3mas

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Revision as of 19:20, 26 July 2012

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Template:STRUCTURE 3mas

Contents 1 Crystal structure of heterodimeric R132H mutant of human cytosolic NADP(+)-dependent isocitrate dehydrogenase in complex with NADP and isocitrate 2 About this Structure 3 See Also 4 Reference

Crystal structure of heterodimeric R132H mutant of human cytosolic NADP(+)-dependent isocitrate dehydrogenase in complex with NADP and isocitrate

Template:ABSTRACT PUBMED 20975740

About this Structure

3mas is a 2 chain structure of Isocitrate dehydrogenase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Isocitrate dehydrogenase

Reference

• Yang B, Zhong C, Peng Y, Lai Z, Ding J. Molecular mechanisms of "off-on switch" of activities of human IDH1 by tumor-associated mutation R132H. Cell Res. 2010 Nov;20(11):1188-200. Epub 2010 Oct 26. PMID:20975740 doi:10.1038/cr.2010.145