3fq0

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[[Image:3fq0.png|left|200px]]
[[Image:3fq0.png|left|200px]]
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{{STRUCTURE_3fq0| PDB=3fq0 | SCENE= }}
{{STRUCTURE_3fq0| PDB=3fq0 | SCENE= }}
===Staphylococcus aureus dihydrofolate reductase complexed with NADPH and 2,4-diamino-5-(3-(2,5-dimethoxyphenyl)prop-1-ynyl)-6-ethylpyrimidine (UCP120B)===
===Staphylococcus aureus dihydrofolate reductase complexed with NADPH and 2,4-diamino-5-(3-(2,5-dimethoxyphenyl)prop-1-ynyl)-6-ethylpyrimidine (UCP120B)===
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{{ABSTRACT_PUBMED_19249312}}
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==See Also==
==See Also==
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*[[Dihydrofolate reductase]]
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*[[Dihydrofolate reductase|Dihydrofolate reductase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:19249312</ref><references group="xtra"/>
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<ref group="xtra">PMID:019249312</ref><references group="xtra"/>
[[Category: Dihydrofolate reductase]]
[[Category: Dihydrofolate reductase]]
[[Category: Staphylococcus aureus rf122]]
[[Category: Staphylococcus aureus rf122]]

Revision as of 04:51, 26 July 2012

Template:STRUCTURE 3fq0

Contents

Staphylococcus aureus dihydrofolate reductase complexed with NADPH and 2,4-diamino-5-(3-(2,5-dimethoxyphenyl)prop-1-ynyl)-6-ethylpyrimidine (UCP120B)

Template:ABSTRACT PUBMED 19249312

About this Structure

3fq0 is a 1 chain structure of Dihydrofolate reductase with sequence from Staphylococcus aureus rf122. Full crystallographic information is available from OCA.

See Also

Reference

  • Frey KM, Liu J, Lombardo MN, Bolstad DB, Wright DL, Anderson AC. Crystal structures of wild-type and mutant methicillin-resistant Staphylococcus aureus dihydrofolate reductase reveal an alternate conformation of NADPH that may be linked to trimethoprim resistance. J Mol Biol. 2009 Apr 17;387(5):1298-308. Epub 2009 Feb 26. PMID:19249312 doi:10.1016/j.jmb.2009.02.045

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