3fl8
From Proteopedia
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===Crystal structure of B. anthracis dihydrofolate reductase (DHFR) with RAB1, a TMP-dihydrophthalazine derivative=== | ===Crystal structure of B. anthracis dihydrofolate reductase (DHFR) with RAB1, a TMP-dihydrophthalazine derivative=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[3fl8]] is a 8 chain structure of [[Dihydrofolate reductase]] with sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FL8 OCA]. | |
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| + | ==See Also== | ||
| + | *[[Dihydrofolate reductase|Dihydrofolate reductase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019364848</ref><references group="xtra"/> |
[[Category: Bacillus anthracis]] | [[Category: Bacillus anthracis]] | ||
[[Category: Dihydrofolate reductase]] | [[Category: Dihydrofolate reductase]] | ||
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[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
[[Category: Pyrimidine]] | [[Category: Pyrimidine]] | ||
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Revision as of 19:46, 26 July 2012
Contents |
Crystal structure of B. anthracis dihydrofolate reductase (DHFR) with RAB1, a TMP-dihydrophthalazine derivative
Template:ABSTRACT PUBMED 19364848
About this Structure
3fl8 is a 8 chain structure of Dihydrofolate reductase with sequence from Bacillus anthracis. Full crystallographic information is available from OCA.
See Also
Reference
- Bourne CR, Bunce RA, Bourne PC, Berlin KD, Barrow EW, Barrow WW. Crystal structure of Bacillus anthracis dihydrofolate reductase with the dihydrophthalazine-based trimethoprim derivative RAB1 provides a structural explanation of potency and selectivity. Antimicrob Agents Chemother. 2009 Jul;53(7):3065-73. Epub 2009 Apr 13. PMID:19364848 doi:10.1128/AAC.01666-08
