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3i8a

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[[Image:3i8a.png|left|200px]]
[[Image:3i8a.png|left|200px]]
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{{STRUCTURE_3i8a| PDB=3i8a | SCENE= }}
{{STRUCTURE_3i8a| PDB=3i8a | SCENE= }}
===Staphylococcus aureus H30N, F98Y Dihydrofolate Reductase complexed with NADPH and 2,4-diamino-5-(3-(2,5-dimethoxyphenyl)prop-1-ynyl)-6-ethylpyrimidine (UCP120B)===
===Staphylococcus aureus H30N, F98Y Dihydrofolate Reductase complexed with NADPH and 2,4-diamino-5-(3-(2,5-dimethoxyphenyl)prop-1-ynyl)-6-ethylpyrimidine (UCP120B)===
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==See Also==
==See Also==
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*[[Dihydrofolate reductase]]
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*[[Dihydrofolate reductase|Dihydrofolate reductase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:20026215</ref><references group="xtra"/>
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<ref group="xtra">PMID:020026215</ref><references group="xtra"/>
[[Category: Dihydrofolate reductase]]
[[Category: Dihydrofolate reductase]]
[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]

Revision as of 07:40, 27 July 2012

Template:STRUCTURE 3i8a

Contents

Staphylococcus aureus H30N, F98Y Dihydrofolate Reductase complexed with NADPH and 2,4-diamino-5-(3-(2,5-dimethoxyphenyl)prop-1-ynyl)-6-ethylpyrimidine (UCP120B)

Template:ABSTRACT PUBMED 20026215

About this Structure

3i8a is a 1 chain structure of Dihydrofolate reductase with sequence from Staphylococcus aureus. Full crystallographic information is available from OCA.

See Also

Reference

  • Frey KM, Lombardo MN, Wright DL, Anderson AC. Towards the understanding of resistance mechanisms in clinically isolated trimethoprim-resistant, methicillin-resistant Staphylococcus aureus dihydrofolate reductase. J Struct Biol. 2010 Apr;170(1):93-7. Epub 2009 Dec 21. PMID:20026215 doi:10.1016/j.jsb.2009.12.011

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