3frf
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
| - | + | [[3frf]] is a 1 chain structure of [[Dihydrofolate reductase]] with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FRF OCA]. | |
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| + | ==See Also== | ||
| + | *[[Dihydrofolate reductase]] | ||
==Reference== | ==Reference== | ||
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[[Category: One-carbon metabolism]] | [[Category: One-carbon metabolism]] | ||
[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 13 14:11:01 2010'' | ||
Revision as of 20:26, 26 December 2010
Contents |
S. aureus DHFR complexed with NADPH and iclaprim
Template:ABSTRACT PUBMED 19211577
About this Structure
3frf is a 1 chain structure of Dihydrofolate reductase with sequence from Staphylococcus aureus. Full crystallographic information is available from OCA.
See Also
Reference
- Oefner C, Bandera M, Haldimann A, Laue H, Schulz H, Mukhija S, Parisi S, Weiss L, Lociuro S, Dale GE. Increased hydrophobic interactions of iclaprim with Staphylococcus aureus dihydrofolate reductase are responsible for the increase in affinity and antibacterial activity. J Antimicrob Chemother. 2009 Apr;63(4):687-98. Epub 2009 Feb 11. PMID:19211577 doi:10.1093/jac/dkp024
