1ook

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{{Seed}}
 
[[Image:1ook.png|left|200px]]
[[Image:1ook.png|left|200px]]
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{{STRUCTURE_1ook| PDB=1ook | SCENE= }}
{{STRUCTURE_1ook| PDB=1ook | SCENE= }}
===Crystal Structure of the Complex of Platelet Receptor GPIb-alpha and Human alpha-Thrombin===
===Crystal Structure of the Complex of Platelet Receptor GPIb-alpha and Human alpha-Thrombin===
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{{ABSTRACT_PUBMED_12855810}}
{{ABSTRACT_PUBMED_12855810}}
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==Disease==
 
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Known disease associated with this structure: Bernard-Soulier syndrome, benign autosomal dominant OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606672 606672]], Bernard-Soulier syndrome, type A OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606672 606672]], von Willebrand disease, platelet-type OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606672 606672]], Nonarteritic anterior ischemic optic neuropathy, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606672 606672]]
 
==About this Structure==
==About this Structure==
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1OOK is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OOK OCA].
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[[1ook]] is a 4 chain structure of [[Platelet-receptor glycoprotein Ib alpha]] and [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OOK OCA].
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==See Also==
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*[[Platelet-receptor glycoprotein Ib alpha|Platelet-receptor glycoprotein Ib alpha]]
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*[[Thrombin|Thrombin]]
==Reference==
==Reference==
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<ref group="xtra">PMID:12855810</ref><references group="xtra"/>
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<ref group="xtra">PMID:012855810</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Thrombin]]
[[Category: Thrombin]]
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[[Category: Ruggeri, Z M.]]
[[Category: Ruggeri, Z M.]]
[[Category: Varughese, K I.]]
[[Category: Varughese, K I.]]
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[[Category: Hydrolase]]
[[Category: Leucine rich repeat]]
[[Category: Leucine rich repeat]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 16:15:38 2009''
 

Revision as of 17:21, 25 July 2012

Template:STRUCTURE 1ook

Contents

Crystal Structure of the Complex of Platelet Receptor GPIb-alpha and Human alpha-Thrombin

Template:ABSTRACT PUBMED 12855810

About this Structure

1ook is a 4 chain structure of Platelet-receptor glycoprotein Ib alpha and Thrombin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Celikel R, McClintock RA, Roberts JR, Mendolicchio GL, Ware J, Varughese KI, Ruggeri ZM. Modulation of alpha-thrombin function by distinct interactions with platelet glycoprotein Ibalpha. Science. 2003 Jul 11;301(5630):218-21. PMID:12855810 doi:http://dx.doi.org/10.1126/science.1084183

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