1qk9

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[[Image:1qk9.png|left|200px]]
[[Image:1qk9.png|left|200px]]
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{{STRUCTURE_1qk9| PDB=1qk9 | SCENE= }}
{{STRUCTURE_1qk9| PDB=1qk9 | SCENE= }}
===THE SOLUTION STRUCTURE OF THE DOMAIN FROM MECP2 THAT BINDS TO METHYLATED DNA===
===THE SOLUTION STRUCTURE OF THE DOMAIN FROM MECP2 THAT BINDS TO METHYLATED DNA===
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==See Also==
==See Also==
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*[[Methyl CpG Binding Protein 2]]
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*[[Methyl CpG Binding Protein 2|Methyl CpG Binding Protein 2]]
==Reference==
==Reference==
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<ref group="xtra">PMID:10518942</ref><ref group="xtra">PMID:9774669</ref><ref group="xtra">PMID:9620804</ref><ref group="xtra">PMID:8977030</ref><ref group="xtra">PMID:7844833</ref><ref group="xtra">PMID:2004419</ref><ref group="xtra">PMID:2423876</ref><references group="xtra"/>
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<ref group="xtra">PMID:010518942</ref><ref group="xtra">PMID:009774669</ref><ref group="xtra">PMID:009620804</ref><ref group="xtra">PMID:008977030</ref><ref group="xtra">PMID:007844833</ref><ref group="xtra">PMID:002004419</ref><ref group="xtra">PMID:002423876</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Barlow, P N.]]
[[Category: Barlow, P N.]]
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[[Category: Methyl-cpg-binding protein]]
[[Category: Methyl-cpg-binding protein]]
[[Category: Methylated dna]]
[[Category: Methylated dna]]
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[[Category: Nmr]]
 
[[Category: Solution structure]]
[[Category: Solution structure]]

Revision as of 01:04, 26 July 2012

Template:STRUCTURE 1qk9

Contents

THE SOLUTION STRUCTURE OF THE DOMAIN FROM MECP2 THAT BINDS TO METHYLATED DNA

Template:ABSTRACT PUBMED 10518942

About this Structure

1qk9 is a 1 chain structure of Methyl CpG Binding Protein 2 with sequence from Homo sapiens. Full experimental information is available from OCA.

See Also

Reference

  • Wakefield RI, Smith BO, Nan X, Free A, Soteriou A, Uhrin D, Bird AP, Barlow PN. The solution structure of the domain from MeCP2 that binds to methylated DNA. J Mol Biol. 1999 Sep 3;291(5):1055-65. PMID:10518942 doi:10.1006/jmbi.1999.3023
  • Hendrich B, Bird A. Identification and characterization of a family of mammalian methyl-CpG binding proteins. Mol Cell Biol. 1998 Nov;18(11):6538-47. PMID:9774669
  • Nan X, Ng HH, Johnson CA, Laherty CD, Turner BM, Eisenman RN, Bird A. Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex. Nature. 1998 May 28;393(6683):386-9. PMID:9620804 doi:10.1038/30764
  • Bird AP. The relationship of DNA methylation to cancer. Cancer Surv. 1996;28:87-101 PMID:8977030
  • Nilges M. Calculation of protein structures with ambiguous distance restraints. Automated assignment of ambiguous NOE crosspeaks and disulphide connectivities. J Mol Biol. 1995 Feb 3;245(5):645-60. PMID:7844833 doi:http://dx.doi.org/10.1006/jmbi.1994.0053
  • Boyes J, Bird A. DNA methylation inhibits transcription indirectly via a methyl-CpG binding protein. Cell. 1991 Mar 22;64(6):1123-34. PMID:2004419 doi:10.1016/0092-8674(91)90267-3
  • Bird AP. CpG-rich islands and the function of DNA methylation. Nature. 1986 May 15-21;321(6067):209-13. PMID:2423876 doi:http://dx.doi.org/10.1038/321209a0

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