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1dis
From Proteopedia
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[[Image:1dis.png|left|200px]] | [[Image:1dis.png|left|200px]] | ||
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{{STRUCTURE_1dis| PDB=1dis | SCENE= }} | {{STRUCTURE_1dis| PDB=1dis | SCENE= }} | ||
===DIHYDROFOLATE REDUCTASE (E.C.1.5.1.3) COMPLEX WITH BRODIMOPRIM-4,6-DICARBOXYLATE=== | ===DIHYDROFOLATE REDUCTASE (E.C.1.5.1.3) COMPLEX WITH BRODIMOPRIM-4,6-DICARBOXYLATE=== | ||
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{{ABSTRACT_PUBMED_7547901}} | {{ABSTRACT_PUBMED_7547901}} | ||
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==See Also== | ==See Also== | ||
| - | *[[Dihydrofolate reductase]] | + | *[[Dihydrofolate reductase|Dihydrofolate reductase]] |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:007547901</ref><ref group="xtra">PMID:010026296</ref><ref group="xtra">PMID:010631979</ref><ref group="xtra">PMID:011734033</ref><references group="xtra"/> |
[[Category: Dihydrofolate reductase]] | [[Category: Dihydrofolate reductase]] | ||
[[Category: Lactobacillus casei]] | [[Category: Lactobacillus casei]] | ||
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[[Category: Polshakov, V I.]] | [[Category: Polshakov, V I.]] | ||
[[Category: Sali, D.]] | [[Category: Sali, D.]] | ||
| - | [[Category: Inhibitor | + | [[Category: Inhibitor-enzyme complex]] |
[[Category: Oxido-reductase]] | [[Category: Oxido-reductase]] | ||
Revision as of 15:45, 26 July 2012
Contents |
DIHYDROFOLATE REDUCTASE (E.C.1.5.1.3) COMPLEX WITH BRODIMOPRIM-4,6-DICARBOXYLATE
Template:ABSTRACT PUBMED 7547901
About this Structure
1dis is a 1 chain structure of Dihydrofolate reductase with sequence from Lactobacillus casei. Full experimental information is available from OCA.
See Also
Reference
- Morgan WD, Birdsall B, Polshakov VI, Sali D, Kompis I, Feeney J. Solution structure of a brodimoprim analogue in its complex with Lactobacillus casei dihydrofolate reductase. Biochemistry. 1995 Sep 19;34(37):11690-702. PMID:7547901
- Morgan WD, Birdsall B, Nieto PM, Gargaro AR, Feeney J. 1H/15N HSQC NMR studies of ligand carboxylate group interactions with arginine residues in complexes of brodimoprim analogues and Lactobacillus casei dihydrofolate reductase. Biochemistry. 1999 Feb 16;38(7):2127-34. PMID:10026296 doi:10.1021/bi982359u
- Xie PT, Hurley TD. Methionine-141 directly influences the binding of 4-methylpyrazole in human sigma sigma alcohol dehydrogenase. Protein Sci. 1999 Dec;8(12):2639-44. PMID:10631979
- Sharman GJ, Griffiths-Jones SR, Jourdan M, Searle MS. Effects of amino acid phi,psi propensities and secondary structure interactions in modulating H alpha chemical shifts in peptide and protein beta-sheet. J Am Chem Soc. 2001 Dec 12;123(49):12318-24. PMID:11734033
