3inm
From Proteopedia
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[[Image:3inm.png|left|200px]] | [[Image:3inm.png|left|200px]] | ||
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{{STRUCTURE_3inm| PDB=3inm | SCENE= }} | {{STRUCTURE_3inm| PDB=3inm | SCENE= }} | ||
===Crystal structure of human cytosolic NADP(+)-dependent isocitrate dehydrogenase R132H mutant in complex with NADPH, ALPHA-KETOGLUTARATE and CALCIUM(2+)=== | ===Crystal structure of human cytosolic NADP(+)-dependent isocitrate dehydrogenase R132H mutant in complex with NADPH, ALPHA-KETOGLUTARATE and CALCIUM(2+)=== | ||
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{{ABSTRACT_PUBMED_19935646}} | {{ABSTRACT_PUBMED_19935646}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[3inm]] is a 3 chain structure of [[Isocitrate dehydrogenase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3INM OCA]. | + | [[3inm]] is a 3 chain structure of [[Ferguson sandbox 1]] and [[Isocitrate dehydrogenase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3INM OCA]. |
==See Also== | ==See Also== | ||
| - | *[[Isocitrate dehydrogenase]] | + | *[[Ferguson sandbox 1|Ferguson sandbox 1]] |
| + | *[[Isocitrate dehydrogenase|Isocitrate dehydrogenase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019935646</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Bhyravbhatla, B.]] | [[Category: Bhyravbhatla, B.]] | ||
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[[Category: Fontano, E.]] | [[Category: Fontano, E.]] | ||
[[Category: Suto, R K.]] | [[Category: Suto, R K.]] | ||
| - | [[Category: Calcium]] | ||
| - | [[Category: Cytoplasm]] | ||
[[Category: Glyoxylate bypass]] | [[Category: Glyoxylate bypass]] | ||
[[Category: Ketoglutarate]] | [[Category: Ketoglutarate]] | ||
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[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
[[Category: Peroxisome]] | [[Category: Peroxisome]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Quaternary complex]] | [[Category: Quaternary complex]] | ||
[[Category: Rossmann fold]] | [[Category: Rossmann fold]] | ||
[[Category: Tricarboxylic acid cycle]] | [[Category: Tricarboxylic acid cycle]] | ||
Revision as of 09:43, 25 July 2012
Contents |
Crystal structure of human cytosolic NADP(+)-dependent isocitrate dehydrogenase R132H mutant in complex with NADPH, ALPHA-KETOGLUTARATE and CALCIUM(2+)
Template:ABSTRACT PUBMED 19935646
About this Structure
3inm is a 3 chain structure of Ferguson sandbox 1 and Isocitrate dehydrogenase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Dang L, White DW, Gross S, Bennett BD, Bittinger MA, Driggers EM, Fantin VR, Jang HG, Jin S, Keenan MC, Marks KM, Prins RM, Ward PS, Yen KE, Liau LM, Rabinowitz JD, Cantley LC, Thompson CB, Vander Heiden MG, Su SM. Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. Nature. 2009 Dec 10;462(7274):739-44. Epub . PMID:19935646 doi:10.1038/nature08617
