Tositumomab

(Difference between revisions)

Revision as of 06:38, 6 December 2010

Anti-CD20 Monoclonal Antibody Pharmacokinetics
Parameter	Tositumomab	Ofatumumab	Rituximab	Ibritumomab
T_max (hr)	Tositumomab	Ofatumumab	Rituximab	Ibritumomab
C_max (ng/ml)	Tositumomab	Ofatumumab	Rituximab	Ibritumomab
Bioavailability (%)	Tositumomab	Ofatumumab	Rituximab	Ibritumomab
Protein Binding (%)	Tositumomab	Ofatumumab	Rituximab	Ibritumomab
T_1/2 (hr)	Tositumomab	Ofatumumab	Rituximab	Ibritumomab
AUC (ng/ml/hr)	Tositumomab	Ofatumumab	Rituximab	Ibritumomab
Clearance (L/h)	Tositumomab	Ofatumumab	Rituximab	Ibritumomab
IC₅₀ (nM)	Tositumomab	Ofatumumab	Rituximab	Ibritumomab
Dosage (mg)	Tositumomab	Ofatumumab	Rituximab	Ibritumomab
Metabolism	Tositumomab	Ofatumumab	Rituximab	Ibritumomab

@@ Line 52: / Line 52: @@
 ! Ibritumomab
 |-
+! [[Pharmaceutical_Drugs#Inhibitory_Concentration_.28IC50.29|IC<sub>50</sub>]] (nM)
 ! Tositumomab
 ! Ofatumumab
@@ Line 57: / Line 58: @@
 ! Ibritumomab
 |-
+! Dosage (mg)
 ! Tositumomab
 ! Ofatumumab
 ! Rituximab
 ! Ibritumomab
+|-
+! Metabolism
+! Tositumomab
+! Ofatumumab
+! Rituximab
+! Ibritumomab
+|}
 |}