeats and has two RGGF copies which are believed to be associated with nuclear localization and binding to RNA. The images at the left and at the right correspond to one representative RPS2, i.e. the crystal structure of Ribosomal protein S2 from Escherichia coli (3kc4).

3D Structures of Ribosomal protein S2

S2 in small ribosomal subunit

2zm6, 1n36, 1j5e - TtRPS2 in 30S ribosomal subunit+THX+16S RRNA – Thermus thermophilus 2vqe, 2vqf, 2uuc, 2e5l, 2uu9, 2uua, 2uub - TtRPS2 in 30S ribosomal subunit+16S RRNA+RNA fragment 3kc4 - EcRPS2 in 30S ribosomal subunit - Escherichia coli 3i1m, 3i1o, 3df1, 3df3, 2vho, 2vhp, 2avy, 2aw7, 1pnx - EcRPS2 in 30S ribosomal subunit+16S RRNA 1i94, 1fka - TtRPS2 in 30S ribosomal subunit+16S RRNA 1p87 - EcRPS2 in 30S ribosomal subunit+16S RRNA – Cryo-EM 3bbn - RPS2 in 30S ribosomal subunit+16S RRNA – Cryo-EM – spinach


S2 in small + large ribosomal subunit

1ml5 - EcRPS2 in 30S ribosomal subunit+50S ribosomal subunit+THX+chain release factor 2+P-site tRNA+tRNA Phe+mRNA fragment+23S RRNA+5S RRNA+16S RRNA - EM


S2 in small ribosomal subunit+ chain release factor

3mr8, 3ms0 – TtRPS2 in 30S ribosomal subunit+THX+chain release factor 1+P-site tRNA+mRNA+16S RRNA 3d5a, 3d5c - TtRPS2 in 30S ribosomal subunit+THX+chain release factor 1+P-site tRNA+E-site tRNA+mRNA +16S RRNA 2b64 - TtRPS2 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA+chain release factor 1 2b9m - TtRPS2 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA+chain release factor 2 2x9r, 2x9t, 2wh1, 2wh3 - TtRPS2 in 30S ribosomal subunit+THX+chain release factor 2+P-site tRNA+mRNA +16S RRNA 3f1e, 3f1g - TtRPS2 in 30S ribosomal subunit+THX+chain release factor 2+P-site tRNA+E-site tRNA +16S RRNA


S2 in small ribosomal subunit+tRNA+mRNA

2hgi - TtRPS2 in 30S ribosomal subunit+16S RRNA+tRNA Phe+tRNA fMet 2hgp, 2i2p, 2i2u - TtRPS2 in 30S ribosomal subunit+16S RRNA+tRNA Phe+mRNA 2hgr - TtRPS2 in 30S ribosomal subunit+16S RRNA+tRNA Phe+tRNA fMet+mRNA 1yl4 – TtRPS2 in 30S ribosomal subunit+ tRNA Phe+16S RRNA+THRS mRNA operator 1pns - EcRPS2 in 30S ribosomal subunit+ tRNA Phe+16S RRNA+mRNA 1xnq, 1xnr- TtRPS2 in 30S ribosomal subunit+THX+mRNA+tRNA anticodon+16S RRNA


S2 in small ribosomal subunit+A-site tRNA

2uxd, 2uxc - TtRPS2 in 30S ribosomal subunit+THX+A-site mRNA CGGG+tRNA anticodon+16S RRNA 1n32, 1n33 - TtRPS2 in 30S ribosomal subunit+THX+A-site mRNA fragment+tRNA anticodon+16S RRNA 1n34 - TtRPS2 in 30S ribosomal subunit+THX+A-site mRNA fragment +16S RRNA 1xmo, 1xmq - TtRPS2 in 30S ribosomal subunit+THX+A-site mRNA+tRNA anticodon+16S RRNA 2uxb - TtRPS2 in 30S ribosomal subunit+THX+A-site mRNA GGGU+tRNA anticodon+16S RRNA


S2 in small ribosomal subunit+P-site tRNA

3i8g - TtRPS2 in 30S ribosomal subunit+P-site tRNA+mRNA +16S RRNA 3i8h, 3i9b, 3i9d - TtRPS2 in 30S ribosomal subunit+THX+P-site tRNA+mRNA +16S RRNA 1ibk - TtRPS2 in 30S ribosomal subunit+THX+P-site mRNA fragment +16S RRNA 2wwl - EcRPS2 in 30S ribosomal subunit+Poly-Ala chain+P-site tRNA+mRNA +16S RRNA 3i1q - EcRPS2 in 30S ribosomal subunit+P-site tRNA hairpin+mRNA 3i1s, 3i1z, 3i21 - EcRPS2 in 30S ribosomal subunit+P-site tRNA hairpin+mRNA +16S RNA 2om7 – TtRPS2+TtRPS12+TtRPL1+ P-site tRNA+16S RRNA fragment+23S RRNA fragment


S2 in small ribosomal subunit+A-site tRNA+P-site tRNA

1ibl, 1ibm - TtRPS2 in 30S ribosomal subunit+THX+A-site mRNA fragment+P-site mRNA fragment+tRNA anticodon+16S RRNA


