3fra

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Revision as of 01:39, 27 December 2010

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Template:STRUCTURE 3fra

Contents 1 Staphylococcus aureus F98Y DHFR complexed with iclaprim 2 About this Structure 3 See Also 4 Reference

Staphylococcus aureus F98Y DHFR complexed with iclaprim

Template:ABSTRACT PUBMED 19211577

About this Structure

3fra is a 1 chain structure of Dihydrofolate reductase with sequence from Staphylococcus aureus. Full crystallographic information is available from OCA.

See Also

• Dihydrofolate reductase

Reference

• Oefner C, Bandera M, Haldimann A, Laue H, Schulz H, Mukhija S, Parisi S, Weiss L, Lociuro S, Dale GE. Increased hydrophobic interactions of iclaprim with Staphylococcus aureus dihydrofolate reductase are responsible for the increase in affinity and antibacterial activity. J Antimicrob Chemother. 2009 Apr;63(4):687-98. Epub 2009 Feb 11. PMID:19211577 doi:10.1093/jac/dkp024