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3cse
From Proteopedia
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[[Image:3cse.png|left|200px]] | [[Image:3cse.png|left|200px]] | ||
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{{STRUCTURE_3cse| PDB=3cse | SCENE= }} | {{STRUCTURE_3cse| PDB=3cse | SCENE= }} | ||
===Candida glabrata Dihydrofolate Reductase complexed with NADPH and 2,4-diamino-5-(3-(2,5-dimethoxyphenyl)prop-1-ynyl)-6-ethylpyrimidine (UCP120B)=== | ===Candida glabrata Dihydrofolate Reductase complexed with NADPH and 2,4-diamino-5-(3-(2,5-dimethoxyphenyl)prop-1-ynyl)-6-ethylpyrimidine (UCP120B)=== | ||
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{{ABSTRACT_PUBMED_18804036}} | {{ABSTRACT_PUBMED_18804036}} | ||
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==See Also== | ==See Also== | ||
| - | *[[Dihydrofolate reductase]] | + | *[[Dihydrofolate reductase|Dihydrofolate reductase]] |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018804036</ref><ref group="xtra">PMID:019168759</ref><references group="xtra"/> |
[[Category: Candida glabrata]] | [[Category: Candida glabrata]] | ||
[[Category: Dihydrofolate reductase]] | [[Category: Dihydrofolate reductase]] | ||
Revision as of 20:50, 25 July 2012
Contents |
Candida glabrata Dihydrofolate Reductase complexed with NADPH and 2,4-diamino-5-(3-(2,5-dimethoxyphenyl)prop-1-ynyl)-6-ethylpyrimidine (UCP120B)
Template:ABSTRACT PUBMED 18804036
About this Structure
3cse is a 2 chain structure of Dihydrofolate reductase with sequence from Candida glabrata. Full crystallographic information is available from OCA.
See Also
Reference
- Liu J, Bolstad DB, Smith AE, Priestley ND, Wright DL, Anderson AC. Structure-guided development of efficacious antifungal agents targeting Candida glabrata dihydrofolate reductase. Chem Biol. 2008 Sep 22;15(9):990-6. PMID:18804036 doi:S1074-5521(08)00280-9
- Liu J, Bolstad DB, Bolstad ES, Wright DL, Anderson AC. Towards new antifolates targeting eukaryotic opportunistic infections. Eukaryot Cell. 2009 Apr;8(4):483-6. Epub 2009 Jan 23. PMID:19168759 doi:10.1128/EC.00298-08
