1aoe

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	==Reference==		==Reference==
-	<ref group="xtra">PMID:9374515</ref><references group="xtra"/>	+	<ref group="xtra">PMID:009374515</ref><ref group="xtra">PMID:012704428</ref><references group="xtra"/>
	[[Category: Candida albicans]]		[[Category: Candida albicans]]
	[[Category: Dihydrofolate reductase]]		[[Category: Dihydrofolate reductase]]

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Revision as of 12:47, 28 April 2011

Template:STRUCTURE 1aoe

Contents 1 CANDIDA ALBICANS DIHYDROFOLATE REDUCTASE COMPLEXED WITH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (NADPH) AND 1,3-DIAMINO-7-(1-ETHYEPROPYE)-7H-PYRRALO-[3,2-F]QUINAZOLINE (GW345) 2 About this Structure 3 See Also 4 Reference

CANDIDA ALBICANS DIHYDROFOLATE REDUCTASE COMPLEXED WITH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (NADPH) AND 1,3-DIAMINO-7-(1-ETHYEPROPYE)-7H-PYRRALO-[3,2-F]QUINAZOLINE (GW345)

Template:ABSTRACT PUBMED 9374515

About this Structure

1aoe is a 2 chain structure of Dihydrofolate reductase with sequence from Candida albicans. Full crystallographic information is available from OCA.

See Also

• Dihydrofolate reductase

Reference

• Whitlow M, Howard AJ, Stewart D, Hardman KD, Kuyper LF, Baccanari DP, Fling ME, Tansik RL. X-ray crystallographic studies of Candida albicans dihydrofolate reductase. High resolution structures of the holoenzyme and an inhibited ternary complex. J Biol Chem. 1997 Nov 28;272(48):30289-98. PMID:9374515
• Yuvaniyama J, Chitnumsub P, Kamchonwongpaisan S, Vanichtanankul J, Sirawaraporn W, Taylor P, Walkinshaw MD, Yuthavong Y. Insights into antifolate resistance from malarial DHFR-TS structures. Nat Struct Biol. 2003 May;10(5):357-65. PMID:12704428 doi:10.1038/nsb921