2anq
From Proteopedia
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[[Image:2anq.png|left|200px]] | [[Image:2anq.png|left|200px]] | ||
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==About this Structure== | ==About this Structure== | ||
- | + | [[2anq]] is a 1 chain structure of [[Dihydrofolate reductase]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ANQ OCA]. | |
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+ | ==See Also== | ||
+ | *[[Dihydrofolate reductase]] | ||
==Reference== | ==Reference== | ||
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[[Category: Summerfield, R L.]] | [[Category: Summerfield, R L.]] | ||
[[Category: Dhfr]] | [[Category: Dhfr]] | ||
+ | [[Category: Oxidoreductase]] | ||
[[Category: Protein inhibitor complex]] | [[Category: Protein inhibitor complex]] | ||
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- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 18:25:12 2009'' |
Revision as of 00:37, 27 December 2010
Contents |
Crystal Structure of E.coli DHFR in complex with NADPH and the inhibitor compound 10a.
Template:ABSTRACT PUBMED 17125251
About this Structure
2anq is a 1 chain structure of Dihydrofolate reductase with sequence from Escherichia coli. Full crystallographic information is available from OCA.
See Also
Reference
- Summerfield RL, Daigle DM, Mayer S, Mallik D, Hughes DW, Jackson SG, Sulek M, Organ MG, Brown ED, Junop MS. A 2.13 A structure of E. coli dihydrofolate reductase bound to a novel competitive inhibitor reveals a new binding surface involving the M20 loop region. J Med Chem. 2006 Nov 30;49(24):6977-86. PMID:17125251 doi:10.1021/jm060570v