1e26

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{{STRUCTURE_1e26| PDB=1e26 | SCENE= }}
{{STRUCTURE_1e26| PDB=1e26 | SCENE= }}
===DESIGN, SYNTHESIS AND X-RAY CRYSTAL STRUCTURE OF A POTENT DUAL INHIBITOR OF THYMIDYLATE SYNTHASE AND DIHYDROFOLATE REDUCTASE AS AN ANTITUMOR AGENT.===
===DESIGN, SYNTHESIS AND X-RAY CRYSTAL STRUCTURE OF A POTENT DUAL INHIBITOR OF THYMIDYLATE SYNTHASE AND DIHYDROFOLATE REDUCTASE AS AN ANTITUMOR AGENT.===
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{{ABSTRACT_PUBMED_10194348}}
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{{ABSTRACT_PUBMED_11052789}}
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==About this Structure==
==About this Structure==
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1E26 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Pneumocystis_carinii Pneumocystis carinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E26 OCA].
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[[1e26]] is a 1 chain structure of [[Dihydrofolate reductase]] with sequence from [http://en.wikipedia.org/wiki/Pneumocystis_carinii Pneumocystis carinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E26 OCA].
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==See Also==
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*[[Dihydrofolate reductase|Dihydrofolate reductase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:11052789</ref><references group="xtra"/>
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<ref group="xtra">PMID:010194348</ref><references group="xtra"/>
[[Category: Dihydrofolate reductase]]
[[Category: Dihydrofolate reductase]]
[[Category: Pneumocystis carinii]]
[[Category: Pneumocystis carinii]]
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[[Category: Yu, J.]]
[[Category: Yu, J.]]
[[Category: Dihydrofolate reductase]]
[[Category: Dihydrofolate reductase]]
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[[Category: Oxidoreductase]]
[[Category: Thymidylate synthase]]
[[Category: Thymidylate synthase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 14:08:56 2009''
 

Revision as of 19:23, 26 July 2012

Image:1e26.png

Template:STRUCTURE 1e26

Contents

DESIGN, SYNTHESIS AND X-RAY CRYSTAL STRUCTURE OF A POTENT DUAL INHIBITOR OF THYMIDYLATE SYNTHASE AND DIHYDROFOLATE REDUCTASE AS AN ANTITUMOR AGENT.

Template:ABSTRACT PUBMED 10194348

About this Structure

1e26 is a 1 chain structure of Dihydrofolate reductase with sequence from Pneumocystis carinii. Full crystallographic information is available from OCA.

See Also

Reference

  • Cody V, Galitsky N, Rak D, Luft JR, Pangborn W, Queener SF. Ligand-induced conformational changes in the crystal structures of Pneumocystis carinii dihydrofolate reductase complexes with folate and NADP+. Biochemistry. 1999 Apr 6;38(14):4303-12. PMID:10194348 doi:10.1021/bi982728m

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