S2 in small ribosomal subunit+P-site tRNA+E-site tRNA

2ow8 - TtRPS2 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA+mRNA +16S RRNA 2b9o - TtRPS2 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA 2qnh - TtRPS2 in 30S ribosomal subunit+THX+P-site tRNA+E-site tRNA+mRNA +16S RRNA 2wdg, 2wdh, 2wdk, 2wdm - TtRPS2 in 30S ribosomal subunit+THX+P-site tRNA+E-site tRNA+mRNA +16S RRNA+tRNA Phe


S2 in small ribosomal subunit+A-site tRNA+P-site tRNA+E-site tRNA

2gy9, 2gyb - EcRPS2 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA – Cryo-EM 1jgo, 1jgp, 1jgq, 1gix - TtRPS2 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+tRNA Phe+mRNA +16S RRNA 3e1a, 3e1c - EcRPS2 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA


S2 in small ribosomal subunit + antibiotics

1i95 - TtRPS2 in 30S ribosomal subunit+16S RRNA+edeine 1i97 - TtRPS2 in 30S ribosomal subunit+16S RRNA+tetracycline 1hnw - TtRPS2 in 30S ribosomal subunit+16S RRNA+mRNA fragment+tetracycline 1hnx - TtRPS2 in 30S ribosomal subunit+16S RRNA+mRNA fragment+pactamycin 1hnz - TtRPS2 in 30S ribosomal subunit+16S RRNA+mRNA fragment+hygromycin B 1fjg - TtRPS2 in 30S ribosomal subunit+16S RRNA+mRNA fragment+streptomycin 2qbb, 2qb9 - EcRPS2 in 30S ribosomal subunit+16S RRNA+kasugamyin 2hhh - TtRPS2 in 30S ribosomal subunit+16S RRNA+kasugamyin 2f4v - TtRPS2 in 30S ribosomal subunit+16S RRNA+designed antibiotic 1vs5, 1vs7 - EcRPS2 in 30S ribosomal subunit+16S RRNA+gentamicin 2qan, 2qal - EcRPS2 in 30S ribosomal subunit+16S RRNA+neomycin 2qou, 2qow - EcRPS2 in 30S ribosomal subunit+16S RRNA+spectinomycin 2qoy, 2qp0 - EcRPS2 in 30S ribosomal subunit+16S RRNA+spectinomycin+neomycin 2z4k, 2z4m - EcRPS2 in 30S ribosomal subunit+16S RRNA+paromomycin 2j00, 2j02 - TtRPS2 in 30S ribosomal subunit+16S RRNA+paromomycin+P-site tRNA fMet+E-site tRNA Phe+mRNA 3knj, 3knh - TtRPS2 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA+viomycin 3knl, 3knm, 3knn, 3kno - TtRPS2 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA+capreomycin


S2 in small ribosomal subunit + ribosome recycling factor

2qbd, 2qbf - EcRPS2 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor 2qbh, 2qbj - EcRPS2 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor+gentamicin 2v46, 2v48 - TtRPS2 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor+P-site tRNA Phe+mRNA+tRNA fMet


S2 in small ribosomal subunit + elongation factor

2wri, 2wrk - TtRPS2 in 30S ribosomal subunit+THX+P-site tRNA+mRNA +16S RRNA+elongation factor G 2wrn, 2wrq - TtRPS2 in 30S ribosomal subunit+THX+A-site tRNA+mRNA +16S RRNA+elongation factor TU-4 3fic - TtRPS2 in 30S ribosomal subunit+THX+A-site tRNA+P-site tRNA+E-site tRNA+mRNA codon+16S RRNA+elongation factor TU-A 3fih - EcRPS2 in 30S ribosomal subunit+A-site tRNA Phe+P-site tRNA+mRNA +16S RRNA+elongation factor TU 3huw, 3huy - TtRPS2 in 30S ribosomal subunit+THX+tRNA-Met+mRNA +16S RRNA+elongation factor P 1s1h - RPS2 in 40S ribosomal subunit+18S RRNA+elongation factor 2 – Cryo-EM – yeast


S2 in small ribosomal subunit + translation initiation factor

1i96 - TtRPS2 in 30S ribosomal subunit+THX+IF3+16S RRNA 1hr0 - TtRPS2 in 30S ribosomal subunit+THX+IF+16S RRNA


S2 in small ribosomal subunit + various proteins

3jyv - TlRPS2 in 40S ribosomal subunit+RACK1+S19E+P-site tRNA – Thermomyces lanuginosus 3kiq, 3kis, 3kiu, 3kix - TtRPS2 in 30S ribosomal subunit+toxin RelE+16S RRNA 1voq, 1vos , 1vov, 1vox, 1voz - EcRPS2 in 30S ribosomal subunit+protein Y+16S RRNA 1x18 – TtRPS2+TtRPS7+TtRPS11+TtRPS18+GTP-binding protein ERA+RNA fragments

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Michal Harel, Alexander Berchansky, Wayne Decatur, Joel L. Sussman

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