Tositumomab
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(New page: ===Pharmacokinetics=== {| class="wikitable" border="1" width="52%" style="text-align:center" |- ! colspan="12" align="center"| Anti-CD20 Monoclonal Antibody [[Pharmaceutical_Drugs#Pharmac...)
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Revision as of 06:36, 6 December 2010
Pharmacokinetics
| Anti-CD20 Monoclonal Antibody Pharmacokinetics | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Parameter | Tositumomab | Ofatumumab | Rituximab | Ibritumomab | |||||||
| Tmax (hr) | Tositumomab | Ofatumumab | Rituximab | Ibritumomab | |||||||
| Cmax (ng/ml) | Tositumomab | Ofatumumab | Rituximab | Ibritumomab | |||||||
| Bioavailability (%) | Tositumomab | Ofatumumab | Rituximab | Ibritumomab | |||||||
| Protein Binding (%) | Tositumomab | Ofatumumab | Rituximab | Ibritumomab | |||||||
| T1/2 (hr) | Tositumomab | Ofatumumab | Rituximab | Ibritumomab | |||||||
| AUC (ng/ml/hr) | Tositumomab | Ofatumumab | Rituximab | Ibritumomab | |||||||
| Clearance (L/h) | Tositumomab | Ofatumumab | Rituximab | Ibritumomab | |||||||
| Tositumomab | Ofatumumab | Rituximab | Ibritumomab | ||||||||
| Tositumomab | Ofatumumab | Rituximab | Ibritumomab | ||||||||
