1s3u
From Proteopedia
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| - | {{Seed}} | ||
[[Image:1s3u.png|left|200px]] | [[Image:1s3u.png|left|200px]] | ||
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{{ABSTRACT_PUBMED_15039552}} | {{ABSTRACT_PUBMED_15039552}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Anemia, megaloblastic, due to DHFR deficiency (1) OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=126060 126060]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[1s3u]] is a 1 chain structure of [[Dihydrofolate reductase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S3U OCA]. | |
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| + | ==See Also== | ||
| + | *[[Dihydrofolate reductase]] | ||
==Reference== | ==Reference== | ||
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[[Category: Dihydrofolate reductase]] | [[Category: Dihydrofolate reductase]] | ||
[[Category: Inhibitor complex]] | [[Category: Inhibitor complex]] | ||
| - | + | [[Category: Oxidoreductase]] | |
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Revision as of 21:04, 26 December 2010
Contents |
Structure Determination of Tetrahydroquinazoline Antifolates in Complex with Human and Pneumocystis carinii Dihydrofolate Reductase: Correlations of Enzyme Selectivity and Stereochemistry
Template:ABSTRACT PUBMED 15039552
About this Structure
1s3u is a 1 chain structure of Dihydrofolate reductase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Cody V, Luft JR, Pangborn W, Gangjee A, Queener SF. Structure determination of tetrahydroquinazoline antifolates in complex with human and Pneumocystis carinii dihydrofolate reductase: correlations between enzyme selectivity and stereochemistry. Acta Crystallogr D Biol Crystallogr. 2004 Apr;60(Pt 4):646-55. Epub 2004, Mar 23. PMID:15039552 doi:http://dx.doi.org/10.1107/S0907444904002094
