Flagellar filament of bacteria
From Proteopedia
(Difference between revisions)
(→R vs. L forms) |
(→R vs. L forms) |
||
| Line 2: | Line 2: | ||
==R vs. L forms== | ==R vs. L forms== | ||
| - | < | + | Quoted from <ref name="3a5x" />" |
| + | <blockquote> | ||
| + | "The bacterial flagellar filament is a helical propeller rotated by the flagellar motor for bacterial locomotion. The filament is a supercoiled assembly of a single protein, flagellin, and is formed by 11 protofilaments. For bacterial taxis, the reversal of motor rotation switches the supercoil between left- and right-handed, both of which arise from combinations of two distinct conformations and packing interactions of the L-type and R-type protofilaments." | ||
| + | </blockquote> | ||
| - | The structure of a straight R form of the flagellar filament was | + | The structure of a straight R form of the flagellar filament was reported in 2003<ref name="1ucu">PMID: 12904785</ref>, by fitting a crystallographic model of the monomer<ref name="1io1">PMID: 11268201</ref> into an electron cryomicroscopic density map with resolution approaching 4 Å. The resulting full-length R form monomer, [[1ucu]], included terminal alpha helices that were absent in the crystallographic model. |
| - | + | ||
| - | + | ||
| + | The structure of a straight L form of the flagellar filament was reported in 2010<ref name="3a5x">Maki-Yonekura, S., K. Yonekura, & K. Namba, 'Conformational change of flagellin for polymorphic supercoiling of the flagellar filament', Nat. Struct. Mol. Biol. 17, 417–422 (2010). [http://dx.doi.org/10.1038/nsmb.1774 doi:10.1038/nsmb.1774]</ref>. | ||
| + | <Structure size='450' frame='true' align='right' caption='Insert caption here' scene='' /> | ||
*<scene name='Flagellar_filament_of_bacteria/Yale_morph_r_to_l/1'>R to L Morph (all residues aligned)</scene><ref>Chemically possible morph generated by the [http://molmovdb.org Yale Morph Server (molmovdb.org)], [[1ucu]] to [[3a5x]].</ref> | *<scene name='Flagellar_filament_of_bacteria/Yale_morph_r_to_l/1'>R to L Morph (all residues aligned)</scene><ref>Chemically possible morph generated by the [http://molmovdb.org Yale Morph Server (molmovdb.org)], [[1ucu]] to [[3a5x]].</ref> | ||
Revision as of 12:56, 14 May 2011
R vs. L forms
Quoted from [1]"
"The bacterial flagellar filament is a helical propeller rotated by the flagellar motor for bacterial locomotion. The filament is a supercoiled assembly of a single protein, flagellin, and is formed by 11 protofilaments. For bacterial taxis, the reversal of motor rotation switches the supercoil between left- and right-handed, both of which arise from combinations of two distinct conformations and packing interactions of the L-type and R-type protofilaments."
The structure of a straight R form of the flagellar filament was reported in 2003[2], by fitting a crystallographic model of the monomer[3] into an electron cryomicroscopic density map with resolution approaching 4 Å. The resulting full-length R form monomer, 1ucu, included terminal alpha helices that were absent in the crystallographic model.
The structure of a straight L form of the flagellar filament was reported in 2010[1].
|
Notes
- ↑ 1.0 1.1 Maki-Yonekura, S., K. Yonekura, & K. Namba, 'Conformational change of flagellin for polymorphic supercoiling of the flagellar filament', Nat. Struct. Mol. Biol. 17, 417–422 (2010). doi:10.1038/nsmb.1774
- ↑ Yonekura K, Maki-Yonekura S, Namba K. Complete atomic model of the bacterial flagellar filament by electron cryomicroscopy. Nature. 2003 Aug 7;424(6949):643-50. PMID:12904785 doi:http://dx.doi.org/10.1038/nature01830
- ↑ Samatey FA, Imada K, Nagashima S, Vonderviszt F, Kumasaka T, Yamamoto M, Namba K. Structure of the bacterial flagellar protofilament and implications for a switch for supercoiling. Nature. 2001 Mar 15;410(6826):331-7. PMID:11268201 doi:10.1038/35066504
- ↑ Chemically possible morph generated by the Yale Morph Server (molmovdb.org), 1ucu to 3a5x.
