3clb
From Proteopedia
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===Structure of bifunctional TcDHFR-TS in complex with TMQ=== | ===Structure of bifunctional TcDHFR-TS in complex with TMQ=== | ||
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Revision as of 10:02, 27 July 2012
Contents |
Structure of bifunctional TcDHFR-TS in complex with TMQ
Template:ABSTRACT PUBMED 18536013
About this Structure
3clb is a 4 chain structure of Dihydrofolate reductase and Thymidylate synthase with sequence from Trypanosoma cruzi. Full crystallographic information is available from OCA.
See Also
Reference
- Schormann N, Senkovich O, Walker K, Wright DL, Anderson AC, Rosowsky A, Ananthan S, Shinkre B, Velu S, Chattopadhyay D. Structure-based approach to pharmacophore identification, in silico screening, and three-dimensional quantitative structure-activity relationship studies for inhibitors of Trypanosoma cruzi dihydrofolate reductase function. Proteins. 2008 Dec;73(4):889-901. PMID:18536013 doi:10.1002/prot.22115
