3jwm
From Proteopedia
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{{STRUCTURE_3jwm| PDB=3jwm | SCENE= }} | {{STRUCTURE_3jwm| PDB=3jwm | SCENE= }} | ||
===Crystal structure of Bacillus anthracis dihydrofolate reductase complexed with NADPH and (S)-2,4-diamino-5-(3-methoxy-3-(3,4,5-trimethoxyphenyl)prop-1-ynyl)-6-methylpyrimidine (UCP114A)=== | ===Crystal structure of Bacillus anthracis dihydrofolate reductase complexed with NADPH and (S)-2,4-diamino-5-(3-methoxy-3-(3,4,5-trimethoxyphenyl)prop-1-ynyl)-6-methylpyrimidine (UCP114A)=== | ||
| + | {{ABSTRACT_PUBMED_020882962}} | ||
==About this Structure== | ==About this Structure== | ||
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==See Also== | ==See Also== | ||
| - | *[[Dihydrofolate reductase]] | + | *[[Dihydrofolate reductase|Dihydrofolate reductase]] |
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:020882962</ref><references group="xtra"/> | ||
[[Category: Bacillus anthracis]] | [[Category: Bacillus anthracis]] | ||
[[Category: Dihydrofolate reductase]] | [[Category: Dihydrofolate reductase]] | ||
Revision as of 08:34, 27 July 2012
Contents |
Crystal structure of Bacillus anthracis dihydrofolate reductase complexed with NADPH and (S)-2,4-diamino-5-(3-methoxy-3-(3,4,5-trimethoxyphenyl)prop-1-ynyl)-6-methylpyrimidine (UCP114A)
Template:ABSTRACT PUBMED 020882962
About this Structure
3jwm is a 2 chain structure of Dihydrofolate reductase with sequence from Bacillus anthracis. Full crystallographic information is available from OCA.
See Also
Reference
- Beierlein JM, Karri NG, Anderson AC. Targeted mutations of Bacillus anthracis dihydrofolate reductase condense complex structure-activity relationships. J Med Chem. 2010 Oct 28;53(20):7327-36. PMID:20882962 doi:10.1021/jm100727t
