1ook
From Proteopedia
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===Crystal Structure of the Complex of Platelet Receptor GPIb-alpha and Human alpha-Thrombin=== | ===Crystal Structure of the Complex of Platelet Receptor GPIb-alpha and Human alpha-Thrombin=== | ||
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- | ==Disease== | ||
- | Known disease associated with this structure: Bernard-Soulier syndrome, benign autosomal dominant OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606672 606672]], Bernard-Soulier syndrome, type A OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606672 606672]], von Willebrand disease, platelet-type OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606672 606672]], Nonarteritic anterior ischemic optic neuropathy, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606672 606672]] | ||
==About this Structure== | ==About this Structure== | ||
- | + | [[1ook]] is a 4 chain structure of [[Platelet-receptor glycoprotein Ib alpha]] and [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OOK OCA]. | |
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+ | ==See Also== | ||
+ | *[[Platelet-receptor glycoprotein Ib alpha|Platelet-receptor glycoprotein Ib alpha]] | ||
+ | *[[Thrombin|Thrombin]] | ||
==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:012855810</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Thrombin]] | [[Category: Thrombin]] | ||
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[[Category: Ruggeri, Z M.]] | [[Category: Ruggeri, Z M.]] | ||
[[Category: Varughese, K I.]] | [[Category: Varughese, K I.]] | ||
+ | [[Category: Hydrolase]] | ||
[[Category: Leucine rich repeat]] | [[Category: Leucine rich repeat]] | ||
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- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 16:15:38 2009'' |
Revision as of 17:21, 25 July 2012
Contents |
Crystal Structure of the Complex of Platelet Receptor GPIb-alpha and Human alpha-Thrombin
Template:ABSTRACT PUBMED 12855810
About this Structure
1ook is a 4 chain structure of Platelet-receptor glycoprotein Ib alpha and Thrombin with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Celikel R, McClintock RA, Roberts JR, Mendolicchio GL, Ware J, Varughese KI, Ruggeri ZM. Modulation of alpha-thrombin function by distinct interactions with platelet glycoprotein Ibalpha. Science. 2003 Jul 11;301(5630):218-21. PMID:12855810 doi:http://dx.doi.org/10.1126/science.1084183