Staphylococcal nuclease
From Proteopedia
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Revision as of 18:29, 5 June 2012
Micrococcal nuclease, or Staphylococcal nuclease, is a monomeric Ca++ dependent enzyme of 149 amino acids that cleaves either DNA or RNA substrates. It is used for relatively non-specific cleavage of nucleic acids in molecular biology, and has been an important model system for the study of protein folding.
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Structure
The first structure was solved in 1969 in the Cotton lab at MIT and published in 1971[1].
Proteopedia Page Contributors and Editors (what is this?)
Michal Harel, Alexander Berchansky, Joel L. Sussman, Jaime Prilusky, Jane S. Richardson
