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1acj
From Proteopedia
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Revision as of 09:17, 3 June 2012
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| 1acj, resolution 2.80Å () | |||||||||
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| Ligands: | |||||||||
| Activity: | Acetylcholinesterase, with EC number 3.1.1.7 | ||||||||
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| Resources: | FirstGlance, OCA, RCSB, PDBsum | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
Contents |
QUATERNARY LIGAND BINDING TO AROMATIC RESIDUES IN THE ACTIVE-SITE GORGE OF ACETYLCHOLINESTERASE
Template:ABSTRACT PUBMED 8415649
About this Structure
1acj is a 1 chain structure of Acetylcholinesterase with sequence from Torpedo californica. The June 2004 RCSB PDB Molecule of the Month feature on Acetylcholinesterase by David S. Goodsell is 10.2210/rcsb_pdb/mom_2004_6. Full crystallographic information is available from OCA.
See Also
- AChE bivalent inhibitors
- AChE inhibitors and substrates
- AChE inhibitors and substrates (Part II)
- Acetylcholinesterase
- Alzheimer's Disease
- Demo 1acj
- Quiz Template
- Sandobx 1997
- UMass Chem 423 Student Projects 2011-1
- User:Mary Ball/Glucagon
- User:Mary Ball/Leptin
- User:Mary Ball/Scenes
Reference
- Harel M, Schalk I, Ehret-Sabatier L, Bouet F, Goeldner M, Hirth C, Axelsen PH, Silman I, Sussman JL. Quaternary ligand binding to aromatic residues in the active-site gorge of acetylcholinesterase. Proc Natl Acad Sci U S A. 1993 Oct 1;90(19):9031-5. PMID:8415649
- Pomponi M, Marta M, Colella A, Sacchi S, Patamia M, Gatta F, Capone F, Oliverio A, Pavone F. Studies on a new series of THA analogues: effects of the aromatic residues that line the gorge of AChE. FEBS Lett. 1997 Jun 9;409(2):155-60. PMID:9202137
